Protein Alignment ItgaPS4 and itga11b

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_695559.7
• Gene: itga11b / 567175
• ZFINID: ZDB-GENE-071009-4
• Length: 1219
• Species: Danio rerio
• Alignment Length: 1113
• Identity: 238/1113 - (21%)
• Similarity: 413/1113 - (37%)
• Gaps: 316/1113 - (28%)

  Fly    92 NIDTKGNYKGMPNDGLLTAKNKDFRWLGG----------AMDGGTRDSD---------------- 130
            |||.:|..:.....|:..|:.:.|:. ||          ..||.:.||.
Zfish   267 NIDQRGGEETRTALGINVARTQAFKH-GGRPDAKKVMIVITDGESHDSPDLKAAVEESEKDNITL 330

  Fly   131 -----------------------KFLVCAP--RFYSINNENDYNNGMCYWLSDTPKNIDSTEVME 170
                                   ||:...|  .|:|:.:|:.        |.|.   :|:.
Zfish   331 YGIAVLGYYNRRGINPEAFLREIKFIATDPDEHFFSVTDESA--------LKDI---VDAL---- 380

  Fly   171 KWPLRIEKKQVLKLADTN-------LIPYYSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLK 228
                   .:::..|..||       |    .|.:.|.|:|:.:|.  :|:||.|...|.|:| ||
Zfish   381 -------GEKIFSLEGTNQNGTAFGL----QMSQAGFSSHIVEDG--ILVGAVGAYDWNGAV-LK 431

  Fly   229 QEVPSIKTSSGRQRRGMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAP 293
            :      |..|:.....::..|  |...|.||.|    :|.||.|||..   |.....||||.||
Zfish   432 E------TRHGKVIPPKSSYMK--EFPEELKNHG----AYLGYMVSSVV---SAHHGQLYVAGAP 481

  Fly   294 RGNNQFGEAYIFDIYEDS----IYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTD-VIISAPLYAL 353
            |.|:. |:..||.:....    :|..:   |...|.|:|..:...|::.||.|| :::.||:|..
Zfish   482 RFNHT-GKVVIFTLTNSGNLTILYSLY---GKQIGSYYGSELAPIDVDDDGLTDLLLVGAPMYFY 542

  Fly   354 RNSYDDGAIYVFI--NKGSFTFEERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAGN- 415
            | .::.|.:|::.  .:|||..:..:..|......|||..:|.:.|:|.||::::.||||...|
Zfish   543 R-GWEKGKVYIYTVGLQGSFIPDGTLGPSEHSHDSRFGAAMSALPDLNGDGFSELVVGAPLEDNH 606

  Fly   416 -GSVFIYLGSENGLRDPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAV 479
             |:::::.|.:|.::....|.:......|   |...||..:....|::|:|..|.::|:..|..:
Zfish   607 RGAIYLFYGLKNSIQTKYKQRISGIELAP---GLRYFGRSVHGMMDLNGDGLVDLSVGSFGAAVL 668

  Fly   480 YLYRAYPVVKIHAIIKPKLQNV--------NPEEERVNITVCYRLSSK---SDSKAKALMEQELV 533
            ...|:...|.|....:|...||        ..|...:..|||..::::   :|.|..||.
Zfish   669 LWSRSVVRVGIGVHFEPSKINVFNKDCIRGGREVSCMLATVCLNVTARTPMTDPKRVALR----- 728

  Fly   534 IRIDIDTKSKIKLAVFDE-EHGSQMSFKAKAFHEEICSEFQIEMDKRAKFT-PIALEMQYELSKK 596
            .....:.......||.|. |....::.:..|.|   |.:....:.:...:| |:...:...|.:
Zfish   729 YSFGFEETGYFPRAVLDSTEESRDVTLRPAAQH---CQQLHFHVHEVTDYTRPLTFTVNVGLQR- 789

  Fly   597 IPNSGDFCEDCAVVDPAEPKFVTEYITFNTGCAT-DVCVADLKIS-------------------- 640
                   .::..|:|...|..:...:.|..||.. |.||.:|.:.
Zfish   790 -------ADEGPVLDDGWPTSLRSELPFWNGCDNDDQCVPNLILQSSSDLLDLREFCSRDERSSW 847

  Fly   641 --CINASS-----TLVLGTTAVLRLTYNITNNGEFAYHPKFSVTNSAGLSLA------------Q 686
              |::.||     .||..:...:.:..::.|.||.||:....:|:|..|..:            :
Zfish   848 PPCVDQSSIKTPERLVESSRRKVVVETHLENRGENAYNSILHITHSPNLHFSSLVVKAPSDIAIE 912

  Fly   687 VPGN--------CKVNEAVMVCDLNHGQRMAKGDTDSLTISFDVRQLRGRSLEIQAEVLSARDES 743
            .|.:        |.|:...|........|:....:.|:.:::         :.|...|.|..:|.
Zfish   913 CPNSDDTSLYRTCNVSAPFMRASAQVYFRLEFEFSRSVFLNY---------VNISLRVSSEGEEM 968

  Fly   744 NPENNKLTNV-LSLREKADIYVSGVQTNDHVVLKESPYTAEVVNYYEIKSHGPSTLENLTVSLYI 807
            .||:| :.|: .:||.:||:    :.|.|     .||      :.:|||   |...::::|.
Zfish   969 FPEDN-VNNIHHNLRYEADL----LFTRD-----SSP------SRFEIK---PEQAQSVSVG--- 1011

  Fly   808 PVAYKTPDSTNVKHIVTSSPKIQSKYAHKIMPINFIDQNNALANNFAIDHDQSTLLFSATPQHEN 872
                             |.|.....|..:.:.:..:.:.....|.||:....:|||
Zfish  1012 -----------------SGPPFNLSYQIQNLGLFPVSELLFTLNVFAVTRKANTLL--------- 1050

  Fly   873 VGNLSGI-VEQNP------------SISLLNEDLPVNNTLVLNCQDTNVTLCVPVEIRLENGLQL 924
              :||.: ::|.|            ..|...|||.:|..:..:..|..:..|         ...|
Zfish  1051 --HLSDLYIQQMPGSLCSFPRVITAGSSSQEEDLSLNAHMNASTSDALLAQC---------RFNL 1104

  Fly   925 KPEELMNMTVSFTVNL--------KDADDIWEYFVIQTDLKVHKIGDPTLSSFTIEKKIESNVIC 981
            .|:..:::||:..:||        |..|     .|:...:::    .|:...|..|::...::|.
Zfish  1105 SPQADVSITVTGWLNLHTLLAVKFKRLD-----LVMTATVEL----SPSNPMFLHEERPMRHIIL 1160

  Fly   982 -----KHAEIAIWKIIVSVIVGILVFSAATYALYKRGFFKRAIKDDLKQLIRDSFEDGIIRTEME 1041
                 :...|.:|.||.|.:.|:.:.:....||:|.|||.|..:.               |.|.|
Zfish  1161 EIRKEEDYRIPVWVIIGSTLGGLQLLALLVLALWKLGFFHRQKRK---------------RDEQE 1210

  Fly  1042 ENAQSQGD 1049
            .|.::..|
Zfish  1211 ANEKTAED 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	23/75 (31%)
		Int_alpha	384..434	CDD:214549	16/51 (31%)
		Int_alpha	447..>492	CDD:214549	12/44 (27%)
		Integrin_alpha2	484..808	CDD:285619	73/385 (19%)
itga11b	XP_695559.7	Int_alpha	73..123	CDD:214549
		vWA_integrins_alpha_subunit	199..376	CDD:238746	20/117 (17%)
		Int_alpha	574..628	CDD:214549	17/53 (32%)
		Int_alpha	639..>665	CDD:214549	7/25 (28%)
		Integrin_alpha2	671..1071	CDD:312071	87/474 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574928
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840