Protein Alignment Hr51 and rxrba

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_009292297.1
• Gene: rxrba / 30530
• ZFINID: ZDB-GENE-980526-436
• Length: 480
• Species: Danio rerio
• Alignment Length: 615
• Identity: 164/615 - (26%)
• Similarity: 245/615 - (39%)
• Gaps: 195/615 - (31%)

  Fly    14 SQELHSPQRHCYTPPPAPMHGQAPPPTSTGVAPPTQPPP--------------PH---------- 54
            |::..||.....:.||:   ||..||.:...|..|..||              |.
Zfish     4 SRDSRSPDSSSVSSPPS---GQRSPPLAPSAAAMTSLPPITSAVNSPISSMGSPFSVISSSLGSP 65

  Fly    55 --PAAPNV-------PNGRLLSWNHSAAAAAAAAAAQAAANSMN---------HSSAAEGSSMTR 101
              |..|:|       |...:...|....:..:.:...|.::|.:         .||.:.|..:::
Zfish    66 CLPGTPSVGYGPISSPQMNMFPRNAEINSTVSMSGLHAVSSSDDVKPPFGLKPLSSHSPGPMVSQ 130

  Fly   102 IKGQNLGLICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQA 166
            .:      :|.:|||.|||||||:.:|.||.|||||:||:.|.|.|:.... |:|||..||:||.
Zfish   131 KR------LCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLSYTCRDNKD-CLVDKRQRNRCQY 188

  Fly   167 CRLKKCLQMGMNKDAVQNERQPRNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGS 231
            ||.:|||.|||.::.||:|||    .:::.|..|..|     |:..|.
Zfish   189 CRYQKCLAMGMKREVVQDERQ----RSVQEERQRNKE-----RDGEVE----------------- 227

  Fly   232 GLLPPPSLGSLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNV 296
                                  :||   |||               ...|.||....|||.
Zfish   228 ----------------------SSS---AAN---------------EEMPVEKILEAEMAV---- 248

  Fly   297 SHSTNSSSNHSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSR 361
                               |...|::..|.|    ..|||     ||    .|||
Zfish   249 -------------------EQKTELHADGSS----GGSSP-----ND----PVTN---------- 271

  Fly   362 SDSSFIMPQFMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSFARLSFRDQVILLEESWSELFL 426
                                  :.:.:.:.||..|:|||.:|.|:.||..||||||...|:||.:
Zfish   272 ----------------------ICQAADKQLFTLVEWAKRIPHFSELSLDDQVILLRAGWNELLI 314

  Fly   427 LNAIQWCIPLDPTGCALFSVAEHCNNLENNANGDTCITKEELA--ADV-----RTLHEIFCKYKA 484
            .:.....|.:...  .|.:...|.:....::.|...|...|.|  |:|     |.|.|:..|.:.
Zfish   315 ASFSHRSITVKDG--ILLATGLHVHRNSAHSAGVGAIFDRESAHNAEVGAIFDRVLTELVSKMRD 377

  Fly   485 VLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVMLSQHTKTQFTAQIARFGRLLLMLPL 549
            :.:|..|..||:||:||.|:.:||..|:::|.|:::.:..|..:.|.::..|..||.:|||.||.
Zfish   378 MQMDKTELGCLRAIILFNPDAKGLSSPSEVELLREKVYASLEAYCKQRYPDQQGRFAKLLLRLPA 442

  Fly   550 LRMISSHKIESIYFQRTIGNTPMEKVLCDM 579
            ||.|....:|.::|.:.||:||::..|.:|
Zfish   443 LRSIGLKCLEHLFFFKLIGDTPIDTFLMEM 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	45/90 (50%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	62/221 (28%)
rxrba	XP_009292297.1	Nuc_recep-AF1	25..127	CDD:463363	17/101 (17%)
		NR_DBD_RXR	133..208	CDD:143514	42/75 (56%)
		NR_LBD_RXR_like	235..458	CDD:132741	79/292 (27%)