Protein Alignment Hr51 and unc-55

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001122482.2
• Gene: unc-55 / 192082
• WormBaseID: WBGene00006790
• Length: 370
• Species: Caenorhabditis elegans
• Alignment Length: 490
• Identity: 112/490 - (22%)
• Similarity: 180/490 - (36%)
• Gaps: 180/490 - (36%)

  Fly   111 CVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQM 175
            ||||||.|||||||..:|.||..|||||:||.|.|.|:| |..|.:|..||||||.|||.||::|
 Worm    21 CVVCGDKSSGKHYGQFSCEGCKSFFKRSIRRSLSYTCRA-TKNCAIDVQHRNQCQYCRLTKCIRM 84

  Fly   176 GMNKDAVQNERQPRNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSLG 240
            ||.|:.    |:...|.|    .:..::.||.             ||.:      ..|.||
 Worm    85 GMRKEG----RRSNETQT----AVSAVQRGRL-------------PVTM------PSLFPP---- 118

  Fly   241 SLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNVSHSTNSSSN 305
                                 |......||..:.
 Worm   119 ---------------------NMFLRSPFPFMSV------------------------------- 131

  Fly   306 HSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSRSDSSFIMPQ 370
                |.:|                                                    .:..|
 Worm   132 ----PFNP----------------------------------------------------LMTAQ 140

  Fly   371 FMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSFARLSFRDQVILLEESWSELFLLNAIQWCIP 435
            |..|::    .|:::|.:|:.:|..|.||:.  |.:.|...||:|||..||:.:|:....|....
 Worm   141 FTKPSI----KESIFEFAAQTIFATVNWART--SMSNLVKGDQLILLRHSWTPIFIFALAQSNFA 199

  Fly   436 LDPTGCALFSVAEHCNNLENNANGDTCITKEELAAD---------------------VRTLHEIF 479
            |: ....|.:|.....:.||.::.....:::|..::                     :|..|
 Worm   200 LN-LSTHLTAVTATAASTENGSSSLGSKSEDEEKSEEKPERVFDEPQFQGFQAKIDKIRDFH--- 260

  Fly   480 CKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVMLSQHTKTQFTAQIARFGRLL 544
                   :|..|.:.|:|::||..:...|::..:||.:.::....:.::.|....::  |:.::.
 Worm   261 -------LDVVESSSLRAVLLFSCDEEALEEKGKIEEIVEKLKSAVDEYCKMNKRSE--RYHQIC 316

  Fly   545 LMLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDM 579
            ..|.||:...:..|..::|.|.:|.||:|.:|.|:
 Worm   317 ECLQLLKSTRNLPISRLFFSRLLGTTPLETILSDL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	47/82 (57%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	46/235 (20%)
unc-55	NP_001122482.2	NR_DBD_COUP_TF	21..89	CDD:143516	44/68 (65%)
		NR_LBD_F2	148..325	CDD:132728	40/191 (21%)