Protein Alignment Xpc and xpc

DIOPT Version :10

• Sequence 1: NP_725451.1
• Gene: Xpc / 36697
• FlyBaseID: FBgn0004698
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_001038675.1
• Gene: xpc / 541386
• ZFINID: ZDB-GENE-030131-8461
• Length: 879
• Species: Danio rerio
• Alignment Length: 1107
• Identity: 315/1107 - (28%)
• Similarity: 456/1107 - (41%)
• Gaps: 345/1107 - (31%)

  Fly   224 LSKRNVT-----ATPPRSQAATMDVNALLALGENQNYQSVEVEEREGNQRKKAGRGAPAAPPTLD 283
            ::||..|     ...|:..|.|...:......||    .:|.::...|. |.|.|.:......||
Zfish     1 MAKRKDTRQKSDTKKPKQIANTKSGSKTQKAKEN----GMETKKNLKNS-KVASRRSRKVKDVLD 60

  Fly   284 E-------PSRLSKTKSTRIKRHTKTRPV-------STVVANAGDT-DDSDFEEVAD-ADLSSDQ 332
            |       .|.:...:...:..|::.|.:       ..|.....|: |:.|:|||.: |......
Zfish    61 EVTSKYFQDSEVKTEEPEDLSDHSEERMIIEDTSLSKQVKEEEEDSEDEDDWEEVEEMAGPLGPV 125

  Fly   333 DDGETPNISGDLEIRVGLEGL--RPTKEQKTQHELEMALKRRLNRDIKDRQILLHKVSLMCQIAR 395
            |..|....|..:||.:....:  :..|::|.:.|.|..|:|.:||..||..:..|||.|:|.:|.
Zfish   126 DSSELALESKPVEIEIETPDMIRKRQKKEKRKAEFETYLRRMMNRFNKDLLVDTHKVHLLCLMAS 190

  Fly   396 SLKYNRLLSESDSLMQATLKLLPSRNAYPTERGTELKYLQSFVTWFKTSIKLLSPNLYSAQSPAT 460
            .|..||||.|.| |:...|.||||.....:.:.....:|:..:.||:.:. .|:|.|     |..
Zfish   191 GLFRNRLLCEPD-LLAVALSLLPSHFTTVSLKRINNGFLEGLLKWFQATF-TLNPAL-----PEE 248

  Fly   461 KEAILEALLEQVKRK---EARCKQDMIFIFIALARGMGMHCRLIVNLQPMPLRPAASDLIPIKLR 522
            ||..|..:||  ||.   .||..::|.::|:.:.|.:.:.|||:::|||:||:|..:
Zfish   249 KEVDLRTVLE--KRMGCLSARNHEEMTYLFLLVLRSLRLFCRLVLSLQPLPLKPPPA-------- 303

  Fly   523 PDDKNKSQTVESERESEDEKPKKDKKAGK--PAEKESSKSTISKEAEKKNNAKKAEAKPLSKSTT 585
                .||:|..|:..||..:.:|.....|  |..|..|.:|.:.:.::....||       |:..
Zfish   304 ----TKSKTTPSKSSSEKAQSEKSSPELKVSPGSKRPSSATAAAKEDRGGKRKK-------KTGG 357

  Fly   586 KGSETTKSGTVPKVKKELSLSSKLVEKSKHQKAYTSSKSDTSFDEKPSTSSSSKCLKEEYSELGL 650
            .|.:.......||..:..|::||:                                  .|.|:|
Zfish   358 GGDKEAAGAQKPKNSRRRSVASKV----------------------------------SYKEVG- 387

  Fly   651 SKKLLKPTLSSKLVLKSKNQSSFSSNKSDTSFEE-NPSTSSSSKSLKEETAKLSSSKLEDKKVAS 714
                                   |..:.:.|.|| .||....|               ||...|.
Zfish   388 -----------------------SEEEEEQSEEEFQPSNEDDS---------------EDSDGAV 414

  Fly   715 PAETKTKVQSSLLKRVTTQNISESGDSKKPKVAPVDTFSPVAGRTRRATVKPKTEEKPQVVGSPV 779
            ....|:||:|                                   ||:
Zfish   415 KICRKSKVKS-----------------------------------RRS----------------- 427

  Fly   780 IPKLMLSKVKQLNAKHSDTENASPANKHLQEQRNTRETRSRSKSPKVLISPSFLKKKSDGADSTS 844
                  ||||                   ||:|:..|
Zfish   428 ------SKVK-------------------QEERSEEE---------------------------- 439

  Fly   845 DPQKHQMAPETKARISPNFLSEALPARQLRSRGQKASSLAIPQLDGGDDVPLPKKRPKLEKLKNS 909
                                                                             
Zfish   440 ----------------------------------------------------------------- 439

  Fly   910 QDSDEVFEPAKPVKKAPVLPKSVQNLRKDRRVMSTDDEGGSRLNRKTDASDMWVEVWSDVEEQWI 974
            ::.:|..|..|.|||.                        .|..::...:|.|:||:.:...:|:
Zfish   440 EEEEEEEEEEKEVKKQ------------------------RRKKKQGKGADEWLEVYLESSGRWV 480

  Fly   975 CIDLFKG----KLHCVDTIRKNATPGLAYVFAFQDDQSLKDVTARYCASWSTTVRKARVEKAWLD 1035
            |:|:.:|    :| |.|    .||..:.||....|:..:||:.:||..:|.|:.|:.||:..|.:
Zfish   481 CVDVDQGVGQPQL-CSD----QATLPITYVVGLDDEGFMKDLGSRYDPTWLTSSRRRRVDSEWWE 540

  Fly  1036 ETIAPYLGRRTKRDITEDDQLRRIHSDKPLPKSISEFKDHPLYVLERHLLKFQGLYPPDAPTLGF 1100
            ||:..|....|:|...||.:::....|||||.|:||:|:||||||:|||||::.|||..|..||:
Zfish   541 ETMELYKSPDTERGQKEDQEMQAKLLDKPLPTSVSEYKNHPLYVLKRHLLKYEALYPATAAVLGY 605

  Fly  1101 IRGEAVYSRDCVHLLHSREIWLKSARVVKLGEQPYKVVKARPKWDRLTRTV-----IKDQPLEIF 1160
            .|||.||||||||.||||:.|||.||.|:|||:|||:|.......|..|.:     :||  |.:|
Zfish   606 CRGEPVYSRDCVHTLHSRDTWLKEARTVRLGEEPYKMVLGFSNRSRKARMMSEQKNVKD--LALF 668

  Fly  1161 GYWQTQEYEPPTAENGIVPRNAYGNVELFKDCMLPKKTVHLRLPGLMRICKKLNIDCANAVVGFD 1225
            |.|||:||:||.|.:|.||||.:|||.:||.||||...||:.||.|.|:.:|||||||.||.|||
Zfish   669 GTWQTEEYQPPIAVDGKVPRNEFGNVYMFKSCMLPIGCVHVHLPNLHRVARKLNIDCALAVTGFD 733

  Fly  1226 FHQGACHPMYDGFIVCEEFREVVTAAWEEDQQVQVLKEQEKYETRVYGNWKKLIKGLLIRERLKK 1290
            :|.|..|.:.||:|||||..|::.||||.:|::|..|||||.|.|...||..|:|||||:||||:
Zfish   734 YHCGFAHAVNDGYIVCEEHEEILKAAWENEQEIQQKKEQEKREKRAVTNWTLLVKGLLIKERLKR 798

  Fly  1291 KY 1292
            :|
Zfish   799 RY 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpc	NP_725451.1	rad4	345..1294	CDD:273170	285/965 (30%)
		PTZ00108	<696..924	CDD:240271	21/227 (9%)
xpc	NP_001038675.1	rad4	135..801	CDD:273170	285/968 (29%)