Protein Alignment Hr51 and rxrbb

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_571313.1
• Gene: rxrbb / 30486
• ZFINID: ZDB-GENE-990415-242
• Length: 422
• Species: Danio rerio
• Alignment Length: 580
• Identity: 142/580 - (24%)
• Similarity: 225/580 - (38%)
• Gaps: 199/580 - (34%)

  Fly    38 PPTSTGVAPPTQP-------------PPPHPAAPNVPNGRLLSWNHSAAAAAAAAAAQAAANSMN 89
            ||:::.|:.|...             .|..|..|::..|.:.:...:::.:.:...|.::::.:.
Zfish     5 PPSTSAVSSPVSSVDSPLSAVSSSIGSPGVPGTPSIGYGPISNSQINSSMSVSRLHAVSSSDDVK 69

  Fly    90 -----HSSAAEGSSMTRIKGQNLGLICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQA 149
                 .|.:..|..:::.:      :|.:|||.|||||||:.:|.||.|||||:||:.|.|.|:
Zfish    70 PPFGLKSVSGSGPMLSQKR------MCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLSYTCR- 127

  Fly   150 GTGRCVVDKAHRNQCQACRLKKCLQMGMNKDAVQNERQPRNTATIRPETLREMEHGRALREAAVA 214
            ....|:|||..||:||.||.:|||.|||.::|||.|||
Zfish   128 DNKECLVDKRQRNRCQYCRYQKCLAMGMKREAVQEERQ--------------------------- 165

  Fly   215 VGVFGPPVLLSPPCYGSGLLPPPSLGSLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHH 279
                                                          .|....|.:...::|. ..
Zfish   166 ----------------------------------------------KNKERDGDYECSSSAN-EE 183

  Fly   280 SPKEKAYGMEMATSGNVSHSTNSSSNHSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMENDNDD 344
            .|.||....|.|    |.|.|:..|:.:..|:.|
Zfish   184 MPVEKILEAETA----VEHRTDLHSDATGSPNDP------------------------------- 213

  Fly   345 DSIDVTNDNEEPHAVSRSDSSFIMPQFMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSFARLS 409
                |||                                :.:.:.:.||..|:|||.:|.|:.:.
Zfish   214 ----VTN--------------------------------ICQAADKQLFTLVEWAKRVPHFSDVP 242

  Fly   410 FRDQVILLEESWSELF--------------LLNAIQWCIPLDPT---GCALFSVAEHCNNLENNA 457
            ..||||||...|:||.              :|.|....:|.:.|   |...|...|..::.|..|
Zfish   243 LDDQVILLRAGWNELLIAAFSHRSISVKDEILLATGLHVPKESTHNLGVEAFFDRESSHSAEVGA 307

  Fly   458 NGDTCITKEELAADVRTLHEIFCKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAH 522
            ..|            |.|.|:.||.:.:.:|..|..||:|||||.|:.:||...:::|.|:::.:
Zfish   308 LFD------------RVLTELVCKMRDMQMDKTELGCLRAIVLFNPDAKGLTSSSEVELLREKVY 360

  Fly   523 VMLSQHTKTQFTAQIARFGRLLLMLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDMYKN 582
            ..|..:.|.::..|..||.:|||.||.||.|....:|.::|.:.|||||::..|.:|.::
Zfish   361 ASLESYCKQKYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGNTPIDTFLMEMLES 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	46/90 (51%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	62/231 (27%)
rxrbb	NP_571313.1	Modulating. /evidence=ECO:0000250	1..89		11/89 (12%)
		Nuc_recep-AF1	<21..77	CDD:463363	5/55 (9%)
		NR_DBD_RXR	89..164	CDD:143514	43/75 (57%)
		Hinge. /evidence=ECO:0000250	156..178		8/94 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..182		7/94 (7%)
		NR_LBD_RXR_like	183..403	CDD:132741	75/302 (25%)