Protein Alignment ItgaPS4 and itga11a

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001166098.2
• Gene: itga11a / 541475
• ZFINID: ZDB-GENE-050324-1
• Length: 1190
• Species: Danio rerio
• Alignment Length: 1129
• Identity: 251/1129 - (22%)
• Similarity: 427/1129 - (37%)
• Gaps: 320/1129 - (28%)

  Fly    35 EGNRRSSYFGFSLVIREKSIMVAAPRANSSLEAQRNISEPGVIFRCYFESGNNCSPYNIDTKGNY 99
            :|.||.:        ::..|::....::.|.:.|:.|.|         ...:..:.|.|...|.|
Zfish   260 QGGRRGA--------KKVMIVITDGESHDSADLQQVIEE---------SEKDGITRYAIAVLGYY 307

  Fly   100 --KGMPNDGLLTAKNKDFRWLGGAMDGGTRDSDKFLVCAPRFYSINNEN------DYNNGMCYWL 156
              :|:..:..|    .:.:::....|      ||      .|:::.:|.      |......:.|
Zfish   308 NRRGINPEAFL----NEIKYIASDPD------DK------HFFNVTDEAALKDIVDALGERIFSL 356

  Fly   157 SDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIPYYSMGELGLSAHVSDDNSKLLMGAPGIDQW 221
            ..|.||..:..:                         .|.:.|.|.|..:|.  :|:||.|...|
Zfish   357 EGTSKNGTAFGL-------------------------QMSQAGFSTHTVEDG--ILVGAVGAYDW 394

  Fly   222 KGSVHLKQEVPSIKTSSGRQRRGMNTNRKCN---ECNPEPKNFGQEEFSYFGYAVSSGYFDSSNL 283
            .|:| ||:           .|:|.....|.:   |...|.||.|    :|.||.|:|..   |..
Zfish   395 NGAV-LKE-----------TRQGKVVPPKSSYEQEFPEELKNHG----AYLGYTVTSVV---SAR 440

  Fly   284 STVLYVATAPRGNNQFGEAYIFDIYE-DSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTD-VII 346
            |..||||.|||.|:. |:..||.:.. ..:...|..:|...|.|:|..:...|::.||.|| :::
Zfish   441 SGQLYVAGAPRFNHT-GKVIIFTLKNTGELTILHSLKGQQIGSYYGSEIAPVDIDNDGVTDNLLV 504

  Fly   347 SAPLYALRNSYDDGAIYV--------FINKGSFTFEERIIRSPAGSGGRFGTTLSRIGDINKDGY 403
            :||:: ....::.|.:|:        ||.:||....::      |...|||:.|:.:.|:|.|.:
Zfish   505 AAPMF-FSGGWEKGKVYIYRVTEQPRFILEGSLEVLDQ------GQNARFGSALAPVPDLNGDSF 562

  Fly   404 NDVAVGAPFAGN--GSVFIYLGSENGLRDPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGF 466
            |||.||||...:  |:::||....|.:.....|.:.|....|   |...||..:....|::|:..
Zfish   563 NDVVVGAPLEDDHKGAIYIYHSQRNRILRKYKQRIGAVQLGP---GLQYFGRSIHGKMDMNGDDL 624

  Fly   467 NDFAIGAPNAEAVYLYRAYPVVKIHAIIK---PKLQNVNPEEER-------VNITVCYRLSSKSD 521
            .|.|:|:..| ||.|: :..|::|:::::   .|:...|.:..|       ::..||..::|::.
Zfish   625 VDLAVGSLGA-AVLLW-SRSVIRINSVVRFEPSKINIFNKDCRRGGKDVTCMSAIVCLNVTSRTP 687

  Fly   522 SKAKALMEQELVIRID--IDTKSKIKLAVFDEEHGSQMSFKAKAFHEEICSEFQIEMDKRAKFT- 583
            ...    .||:.:|..  .:.|.....||||:....|.........||.|......:.:...:.
Zfish   688 INP----SQEIALRYSAFFEEKRFNPRAVFDDPDRQQPQNLTLLPGEETCDHIYFHVMETTDYAR 748

  Fly   584 PIALEMQYELSKKIPNSGDFCEDCAVVDPAEPKFVTEYITFNTGC-ATDVCVADL---------- 637
            ||...::.||......        .|:|.:.|..|...:.|..|| ..|.||.||
Zfish   749 PIIFTVETELLDLYHG--------PVLDDSWPTTVKTQLPFWNGCDEDDHCVPDLLLQAHTDLMN 805

  Fly   638 ------------KISCINASST-----LVLGTTAVLRLTYNITNNGEFAYHPKFSVTNSAGLSLA 685
                        .:.|...:||     ::.|:...:.:...:.|.||.||..|.::|.:..|..:
Zfish   806 RQQFCGQAFRAASLLCQGHTSTDPSERIIEGSRRKMVVDVRLENRGENAYGAKLNITYTQNLRFS 870

  Fly   686 Q--VPGN------------------CKVNEAVMVC----------DLNHGQRMAKGDTDSLTISF 720
            .  |..|                  |.::|..|..          :.:|.:.:     |.:.|..
Zfish   871 SLIVKDNSDIHIDCRNENKRKYEKTCNISEPFMRAKSQVIFRLEFEFSHSELL-----DHVRIIL 930

  Fly   721 DVRQ------LRGRSLEI------QAEVLSARDESNPENNKLTNVLSLREKADIYVSGVQTNDHV 773
            :|..      |...|.||      :|::|..|| ..|...:|...||| ||||.:
Zfish   931 EVTSEGEEVILYDNSNEIFYNLKYEADLLFTRD-FYPTRYELKPDLSL-EKADDF---------- 983

  Fly   774 VLKESPYTAEVVNY-YEIKSHGPSTLENLTVSLYIPVAYKTPDSTNVKHIVTSSPKIQSKYAHKI 837
               ..|:     |: ::|::.|...:::|  .|||.:                 |:: :|..:::
Zfish   984 ---NPPF-----NFTFQIQNLGYFPIQDL--QLYIAI-----------------PEV-TKNGNQL 1020

  Fly   838 MPINFIDQNNALANNFAIDHDQSTLLFSATPQHENVGNLSGIVEQNPSISLLNEDLPVNNTLVLN 902
            :.|          .:|.||....:...  .|||  |.:.....|.....|.||    .:|||.:.
Zfish  1021 LQI----------RDFHIDQIGGSQCI--PPQH--VAHSRASPEDLSRTSRLN----YSNTLAVP 1067

  Fly   903 CQDT-------NVTLCVPVEIRLE--NGLQLKPEELMNMTVSFTVNLKDADDIWEYFVIQTDLKV 958
            .|.|       :|::.:...:|.:  :.|:.|..||:. |.|..:|
Zfish  1068 VQCTVNLPSYRDVSVKIGGSLRTDALHALKFKTLELVT-TASVELN------------------- 1112

  Fly   959 HKIGDPTLSSFTIEKKIESNVIC-----KHAEIAIWKIIVSVIVGILVFSAATYALYKRGFFKRA 1018
                 |:...|..|::...::|.     :...:.||.||.|.:.|:|:.|....||:|.|||:|
Zfish  1113 -----PSSPMFLPEERPVRHIILEIRKEEDYRVPIWIIIGSTLGGLLLLSLLILALWKLGFFQR- 1171

  Fly  1019 IKDDLKQLIRDSFEDGIIRTEMEE 1042
                  |..|:..|:.:....|||
Zfish  1172 ------QKRREEAENEVNGKTMEE 1189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	24/81 (30%)
		Int_alpha	384..434	CDD:214549	18/51 (35%)
		Int_alpha	447..>492	CDD:214549	14/44 (32%)
		Integrin_alpha2	486..808	CDD:462478	81/405 (20%)
itga11a	NP_001166098.2	None