DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ND-51L2 and ndufv1

DIOPT Version :9

Sequence 1:	NP_725449.1	Gene:	ND-51L2 / 36695	FlyBaseID:	FBgn0034007	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001003747.1	Gene:	ndufv1 / 445291	ZFINID:	ZDB-GENE-040808-73	Length:	492	Species:	Danio rerio

Alignment Length:	439	Identity:	231/439 - (52%)
Similarity:	295/439 - (67%)	Gaps:	13/439 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DPPKGYEPNCKTKFGPLDDCDRVFQNLYGRHDWRLHGACQRGDWHRTAELLEQGPEWIMKQVSKS 106
            :.||      |||||||.|.||:|.||||||||||.||.:||||::|.|:|::|.:||:.::..|
Zfish    56 ETPK------KTKFGPLADQDRIFTNLYGRHDWRLKGALRRGDWYKTKEILDKGVDWILNEIKTS 114

  Fly   107 GLRGRGGAGFYAGLKWEFLRQTKSEKVPKMVIVNCAEGEPGTCKDRDILRHEPHKLIEGILLVGV 171
            ||||||||||..|:||.|:.: .|:..||.::||..||||||||||:|:|::|||||||.|:.|.
Zfish   115 GLRGRGGAGFPTGMKWSFMNK-PSDGRPKYLVVNADEGEPGTCKDREIMRNDPHKLIEGCLVAGR 178

  Fly   172 AMGCGRAIVYIRNRFYNEACNLHFALAEAYHHGLLGNSVCGTGIKFDVMVQRG-DRYLCGEETAM 235
            |||...|.:|||..||||:.||..|:.|||..||:|.:.||:|..|||.|.|| ..|:||||||:
Zfish   179 AMGARAAYIYIRGEFYNESSNLQVAINEAYAAGLIGKNACGSGYDFDVFVMRGAGAYICGEETAL 243

  Fly   236 INCLMGKLGRPRRRPPFLTEKGYFEHPCLVINAESIAVVPTILRRGSQWWAGLGRSYNTGTKLYC 300
            |..:.||.|:||.:|||..:.|.|..|..|.|.|::||.|||.|||..|:||.||..|:||||:.
Zfish   244 IESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVAPTICRRGGTWFAGFGRERNSGTKLFN 308

  Fly   301 LSGQVNNPCTVEEEMSIPLKDLIERHAGGVKGGWDNLAAVFPGGLSTPLLDPSTAGKVLMDFDSL 365
            :||.||||||||||||||||:|||||||||:||||||..|.|||.||||:.......||||||:|
Zfish   309 ISGHVNNPCTVEEEMSIPLKELIERHAGGVRGGWDNLLCVIPGGSSTPLIPQHVCDTVLMDFDAL 373

  Fly   366 TDAGSGFGCGAVIVMTKDCDPLAIMLRSIQFFEKHTCKQCSYCRDGAIWLPEIFARFVKGQTHPH 430
            ..|.:|.|..|:|||.|..|.:..:.|.|:|::..:|.||:.||:|..|:.::..|||||.....
Zfish   374 IQAQTGLGTAALIVMDKSTDVIRAIARLIEFYKHESCGQCTPCREGVDWMNKMMWRFVKGDARSA 438

  Fly   431 EID--WTLVIADKMRNSKPICALAYSQVSVAESLVRMFSRKIEERLLKY 477
            |||  |.:   .|......||||........:.|:|.|...:|.|:..:
Zfish   439 EIDMIWEI---SKQIEGHTICALGDGAAWPVQGLIRHFRPLMESRIADF 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-51L2	NP_725449.1	PTZ00304	55..477	CDD:185547	226/424 (53%)
		Complex1_51K	103..275	CDD:279808	94/172 (55%)
		SLBB	298..>335	CDD:287499	30/36 (83%)
		NADH_4Fe-4S	389..466	CDD:287548	26/78 (33%)
ndufv1	NP_001003747.1	PRK13596	66..487	CDD:237441	223/423 (53%)
		Complex1_51K	111..280	CDD:279808	92/169 (54%)
		SLBB	306..358	CDD:287499	41/51 (80%)
		NADH_4Fe-4S	397..478	CDD:287548	27/83 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1894
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D272111at33208
OrthoFinder	1	1.000	-	-		FOG0003103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11780
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810