Protein Alignment Xpc and RAD34

DIOPT Version :9

• Sequence 1: NP_725451.1
• Gene: Xpc / 36697
• FlyBaseID: FBgn0004698
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_010600.1
• Gene: RAD34 / 851909
• SGDID: S000002722
• Length: 692
• Species: Saccharomyces cerevisiae
• Alignment Length: 822
• Identity: 157/822 - (19%)
• Similarity: 283/822 - (34%)
• Gaps: 277/822 - (33%)

  Fly   605 LSSKLVEKSKHQKAYTSS----KSDTSFDEKPSTSSSSKCL----KEEYSELGLSKKLLKPTLS- 660
            ::.:|:|.|::.:|...:    |.:.||.|:..|..|....    :::.|::...:..|..:|:
Yeast     1 MAKRLLESSQNDQANRKNSKIEKKEVSFYEEEETDDSFDSFYQDEEDDLSDIDWEEVSLDGSLTV 65

  Fly   661 --------SKLVLKSK---NQSSFSSN------------------KSDTSFEENPSTSSSSKSLK 696
                    .:.|.|.|   |:.:|:..                  ||...:.::   ...::.|:
Yeast    66 TFGNIRRDREKVSKYKRKHNKKAFNYQRLKYGLHLIMIPFMLFLLKSRMKWIDD---ERLNRRLR 127

  Fly   697 EETAKLSSSKLEDKKVASPA-----------------ETKTKVQSS-----------LLKRVTTQ 733
            ....||...|.:|..|..||                 .:..|:.|:           |:|....|
Yeast   128 RSVPKLIGKKFKDWDVRDPAFKMDSLRTLLLGLVLWFRSNYKMNSNGIRQNFNRLQYLIKYADNQ 192

  Fly   734 N---ISESGDSKKPKVAPVDTFSPVAGRTRRATVKPKTEEKPQVVGS-PVIPKLMLSKVKQLNAK 794
            |   ||||                        |.|...|.:.:..|: |:|
Yeast   193 NENSISES------------------------TYKKVLENQQEFYGNRPLI-------------- 219

  Fly   795 HSDTENASPANKHLQEQRNTRETRSRSKSPKVLISPSFLKKKSDGADSTSDPQKHQMAPETKARI 859
                      |..:::.|...:.:..::....|.....|:....|      |:|
Yeast   220 ----------NHGVEDIRKMAKRKMANRDILTLFFFIILENVLPG------PKK----------- 257

  Fly   860 SPNFLSEALPARQLRSRGQKASSLAIPQLDGGDDVPLPKKRPKLEKLKNSQDSDEVFEPAKPVK- 923
              .:|..|||......|..|...    |::.|           :.|:.|..||| :.:|...::
Yeast   258 --LYLCFALPLHDYDIRCNKVKW----QIEHG-----------IGKVPNRFDSD-LIQPYFWIEL 304

  Fly   924 KAPVLPKS-------VQNLRKDRRVMSTDDEGGSRLNRKTDASDMWVEVWSDVEEQWICIDL--- 978
            :.|.|...       :.:|.:...|:.|.:             |.:|..:..      .:|:
Yeast   305 EVPTLSDGELYIIDPIAHLGEREMVLKTRE-------------DQFVPTYQP------SVDMKYN 350

  Fly   979 FKGKLHCVDTIRKNATPGLAYVFAFQDDQSLKDVTARY----C-----ASWSTTVRKARVEKAWL 1034
            ...|.|.|  :|.|           ..::.|:||:.||    |     .|.|:.:.|::
Yeast   351 LNQKFHYV--VRIN-----------HAEKVLQDVSPRYVPNVCYRYFELSESSPILKSK------ 396

  Fly  1035 DETIAPYLGR------RTKRDITEDDQLRRIH-SDKPLPKSISEFKDHPLYVLERHLLKFQGLYP 1092
            ..|...||.:      :.|..:.....:::|. ::..||||::|.|....:|:...|...:.|..
Yeast   397 HYTSYQYLSKWLKVLNKKKASVHHYAIMKKIALTNFTLPKSVTEIKRTDNFVIPSLLKSNEVLKA 461

  Fly  1093 PDAPTLGFIRG----EAVYSRDCVHLLHSREIWLKSARVVKLGEQPYKVVKARPKWDRLTRTVIK 1153
            .......|.:|    |.::.|..|..|.|::.|....|.:....||.|..|..|..:|:.|.:.|
Yeast   462 CAKQAATFTKGDNSQEPIFWRRDVIQLKSKQHWAILGRSILPNAQPLKRKKYLPMRERMVRNLDK 526

  Fly  1154 DQPLEIFGYWQTQE-------YEPPTAENGIVP-----RNAYGNVELFKDCMLPKKTVHLRLPG- 1205
            ....|:|.|.||.:       |.....:..::.     :|.:||:|::.     |:|   :..|
Yeast   527 YVIKELFSYEQTMKSPKYPSTYCDHLGQEHVITDLSHYKNKFGNIEIYS-----KET---KPDGF 583

  Fly  1206 -LMRICKKLNIDC-----------------ANAVVGFDFHQGACH--PMYDGFIVCEEFREVVTA 1250
             |:.:.|:::|.|                 .:.|.||||.|...|  |..:..:|.|
Yeast   584 ELIPLSKEVDIKCLIKEYNKGKRKMQKIKYLDVVSGFDFKQKKGHAIPKIESILVKE-------- 640

  Fly  1251 AWEEDQQVQVLKEQEKYETRVYGNWKKLIKGLLIRERLKKKY 1292
              .:.:.||:||:|.|....: ..|..|::.|.:.:||..:|
Yeast   641 --TDYKAVQLLKQQTKVLLGL-SFWDILLRKLRVNDRLNAEY 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpc	NP_725451.1	rad4	345..1294	CDD:273170	157/822 (19%)
		Rad4	925..1057	CDD:281786	26/156 (17%)
		BHD_1	1062..1112	CDD:214984	13/53 (25%)
		BHD_2	1115..1170	CDD:214985	18/61 (30%)
		BHD_3	1178..1252	CDD:198100	21/99 (21%)
RAD34	NP_010600.1	RAD4	2..682	CDD:227822	157/821 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5535
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12135
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000