Protein Alignment Hr51 and nr2f2

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_068070812.1
• Gene: nr2f2 / 30424
• ZFINID: ZDB-GENE-990415-252
• Length: 428
• Species: Danio rerio
• Alignment Length: 564
• Identity: 173/564 - (30%)
• Similarity: 235/564 - (41%)
• Gaps: 178/564 - (31%)

  Fly    30 APMHGQAPPPTSTGVAPPTQPP-----------PPHPAAPNVPNGRLLSWNHSAAAAAAAAAAQA 83
            |..||.....|..|::.||..|           ||.|..|                      .|.
Zfish    14 AETHGTLSSQTQGGLSLPTPQPGQLGLTASQVAPPTPQTP----------------------VQG 56

  Fly    84 AANSMNHSSAAEGSSMTRI---KGQNLGLICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIY 145
            ..|:.|::.:...:..|:.   |.|...:.||||||.|||||||...|.||..||||||||.|.|
Zfish    57 PPNNNNNTQSTPTNQTTQSQSEKQQPQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY 121

  Fly   146 RCQAGTGRCVVDKAHRNQCQACRLKKCLQMGMNKDAVQNERQPRNTATIRPETLREMEHGRALRE 210
            .|:|.. .|.:|:.||||||.|||||||::||.::.                         :|..
Zfish   122 TCRANR-NCPIDQHHRNQCQYCRLKKCLKVGMRREV-------------------------SLFT 160

  Fly   211 AAVAVGVFGPPVLLSPPCYGSGLLPPPSLGSLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAA 275
            |||.                .|.:||    :.|     ||                |.|.:.|..
Zfish   161 AAVQ----------------RGRMPP----TQP-----HH----------------GQFALTNGD 184

  Fly   276 GVHHSPKEKAYGMEMATSGNVSHSTNSSSNHSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMEN 340
            .:|                  .||..|                       |.:|.:..:
Zfish   185 PLH------------------CHSYLS-----------------------GYISLLLRA------ 202

  Fly   341 DNDDDSIDVTNDNEEPHAVSRSDSSFIMPQFMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSF 405
                          ||:..||..|     |.|.|| .....|.:.|.:||:||.||:||:|:|.|
Zfish   203 --------------EPYPTSRYGS-----QCMQPN-NIMGIENICELAARMLFSAVEWARNIPFF 247

  Fly   406 ARLSFRDQVILLEESWSELFLLNAIQWCIPLDPTGCALFSVAEHCNNLENNANGDTCITKEELAA 470
            ..|...|||.||..:|||||:|||.|..:||. ....|.:...|.:.:    :.|..:.   ...
Zfish   248 PDLQITDQVALLRLTWSELFVLNAAQCSMPLH-VAPLLAAAGLHASPM----SADRVVA---FMD 304

  Fly   471 DVRTLHEIFCKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVMLSQHTKTQFTA 535
            .:|...|...|.||:.||.||::||||||||..:..||.|.|.:|:||:::...|.::.::|:..
Zfish   305 HIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPN 369

  Fly   536 QIARFGRLLLMLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDM 579
            |..|||:|||.||.||.:||..||.::|.|.:|.||:|.::.||
Zfish   370 QPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDM 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	47/90 (52%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	85/214 (40%)
nr2f2	XP_068070812.1	NR_DBD_COUP_TF	87..157	CDD:143516	45/95 (47%)
		NR_LBD_COUP-TF	191..426	CDD:132746	94/280 (34%)