Protein Alignment ItgaPS4 and Itga9

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_038938627.1
• Gene: Itga9 / 685004
• RGDID: 1311191
• Length: 1036
• Species: Rattus norvegicus
• Alignment Length: 1161
• Identity: 274/1161 - (23%)
• Similarity: 485/1161 - (41%)
• Gaps: 264/1161 - (22%)

  Fly     5 LVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLV----IREKSIMVAAPRANSSL 65
            |::.|:|......||||.  ....:.|....|    |:||::::    ...:.::|.||:|:|..
  Rat    17 LLLALVAAGVPAGAYNID--AQRPVRFQGPPG----SFFGYAVLEHFHDNTRWVLVGAPKADSKY 75

  Fly    66 EAQRNISEPGVIFRC--YFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGGTRD 128
            ..  ::..||.:|:|  :......|:..::..:.| :| .:.|.....::|..|:|.::....:.
  Rat    76 ST--SVKSPGAVFKCRVHTNPDRRCTELDMARERN-RG-ESCGKTCRGDRDDEWMGVSLARQPKA 136

  Fly   129 SDKFLVCAPRFYSINNENDY--NNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIP 191
            ..:.|.||.|:.:|..|.|:  .:|.||.:   |.|:.:...|                   |||
  Rat   137 DGRVLACAHRWKNIYYETDHILPHGFCYLI---PSNLQAKGRM-------------------LIP 179

  Fly   192 YY-----SMGE------LGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRGM 245
            .|     ..||      .|::...:::  .::|||||...|.|::.:.....
  Rat   180 CYEEYKKKYGEEHGSCQAGIAGFFTEE--LVIMGAPGSFYWAGTLKVLNLTD------------- 229

  Fly   246 NTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIF--DIY 308
            ||..|.|:     .......::|.||||::|:|...:::.|  |..||: :...|:.|||  |..
  Rat   230 NTYFKLND-----DAIMNRRYTYLGYAVTAGHFSHPSVTDV--VGGAPQ-DEGIGKVYIFRADRR 286

  Fly   309 EDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYA-LRNSYDDGAIYVFINKGSFT 372
            ..::.|..:..|...|.|||.|:.|.|||.||.:|:::.||::: :|   |:|.:.|::|:|...
  Rat   287 SGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVGAPMFSEIR---DEGQVTVYLNQGHGV 348

  Fly   373 FEERI-IRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAGN--GSVFIYLGSENGLRDPPSQ 434
            .||:: :...|.....||.:::.:||::.||:.|||||||...:  |:|:||.|...|:....|.
  Rat   349 LEEQLTLTGDAAYNAHFGESIASLGDLDDDGFPDVAVGAPMEDDFAGTVYIYHGDAQGIVPQYSM 413

  Fly   435 CLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKIHA------- 492
            .|......|.   ..|||..:|.|.|:||||:.|..:||..:::|.|.||.||:.:..
  Rat   414 KLSGRKINPI---LQMFGQSISGGIDMDGNGYPDVTVGAFLSDSVVLLRARPVITVDVSIFLPGS 475

  Fly   493 --IIKPKLQNVNPEEERVNITVCYRLSSKSDSKAKALMEQELVIRIDIDTKSKIKLA----VFDE 551
              |..|:..:.......:|:|||:|...|:......|   ...:..|:..|.|.:|.    |...
  Rat   476 INITAPQCHDGQQPVNCLNVTVCFRFHGKNVPGEIGL---NYNLTADVAQKEKGQLPRVYFVLLG 537

  Fly   552 EHGSQMSFKAKAFH-EEICSEFQIEMDKRAK--FTPIALEMQYELSKKIPNSGDFCEDCAVVDPA 613
            |...|:|.:.:..| :|:|..:...:.:|.:  .:||..|..|.|.:.:...    ||..:.|
  Rat   538 ETAGQVSERLQLTHMDEVCHHYVAHVKRRVQDVISPIVFEAAYSLGEHVIGE----EDRELPD-- 596

  Fly   614 EPKFVTEYI--------------TFNTGCATDVCVADLK------ISCINASST-LVLGTTAVLR 657
                :|..:              .|...|.::.|.|||:      :|.::..:| |.||....:.
  Rat   597 ----LTPVLRWKKGQRIAQKNQTVFERNCRSEDCAADLQLRGKLLLSSVDEKTTHLALGAVKNIS 657

  Fly   658 LTYNITNNGEFAYHPKFSVTNSAGL------SLAQVPGNCKVNEA-VMVCDLNHGQRMAKGDTDS 715
            |..:|:|.|:.||....|...|..|      ...::..:|::.|: .:.|.:......:|...:
  Rat   658 LNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYE- 721

  Fly   716 LTISFDVRQLRGRSLEIQAEVLSARDESNPE------NNKLTNVLSLREKADIYVSGVQTNDHVV 774
            .::.||...|.|.. ||.:.:::|: ..|.|      :|.||..:.|..:.|..::|:.:....|
  Rat   722 FSVIFDTSHLSGEE-EILSFIVTAQ-SGNMERSEALHDNTLTLTIPLVHEVDTSITGIVSPTSFV 784

  Fly   775 LKESPYTAEVVNYYEIKSH-------------GPSTLENLTVSLYIPVAYKTP---DSTNVKHIV 823
            ..||...:..:...:.:.|             |||||...:||:..| :..:|   :...|:.:|
  Rat   785 YGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFP-SRLSPGGAEMFQVQDMV 848

  Fly   824 TSSPKIQSKYAHKIMPINFIDQNNALANNFAIDHDQSTLLFSATPQHENVGNLSGIVEQNPSISL 888
            .|..|                                             ||.|  :::||:..:
  Rat   849 VSQEK---------------------------------------------GNCS--LQRNPTPCI 866

  Fly   889 L-NEDLPVNNTL----------VLNCQDTNVTLCVPVEIRLENGLQLKPEEL----MNMTVSFTV 938
            : .|...:.:|:          ||:|:.|. :.|:.:...|.   .|..||.    :.|.::..:
  Rat   867 IPQEQENIFHTIFAFFSKSGRKVLDCEKTG-SFCLTLHCNLS---ALPKEESRAIDLYMLLNTEI 927

  Fly   939 NLKDADDIWEYFV-----IQTDLKVHKI--GDP--TLSSFTIEKKIESNVICKHAEIAIWKIIVS 994
            ..||:..:.::..     ::..|:|.:|  |:|  ||..|.....:|     ....:..|.|.:|
  Rat   928 LKKDSSSVIQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLE-----PRGYVVGWIIAIS 987

  Fly   995 VIVGILVFSAATYALYKRGFFKRAIKDDLKQLIRDSFEDGIIRTEMEENAQSQGDA 1050
            ::||||:|......|:|.|||:|..|:.:               |.|:|.:...:|
  Rat   988 LLVGILIFLLLAVLLWKMGFFRRRYKEII---------------EAEKNRKENEEA 1028

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	25/74 (34%)
		Int_alpha	384..434	CDD:214549	19/51 (37%)
		Int_alpha	447..>492	CDD:214549	19/44 (43%)
		Integrin_alpha2	484..808	CDD:285619	83/386 (22%)
Itga9	XP_038938627.1	Int_alpha	45..102	CDD:214549	14/62 (23%)
		Int_alpha	245..295	CDD:214549	17/52 (33%)
		Int_alpha	301..347	CDD:214549	20/48 (42%)
		Int_alpha	362..415	CDD:214549	20/52 (38%)
		Int_alpha	425..>467	CDD:214549	19/41 (46%)
		Integrin_alpha2	460..904	CDD:400650	101/508 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335745
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23220
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950