DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr51 and nhr-74

DIOPT Version :9

Sequence 1:	NP_611032.2	Gene:	Hr51 / 36702	FlyBaseID:	FBgn0034012	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_492919.2	Gene:	nhr-74 / 191723	WormBaseID:	WBGene00003664	Length:	316	Species:	Caenorhabditis elegans

Alignment Length:	190	Identity:	50/190 - (26%)
Similarity:	76/190 - (40%)	Gaps:	47/190 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 CVVCGDTSSGK-HYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQ 174
            |.||..|...: ::||.:|..|:.||:||  ..:.|.|.|... |.:....:..|:|||.:.|::
Worm    11 CQVCQSTERTRLYFGITSCAACAAFFRRS--DGIQYMCTANNS-CTIAYDIKFFCRACRYESCVR 72

  Fly   175 MGMNKDAVQNERQPRNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSL 239
            .||.:|.|:..|..:|.|......:.|:.    ||                       |.|..||
Worm    73 AGMRRDNVRKHRTHQNQAATPGAVIPELH----LR-----------------------LTPTDSL 110

  Fly   240 GSLPTGR----------------LLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKE 283
            ||..:.|                .||.:.:|..|.::|:|.|:.:....|..||....||
Worm   111 GSSSSSRSTSPDDSEEFSDILDNTLHVSSITDLMIVSAHHEGSSTESCLNCPGVDMLDKE 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	28/83 (34%)
Hr51	NP_611032.2	NR_LBD_Tlx_PNR_like	354..569	CDD:132748
nhr-74	NP_492919.2	ZnF_C4	11..78	CDD:197701	23/69 (33%)
nhr-74	NP_492919.2	HOLI	153..301	CDD:214658	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910