DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr51 and nhr-187

DIOPT Version :9

Sequence 1:	NP_611032.2	Gene:	Hr51 / 36702	FlyBaseID:	FBgn0034012	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_504066.1	Gene:	nhr-187 / 185910	WormBaseID:	WBGene00018542	Length:	357	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	39/152 - (25%)
Similarity:	67/152 - (44%)	Gaps:	36/152 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NHSSAAEGSS----MTRIKGQNLGLICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQA 149
            ::|.|:..||    ...:.||.   .||||...::..::|:::|:.|..||:|::...:.|.|:.
Worm     4 DYSEASSSSSPEMFALNLTGQK---ACVVCKRPANCYNFGVMSCDACKMFFRRTMLLNVQYVCRR 65

  Fly   150 GTGRCVVDK---AHRNQCQACRLKKCLQMGM-------------NKDAV---------QNERQPR 189
             ..:|..|.   .....|:||||.:|:::||             ..|||         |:.|:.:
Worm    66 -KNQCFDDSFSCLKTPYCRACRLVQCVKVGMKLNLSAMLEVKNQKDDAVATLIESLLYQDARREK 129

  Fly   190 NTA---TIRPETLREMEHGRAL 208
            |..   |....||.::...|.|
Worm   130 NLMTHFTYENPTLEDIIESRQL 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	30/118 (25%)
Hr51	NP_611032.2	NR_LBD_Tlx_PNR_like	354..569	CDD:132748
nhr-187	NP_504066.1	ZnF_C4	27..98	CDD:197701	22/71 (31%)
nhr-187	NP_504066.1	HOLI	169..326	CDD:214658
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910