Protein Alignment Hr51 and rxrga

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_571292.3
• Gene: rxrga / 30464
• ZFINID: ZDB-GENE-980526-36
• Length: 441
• Species: Danio rerio
• Alignment Length: 565
• Identity: 149/565 - (26%)
• Similarity: 229/565 - (40%)
• Gaps: 184/565 - (32%)

  Fly    45 APPTQPPPPHPAA---PNVPNGRLLSWNHSAAAAAAAAAAQAA----------------ANSMNH 90
            :||:|||.....:   |::.||  |...:|...:::..:..|:                .||:|.
Zfish    23 SPPSQPPLSSMVSHHHPSIING--LGSPYSVITSSSLGSPSASMPTTSNMGYGALNSPQMNSLNS 85

  Fly    91 SSAAE-----------GSSMTRIKGQNLGLICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLI 144
            .|::|           ||......|.....||.:|||.|||||||:.:|.||.|||||::|:.|.
Zfish    86 VSSSEDIKPPPGLAGLGSYPCGSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLT 150

  Fly   145 YRCQAGTGRCVVDKAHRNQCQACRLKKCLQMGMNKDAVQNERQPRNTATIRPETLREMEHGRALR 209
            |.|:.... |.:||..||:||.||.:|||.|||.::|||.|||..     |..:..|::...:..
Zfish   151 YTCRDNKD-CQIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG-----RERSDNEVDSSSSFN 209

  Fly   210 EAAVAVGVFGPPVLLSPPCYGSGLLPPPSLGSLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNA 274
            |                              .:|..::|       ..:||.
Zfish   210 E------------------------------EMPVEKIL-------DAELAV------------- 224

  Fly   275 AGVHHSPKEKAYGMEMATSGNVSHSTNSSSNHSIDPSSPAPENAKEINIAGGSVSSVSSSSPTME 339
                 .||.:|| ||    .::|:|||       ||
Zfish   225 -----EPKTEAY-ME----SSMSNSTN-------DP----------------------------- 243

  Fly   340 NDNDDDSIDVTNDNEEPHAVSRSDSSFIMPQFMSPNLYTHQHETVYETSARLLFMAVKWAKNLPS 404
                     |||                                :.:.:.:.||..|:|||.:|.
Zfish   244 ---------VTN--------------------------------ICQAADKQLFTLVEWAKRIPH 267

  Fly   405 FARLSFRDQVILLEESWSELFLLNAIQWCIPLDPTGCALFSVAEHCNNLENNANGDTCITKEELA 469
            |:.|...||||||...|:||.:.:.....:.:...  .|.:...|.:....::.|...|..
Zfish   268 FSDLPLDDQVILLRAGWNELLIASFSHRSVTVKDG--ILLATGLHVHRSSAHSAGVGSIFD---- 326

  Fly   470 ADVRTLHEIFCKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVMLSQHTKTQFT 534
               |.|.|:..|.:.:.:|..|..||:|||||.|:.:||.:|:::|.|:::.:..|..:||..:.
Zfish   327 ---RVLTELVSKMREMQMDKTELGCLRAIVLFNPDAKGLSNPSEVEALREKVYASLEGYTKHNYP 388

  Fly   535 AQIARFGRLLLMLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDM 579
            .|..||.:|||.||.||.|....:|.::|.:.||:||::..|.:|
Zfish   389 DQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEM 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	46/90 (51%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	58/214 (27%)
rxrga	NP_571292.3	Modulating. /evidence=ECO:0000250	1..116		19/94 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..37		5/13 (38%)
		Nuc_recep-AF1	<40..112	CDD:463363	13/73 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..94		6/37 (16%)
		NR_DBD_RXR	115..191	CDD:143514	42/76 (55%)
		Hinge	183..206		8/27 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..210		6/26 (23%)
		NR_LBD_RXR_like	211..419	CDD:132741	76/323 (24%)