Protein Alignment Trpm and trpm5

DIOPT Version :9

• Sequence 1: NP_001097320.1
• Gene: Trpm / 36694
• FlyBaseID: FBgn0265194
• Length: 2023
• Species: Drosophila melanogaster
• Sequence 2: XP_017212363.1
• Gene: trpm5 / 557722
• ZFINID: ZDB-GENE-060503-736
• Length: 1165
• Species: Danio rerio
• Alignment Length: 1190
• Identity: 345/1190 - (28%)
• Similarity: 575/1190 - (48%)
• Gaps: 189/1190 - (15%)

  Fly   179 GTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIR 243
            |.|:|.|.:. |:.::||::..|.|..:.|:.||:|.|..|.|::.:.||.....|:..|:..:|
Zfish    18 GDIDFTGVSR-TRGKFVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLR 81

  Fly   244 KGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTG---RVVSIGIAPWGIVERNHELLGH 305
            |||:|||::|||||.|.|...|:||.:|.|:.......|.   |||:||||||.:::....||..
Zfish    82 KGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLLLSA 146

  Fly   306 NREVPCHSISSPRSKL---AV--LNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFT 365
            .   |.|..:.|...|   ||  |:..|::|:|||...: :.||...:|.|:.|.||   |....
Zfish   147 K---PDHPATYPTEDLPYGAVYSLDCNHSHFILVDEDPK-RPGATGEMRVKMLKHIS---LQRTG 204

  Fly   366 HSST-----PVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL-AFVHKYASDGEEQ 424
            :..|     ||:||::.|....::.:.:.:.:|  :|.::..|||..||:| ..:.:...|.
Zfish   205 YGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNS--IPWLILAGSGGVADILVTLMDRGCWDA--- 264

  Fly   425 PVLESMRDYLIGTIQKTFEVGLDQSE-----KLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQ 484
               :.:::.||    .||..||..:|     ||.|.:|.   :.:|:||    ..||.:: |||.
Zfish   265 ---DIVQELLI----NTFPDGLHSTEITSWTKLIQRILD---HGHLLTV----HDPEQDS-ELDT 314

  Fly   485 TILTALFKSQHLSPPE------QLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRI 543
            .||.||.|:......|      :|.||:.|||||||:||||....:|....|:|.||:||.:|:.
Zfish   315 VILKALVKACKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKP 379

  Fly   544 DFVKLLLENGVSMKKFLTIPRLEELY------NTKH---------------------GPANTLGY 581
            |||:|.::|||::|:|||..||:|||      |..|                     .|.|.||
Zfish   380 DFVRLFVDNGVNIKQFLTYGRLQELYCSVSEKNLLHTLLLKKNQERQAQLARKRMSGNPNNELG- 443

  Fly   582 ILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQ 646
                     .:.:.:|.|::..|:...:....:.:|.:..            |....|...:..|
Zfish   444 ---------DRKFRFTFHEVSKVLKDFLDDTCKGFYQKLP------------AERMGKGRLFHSQ 487

  Fly   647 RYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLY 711
            :.            ||......  |.|:.:|.:||:|..||:||...|..|.||:|.:||.||:.
Zfish   488 KN------------LPDMDRRC--EHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIM 538

  Fly   712 KAMAHEAAEDDLDTEIYEELRSYAK-EFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLS 775
            |.|||.|.|       .|..||... ::|.....|....|....::|..||..:...||..:.|:
Zfish   539 KEMAHLATE-------AESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLN 596

  Fly   776 LAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQT 840
            :|..|..:...||...|.:|..:|.|.:||..:     |..|.:.|:|..|.:.|..:.....|.
Zfish   597 IATLAEAKCFFAHDGVQALLTKVWWGAMRTDTS-----ISRLVLTFFIPPLVWTSLIKFNPEEQV 656

  Fly   841 EEEHLEN-QNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNE 904
            .::..|. ..||:.:::::     .||.|    .|....|....:...|.:|.|
Zfish   657 SKDEGEPFAELDSLETEQA-----LLLTD----GDPVAGEGSAETAARSCSATF----------- 701

  Fly   905 VKQHQPLR-LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRW----QEWYSIAY 964
                  :| :.:::..|::||:|.|..:.|.|..|||:||:.:|:.....|.:    .|.....:
Zfish   702 ------IRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSAAEIILYFW 760

  Fly   965 ITTLGFEKVRE-IISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIGRVIYC 1028
            :.||..|::|: ..:.|.::|..|..::..:.||.||..||.|||:||:.|...:|.:.||.:..
Zfish   761 VFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAMSTYEAGRTVLA 825

  Fly  1029 VDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWS 1093
            :|.:.:.||:::|..::|.|||.:.::.:|:|::.:|:..|:|.|:::||:.||:|:||......
Zfish   826 LDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDW 890

  Fly  1094 LIKEVTFQPYFMLYGEVFAGDIDPP------CGEDPSQ------PGC--VTGHWVTPITMSMYLL 1144
            :.:...::||..::|::...:||..      |..|..:      |.|  :..:|:..:.:.:|||
Zfish   891 VFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLL 955

  Fly  1145 IANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVR 1209
            :.|:||:|||||:|:..|..|...:...|.|||:.:::||..:|.|.||||.:.|....|...::
Zfish   956 VTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQALLSFIK 1020

  Fly  1210 KAKG----LEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVET 1270
            |.:.    ||.:..:||.        ::|..:|....|.:..:.|....:|:.||::.|:.:|:|
Zfish  1021 KTENTQDLLERELPSGLD--------QKLMTWETVQKENYLAKLEHEHRESSGERLRYTSSKVQT 1077

  Fly  1271 MSQKIEDINQKENIQTATVQ 1290
            :.:.:.....:|. :.|||:
Zfish  1078 LLRMVGGFKDQEK-RMATVE 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trpm	NP_001097320.1	Ion_trans	951..1167	CDD:278921	69/234 (29%)
		TRPM_tetra	1262..1313	CDD:293127	7/29 (24%)
trpm5	XP_017212363.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323456at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850