Protein Alignment Hr51 and rxrgb

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_005160723.1
• Gene: rxrgb / 436617
• ZFINID: ZDB-GENE-040718-34
• Length: 465
• Species: Danio rerio
• Alignment Length: 595
• Identity: 155/595 - (26%)
• Similarity: 228/595 - (38%)
• Gaps: 187/595 - (31%)

  Fly     6 NSSETRP---SSQELHSPQRHCYTPPPAPMH--GQA----PPPTSTGVAPPTQPPPPHPAAP--- 58
            |||.::|   ||...|........|.|:||.  |.:    |.|.|......:.|....|:.|
Zfish    29 NSSPSQPPVMSSMVGHPSVISSSRPLPSPMSTLGSSMNGLPSPYSVITPSLSSPSISLPSTPSMG 93

  Fly    59 ----NVPNGRLLSWNHSAAAAAAAAAAQAAANSMNHSSAAEGSSMTRIKGQNLGLICVVCGDTSS 119
                |.|....||.|.:.........| ...|..::...:.||....        ||.:|||.||
Zfish    94 FNTLNSPQMNSLSMNGNEDIKPPPGLA-PLGNMSSYQCTSPGSLSKH--------ICAICGDRSS 149

  Fly   120 GKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQMGMNKDAVQN 184
            |||||:.:|.||.|||||::|:.|.|.|: ....|::||..||:||.||.:|||.|||.::|||.
Zfish   150 GKHYGVYSCEGCKGFFKRTIRKDLTYTCR-DIKECLIDKRQRNRCQYCRYQKCLAMGMKREAVQE 213

  Fly   185 ERQPRNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSLGSLPTGRLLH 249
            |||..     :.::..|:|......|                              .:|..::|.
Zfish   214 ERQRG-----KEKSDTEVETTSRFNE------------------------------DMPVDKILD 243

  Fly   250 HNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNVSHSTNSSSNHSIDPSSPA 314
                                     |.:...||.:.|     |..:.|:|||       ||
Zfish   244 -------------------------AELSVEPKTETY-----TESSPSNSTN-------DP---- 267

  Fly   315 PENAKEINIAGGSVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSRSDSSFIMPQFMSPNLYTH 379
                                              |||
Zfish   268 ----------------------------------VTN---------------------------- 270

  Fly   380 QHETVYETSARLLFMAVKWAKNLPSFARLSFRDQVILLEESWSELFLLNAIQWCIPLDP-----T 439
                :...:.:.||..|:|||.:|.|:.|...||||||...|:||.:.:.....|.:..     |
Zfish   271 ----ICHAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSITVKDGILLGT 331

  Fly   440 GCALFSVAEHCNNLENNANGDTCITKEELAADVRTLHEIFCKYKAVLVDPAEFACLKAIVLFRPE 504
            |..:...:.|...:.:..|              |.|.|:..|.|.:.:|..|..||:|||||.|:
Zfish   332 GLHVHRSSAHSAGVGSIFN--------------RVLTELVSKMKDMQMDKTELGCLRAIVLFNPD 382

  Fly   505 TRGLKDPAQIENLQDQAHVMLSQHTKTQFTAQIARFGRLLLMLPLLRMISSHKIESIYFQRTIGN 569
            .:||.:..::|.|:::.:..|..:||.::..|..||.:|||.||.||.|....:|.::|.:.||:
Zfish   383 AKGLSNSLEVEALREKVYASLETYTKQKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD 447

  Fly   570 TPMEKVLCDM 579
            ||::..|.:|
Zfish   448 TPIDTFLMEM 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	45/90 (50%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	59/219 (27%)
rxrgb	XP_005160723.1	Nuc_recep-AF1	27..136	CDD:463363	26/107 (24%)
		NR_DBD_RXR	139..215	CDD:143514	42/84 (50%)
		NR_LBD_RXR_like	235..443	CDD:132741	74/328 (23%)