Protein Alignment Xpc and xpc

DIOPT Version :10

• Sequence 1: NP_725451.1
• Gene: Xpc / 36697
• FlyBaseID: FBgn0004698
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: XP_004914219.2
• Gene: xpc / 100145629
• XenbaseID: XB-GENE-991259
• Length: 1056
• Species: Xenopus tropicalis
• Alignment Length: 1314
• Identity: 359/1314 - (27%)
• Similarity: 533/1314 - (40%)
• Gaps: 410/1314 - (31%)

  Fly    58 VAGKRGSDHKAPSGIKGSSVKKRKPTGQSL----RSKLYNKYRPPPKTFPTS--PSQQKENTPRA 116
            :|.:|||:..|.:|.|    ::.:|...||    ..|.|.:.|||.|....|  .|..|:
 Frog     1 MAKRRGSEGAAVAGNK----QRNRPAIDSLHGDDEDKFYEEKRPPVKKSKDSCGDSLTKQ----- 56

  Fly   117 SGSKNAKTPNESGARNQHGPADSSSESSVEDYLVNPADLDLHSTFFAGGQKEKSPAPQFDCNAGI 181
              |..||.|..:..:            :|.....:|.:|           |.|:|..:|
 Frog    57 --SCVAKRPTVNDGK------------TVGKQTQDPPNL-----------KIKTPVKKF------ 90

  Fly   182 TNLSDSGSEDNNES--SFEDKAGNAFDFRGLLENANS------LERTRDALSKRNVTATPPRSQA 238
                 |||:|..||  .:||...|.....|..:...|      :::.|....|.|:.   .||:.
 Frog    91 -----SGSKDAEESEDEWEDVEANNQPQTGKTKRTGSENSKAGVKKERRLSVKSNIR---KRSRP 147

  Fly   239 ATMDVNALLALGENQNYQSVEVEERE----------------------GNQRKKAGRGAPAAPPT 281
            ..:|.:     ||:...:...|::|:                      |||:.:|.:.|...|
 Frog   148 GDLDAD-----GEDGFKEESSVKKRKPTVPGVKGKTKAAKPAGNASCAGNQKPRAKKSAVREP-- 205

  Fly   282 LDEPSRLSKTKSTRI----KRHTKT-RPVSTVVANAGDTDDSDFEEVADADLSSDQDDGETPN-- 339
                    ||:.|.|    ....|| |..:||      .:.|:.||..|:|  .:.:|.|..|
 Frog   206 --------KTQETEILDLLALEKKTPRKGATV------KESSESEEAEDSD--EEWEDVEELNGS 254

  Fly   340 ISGDLEIRVGLEGLRPTKEQKTQHELEMALKRRLNRDIKDRQIL-------------LHKVSLMC 391
            :..||:.....:...||:..:.:.|...|.|:||.|:.:..:..             .|||.|:|
 Frog   255 VLDDLQASTSADIPLPTQPVEIEIETAEAAKKRLRREKRKEEFAAYLRRLMKKVREDTHKVHLLC 319

  Fly   392 QIARSLKYNRLLSESDSLMQATLKLLPSR-NAYPTERGTELKYLQSFVTWFKTSIKLLSPNLYSA 455
            .:|... |.........|....|.::|.: .:.|.:| .::.||.:...||:.:..|      |.
 Frog   320 LLANGF-YRSNTCNLPDLQAVALSVVPVKFTSVPADR-VDVVYLTNLTKWFRGTFTL------SH 376

  Fly   456 QSPATKEAILEALLEQ-----VKRKEARCKQDMIFIFIALARGMGMHCRLIVNLQPMPLRPAASD 515
            :....:...:.|.||:     ..|.||    :|:.:|:.|.|.:.:..||:::|||:||:.
 Frog   377 EMSLDESESMSATLERRFGVYGVRDEA----EMVHVFLILLRALQLLSRLVLSLQPIPLKD---- 433

  Fly   516 LIPIKLRPDDKNKSQTVESERESEDEKPKKDKKAGKPAEKESSKSTISKEAEKKNNAKKAEAKPL 580
                   |..|.|             :|:|:|.    :.:.|:|...:|...|.||.|:...|
 Frog   434 -------PPAKTK-------------QPRKEKS----STRSSTKPQTAKGKSKSNNRKQVRQK-- 472

  Fly   581 SKSTTKGSETTKSGTVPKVKKELSLSSKLVEKSKHQKAYTSS---KSDTSFDEKPSTSSSSKCLK 642
                             |||:|.|||.:..|:.::....|:|   |..|:..:|...|:.    |
 Frog   473 -----------------KVKQEDSLSGESEEEEEYPVDCTTSGRGKGKTTKGKKAVKSAD----K 516

  Fly   643 EEYSELGLSKKLLKPTLSSKLVLKSKNQSSFSSNKSDTSFEENPSTSSSSKSLKEETAKLSSSKL 707
            ||.......|..|:...:||:..|.:::|  ..:.||:.|..:.|..|.....:||
 Frog   517 EEACTGARPKNQLRRKAASKVTYKEESES--CGHSSDSDFCLSASQDSDCSEWEEE--------- 570

  Fly   708 EDKKVASPAETKTKVQSSLLKRVTTQNISESGDSKKPKVAPVDTFSPVAGRTRRATVKPKTEEKP 772
                                                          |:..:.||
 Frog   571 ----------------------------------------------PLDSKRRR----------- 578

  Fly   773 QVVGSPVIPKLMLSKVKQLNAKHSDTENASPANKHLQEQRNTR---ETRSRSKSPKVLISPSFLK 834
                                       ::.|..:.::.:|||.   :.:.|:|:|
 Frog   579 ---------------------------SSGPVKEIIKMERNTNPVAKEQPRAKNP---------- 606

  Fly   835 KKSDGADSTSDPQKHQMAPETKARISPNFLSEALPARQLRSRGQKASSLAIPQLDGGDDVPLPKK 899
                 .||.|..|                                                 ||:
 Frog   607 -----TDSLSSTQ-------------------------------------------------PKR 617

  Fly   900 RPKLEKLKNSQDSDEVFEPAKPVKKAPVLPKSVQNLRKDRRVMSTDDEGGSRLNRKTDASDMWVE 964
            |.|:.....|:..||     ..::||.|:...|                          .|.|||
 Frog   618 RGKIISTDESEMDDE-----GTMEKASVVSPIV--------------------------CDQWVE 651

  Fly   965 VWSDVEEQWICIDLFKGKLHCVD-TIRK------NATPGLAYVFAFQDDQSLKDVTARYCASWST 1022
            |:.:.|.:|:|:|       ||. |:.|      .||..:.||....:...:||||.||...|.|
 Frog   652 VYLESERKWLCVD-------CVHWTVGKPQMCFNTATKPVTYVVGIDNAGCVKDVTRRYDVDWMT 709

  Fly  1023 TVRKARVEKAWLDETIAPYLGRRTKRDITEDDQLRRIHSDKPLPKSISEFKDHPLYVLERHLLKF 1087
            :.||.|||..|.:||:.||......|:..|:.:|.....|:|||.||:.:||||||||:|||||:
 Frog   710 STRKRRVEPDWWEETLMPYKNPDADREDREEVELEFKLLDQPLPTSITGYKDHPLYVLKRHLLKY 774

  Fly  1088 QGLYPPDAPTLGFIRGEAVYSRDCVHLLHSREIWLKSARVVKLGEQPYKVVKA---RPKWDRLTR 1149
            :.:||..|..||:.||||||||.|||.|||.:.|||.||||:|.|.|||:||.   |.:..|.:.
 Frog   775 EAIYPETAAILGYCRGEAVYSRSCVHTLHSSDTWLKEARVVRLAEVPYKMVKGYSNRARKARSSD 839

  Fly  1150 TVIKD-QPLEIFGYWQTQEYEPPTAENGIVPRNAYGNVELFKDCMLPKKTVHLRLPGLMRICKKL 1213
            ...|| ..|.::|.|||:||:||.|.:|.||||.||||.||:.||||....|||:|.|.|:.:||
 Frog   840 PQKKDHNDLGLYGLWQTEEYQPPLAVDGKVPRNEYGNVYLFQPCMLPIGCAHLRVPNLHRVARKL 904

  Fly  1214 NIDCANAVVGFDFHQGACHPMYDGFIVCEEFREVVTAAWEEDQQVQVLKEQEKYETRVYGNWKKL 1278
            :|||..|:.|||||.|..||:.||::||||.::::.||||.:|.....|::||.|.|..||||.|
 Frog   905 DIDCVKAITGFDFHGGYSHPVNDGYVVCEEHKDILLAAWENEQADIEQKQKEKREKRALGNWKLL 969

  Fly  1279 IKGLLIRERLKKKY 1292
            :||||||||||.:|
 Frog   970 VKGLLIRERLKARY 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpc	NP_725451.1	rad4	345..1294	CDD:273170	283/984 (29%)
		PTZ00108	<696..924	CDD:240271	23/230 (10%)
xpc	XP_004914219.2	rad4	272..984	CDD:273170	281/972 (29%)