DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr51 and nhr-235

DIOPT Version :9

Sequence 1:	NP_611032.2	Gene:	Hr51 / 36702	FlyBaseID:	FBgn0034012	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_496702.1	Gene:	nhr-235 / 189664	WormBaseID:	WBGene00012597	Length:	217	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	45/238 - (18%)
Similarity:	86/238 - (36%)	Gaps:	56/238 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 VSRSDSSFIMPQFMSPNLYTHQHETVYETSARLLF-------------------MAVKWAKNLPS 404
            :|.||...:  ||     |....|...|.:..:|.                   .|.::....|.
Worm     1 MSNSDEQIL--QF-----YVEHFEKALEKTQNVLLEFAESPLNHLKPTKRATDAQAFQFNSTCPG 58

  Fly   405 FARLSFRDQVILLEESWSELFLLNAIQWCIPLDPTGCALFSVAEHCNNLENNANGDTCITKEELA 469
            ...|:..::..|.::|......||....|..         |.....::.:..:.|.      :|.
Worm    59 VENLNKLEREALFQQSSFVNLWLNLAYTCSK---------SSLSFWDSRDQGSEGG------KLE 108

  Fly   470 ADVRTLHE-IFCKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVM-LSQHTKTQ 532
            ..:..||: :..::..:.:||.|||.:.||..::....|..:...:......|.:. |:.|.|.
Worm   109 VFMPRLHDSLTTEFHRIHLDPQEFATICAITTWKIHQWGTVEANTVAGQHYLAVIKELNNHHKK- 172

  Fly   533 FTAQIARFGRLL-------LMLPLLRMISSHKIESIYFQRTIG 568
             |..:..|.|.|       |::|:.||:  .:::::|  .|:|
Worm   173 -TTTMRDFERALRITEIISLLVPIGRML--QEVKTLY--ETLG 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528
Hr51	NP_611032.2	NR_LBD_Tlx_PNR_like	354..569	CDD:132748	45/238 (19%)
nhr-235	NP_496702.1	HOLI	54..195	CDD:214658	29/157 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910