Protein Alignment Trpm and F13B12.3

DIOPT Version :9

• Sequence 1: NP_001097320.1
• Gene: Trpm / 36694
• FlyBaseID: FBgn0265194
• Length: 2023
• Species: Drosophila melanogaster
• Sequence 2: NP_501927.2
• Gene: F13B12.3 / 184410
• WormBaseID: WBGene00008731
• Length: 717
• Species: Caenorhabditis elegans
• Alignment Length: 749
• Identity: 139/749 - (18%)
• Similarity: 278/749 - (37%)
• Gaps: 216/749 - (28%)

  Fly   668 ALFEFPFNEL------------------LIWAVLTKRQQMALLMWTHGEEALAKSL----VSCKL 710
            ::|||..|.:                  ||.:...||..:..: |...|..:...|    ||.|:
 Worm    76 SIFEFINNTMQPILKCHLSQVKDTNMLHLIASSFFKRSDLHEI-WAKCEYPIFAGLLVVYVSEKM 139

  Fly   711 YKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSW------- 768
            .|..:.:  .:.:..|.:|::::   .|:.:...|||..:.......:.:|....|.:
 Worm   140 RKLFSGQ--HEPVIAEAFEKIQN---SFDDECTALLDQCFHTSERDTRAVLDTNYHLFIHTDGCP 199

  Fly   769 ---SNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMP--FYIRQLDF 828
               .:...::||.||..:..|:||..|..:...|..|.:..:...|   |....|  |::|....
 Worm   200 SVEEDMEVMALASAAKAKNFLSHPACQREIDFRWQPGFKLGQMAFF---LFFFFPPLFFLRGKQR 261

  Fly   829 KSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQF 893
            ..|.|::.|                          .|..|         |.....|:|.|:
 Worm   262 IKKREIKTM--------------------------MLKMD---------HSGNMTSITYSN---- 287

  Fly   894 REFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVL------VKMEQ 952
               |.:..||                |||:|..|:...::..:.::|.:::.::      :.|.:
 Worm   288 ---FLIRVYN----------------FYTSPNAKYVIHTLFRLIYVIFYAYVLMTMTRKTMVMNE 333

  Fly   953 MPRWQEWYSI-----AYITTL-------GF-----EKVREIISSEPVAITHKFSVWAWNM----- 995
            :..:.:..:|     ||:|.:       ||     ....::..:..||:|    :.||::
 Worm   334 LDEFLDEMAIIVWQCAYLTEMAVLVYQRGFYNWAERNTADLYRNYLVAMT----MIAWSVAVIAP 394

  Fly   996 --WNPCDGAAIILFVIGLAFRFRENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKM 1058
              | |....|||...:...|.|                ::..||::.|..|:.:.|.:|.|:.||
 Worm   395 PTW-PIRAFAIISADLFFYFSF----------------VFATLRLMKIANVDAFFGSIVLMIKKM 442

  Fly  1059 VKNMIYFVVLLAVVLMSFGVSRQA-------------ILYPNKQPTWSLIKEVTFQPYFMLYGEV 1110
            :..|:.|:.:..|...::.|...:             :::|     |.:.....|:    ::||
 Worm   443 IPIMVKFMFVFMVFWFTYAVCHISLAGHLKSTPNITDVVWP-----WLIFSSGAFE----IFGE- 497

  Fly  1111 FAGDID-----PPCGEDPSQPGCVTGH----W----VTPITMSMYLLIANILLINLLIAVFNNIF 1162
             |.:.|     ..|...|.....:|..    |    :.|:.:..|:|::::||:||:.|:.:..:
 Worm   498 -ADEEDKLGTVSKCSSAPLNWDVITDSSVQCWFKTSMIPVFLFCYMLVSSVLLVNLVTALLSKKY 561

  Fly  1163 NEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRKAK----------GLEVQ 1217
            .:::.|||..|.::.::.::||::|..:|.|...|  ||.|..:|...:|          .:::.
 Worm   562 EDIDKVSHIYWKYKLYSRLIEYEEKLWIPAPLSLL--FYILKTFCFFLSKIPIIGVIPNYFMKIL 624

  Fly  1218 RDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKE 1282
            .....|::.::....|.|   |..:.|...........:.||  |.:.|.|......:|...:::
 Worm   625 HIFEGKVYAKERRKNRKY---EAVMNGLISNPNRWDGPTEDE--KKSVELVREQMSILEADRKRK 684

  Fly  1283 NIQTATVQNIEFRLRKMEESSEQILSHLAVIHRF 1316
            .::|..::.          ..|:|:|.:...:||
 Worm   685 RLETDLIRT----------RFEEIMSEIENTNRF 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trpm	NP_001097320.1	Ion_trans	951..1167	CDD:278921	50/265 (19%)
		TRPM_tetra	1262..1313	CDD:293127	8/50 (16%)
F13B12.3	NP_501927.2	Ribosomal_L29_HIP	673..>712	CDD:299132	7/46 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13800
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100