Protein Alignment Hr51 and Nr2e3

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_038736.1
• Gene: Nr2e3 / 23958
• MGIID: 1346317
• Length: 395
• Species: Mus musculus
• Alignment Length: 513
• Identity: 227/513 - (44%)
• Similarity: 280/513 - (54%)
• Gaps: 121/513 - (23%)

  Fly    71 SAAAAAAAAAAQAAANSMNHSSAAEGSSMTRIKGQNLGLICVVCGDTSSGKHYGILACNGCSGFF 135
            |..||:....:.||:...:......|...|   |....|.|.||||:||||||||.|||||||||
Mouse     3 STVAASTMPVSVAASKKESPGRWGLGEDPT---GVGPSLQCRVCGDSSSGKHYGIYACNGCSGFF 64

  Fly   136 KRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQMGMNKDAVQNERQPRNTATIRPETLR 200
            ||||||:||||||.|.|.|.|||||||||||||||||||.|||:||||||||||:.|.:.   |.
Mouse    65 KRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSMAQVH---LD 126

  Fly   201 EMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSLGSLPTGRLLHHNHLTSSMQLAANHMG 265
            .||.|...|         ..||:.||...|.....|.|:.:.   |.:.| |..:|:..|
Mouse   127 AMETGSDPR---------SEPVVASPALAGPSPRGPTSVSAT---RAMGH-HFMASLITA----- 173

  Fly   266 AGSFPMFNAAGVHHSPKEKAYGMEMATSGNVSHSTNSSSNHSIDPSSPAPENAKEINIAGGSVSS 330
                             |....:|                         ||:|:|
Mouse   174 -----------------ETCAKLE-------------------------PEDAEE---------- 186

  Fly   331 VSSSSPTMENDNDDDSIDVT-NDNEEPHAVSRSDSSFIMPQFMSPNLYTHQHETVYETSARLLFM 394
                           :|||| ||.|.|.:....|.                   ::|||||||||
Mouse   187 ---------------NIDVTSNDPEFPASPCSLDG-------------------IHETSARLLFM 217

  Fly   395 AVKWAKNLPSFARLSFRDQVILLEESWSELFLLNAIQWCIPLDPTGCALFSVAEHCNNLENNANG 459
            |||||||||.|:.|.||||||||||:|:|||||.||||.:|||  .|.|.:..|        |:|
Mouse   218 AVKWAKNLPVFSNLPFRDQVILLEEAWNELFLLGAIQWSLPLD--SCPLLAPPE--------ASG 272

  Fly   460 DTCITKEELAADVRTLHEIFCKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVM 524
            .:.......:|:.|.|.|...:::|:.|||.|||||||:|||:|||||||||..:|.||||:.||
Mouse   273 SSQGRLALASAETRFLQETISRFRALAVDPTEFACLKALVLFKPETRGLKDPEHVEALQDQSQVM 337

  Fly   525 LSQHTKTQFTAQIARFGRLLLMLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDMYKN 582
            ||||:|....:|..|||:|||:||.||.:::.:||.::|::|||||||||:||||:||
Mouse   338 LSQHSKAHHPSQPVRFGKLLLLLPSLRFLTAERIELLFFRKTIGNTPMEKLLCDMFKN 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	72/90 (80%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	106/214 (50%)
Nr2e3	NP_038736.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		6/26 (23%)
		NR_DBD_PNR	32..123	CDD:143528	73/93 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..157		11/38 (29%)
		NR_LBD_Tlx_PNR_like	185..382	CDD:132748	113/250 (45%)