Protein Alignment Hr51 and nhr-14

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_741860.2
• Gene: nhr-14 / 181102
• WormBaseID: WBGene00003613
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 107/459 - (23%)
• Similarity: 168/459 - (36%)
• Gaps: 157/459 - (34%)

  Fly   111 CVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQM 175
            ||||||.:.|||||.:|||||.|||:|||.:.|.|.|:... :|.:||.|||.|:.||.:|||..
 Worm    20 CVVCGDKAIGKHYGAVACNGCKGFFRRSVWQNLQYTCRFNK-QCNIDKDHRNACRYCRFQKCLAD 83

  Fly   176 GMNKDAVQNERQPRNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSLG 240
            ||..:|:||||.                                                  .:|
 Worm    84 GMKPEAIQNERD--------------------------------------------------RIG 98

  Fly   241 SLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNVSHSTNSSSN 305
            |                                      :.:.|..|.             :|.|
 Worm    99 S--------------------------------------TKRRKRSGA-------------NSEN 112

  Fly   306 HSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSRSDSSFIMPQ 370
            :|....:|:|    :|.:.|.|||.              ..|::..|.|...|.::|.::.:..:
 Worm   113 NSDSEGTPSP----KIEVMGNSVSR--------------KLIEMLLDIEHRLASNQSMNALLRDE 159

  Fly   371 FMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSFARLSFRDQVILLEESWSELFLLNAIQWCIP 435
            ....|           :..|.:...:.|...|.....:...|:|:||::..|...||..:|..:.
 Worm   160 SEMKN-----------SRQRAVNYLIGWTNMLHPLPEVPLADKVLLLKKFSSAFTLLGTLQRSMA 213

  Fly   436 LD----PTGCALFSVAEHCNNLENNANGDTCITKEELAADVRTLHEIFCKYKAVLVDPAEFACLK 496
            |.    |....|...|.|              ..|...|..|.:.|:....:.:..|.|||:|||
 Worm   214 LPHFVLPNDQVLSISASH--------------PPELFEALTRIIDELLTPLRRLRTDHAEFSCLK 264

  Fly   497 AIVLFRPETRGLKDPAQIENLQDQAHVMLS------QHTKTQFTAQIARFGRLLLMLPLLRMISS 555
            |::|..|:..|:.:..: |.:::....:|.      .:|:....|.: |...||:::|.|..:||
 Worm   265 ALLLLNPDVVGISNNTR-ERIREARDALLKTLFAYMSNTQNSIDASL-RVSSLLMIIPSLISVSS 327

  Fly   556 HKIE 559
            ..:|
 Worm   328 SIME 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	44/82 (54%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	47/216 (22%)
nhr-14	NP_741860.2	NR_DBD_HNF4A	20..95	CDD:143518	43/75 (57%)
		HOLI	176..322	CDD:214658	38/161 (24%)