Protein Alignment ItgaPS4 and itga2b

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001003857.1
• Gene: itga2b / 445380
• ZFINID: ZDB-GENE-051031-1
• Length: 1037
• Species: Danio rerio
• Alignment Length: 1122
• Identity: 279/1122 - (24%)
• Similarity: 483/1122 - (43%)
• Gaps: 219/1122 - (19%)

  Fly     2 FCLLVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLVI-----REKSIMVAAPRA 61
            |.||.:.:|...:.|..:|:.....:|.:.||      .||||||:..     :..|::|.||||
Zfish     7 FSLLFLSILIFTNHIRGFNLDLNQYTVFSGPE------DSYFGFSVDFYQSSSKSVSVVVGAPRA 65

  Fly    62 NSSLEAQRNISEPGVIFRC-YFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGG 125
            |::   |..:|..|.:|.| :...|.:|...|.|.||: :.:....:|...:|..:|||.::
Zfish    66 NTN---QSGVSHGGSVFMCPWATRGQSCQTLNFDQKGD-ENITFGNMLLMAHKSNQWLGASV--- 123

  Fly   126 TRDSDKF-LVCAPRFY---SINNENDYNN--GMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKL 184
             |..:.: |.|||.|:   .::.|...|.  |.|..|     |:.:.|:....|.|.|....:
Zfish   124 -RTYNNYILACAPLFHWNVLVDQEEAMNTPVGNCQLL-----NMKTGELANYAPCREEYVYAI-- 180

  Fly   185 ADTNLIPYYSMG-------ELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKT-SSGRQ 241
                    |:.|       |.|.:..:: .|.::::||||...::|.:.....|..:.: ||...
Zfish   181 --------YTRGYPDRRYCEAGFTTDIT-KNGRVVLGAPGGYYFQGQIITASLVNIMSSGSSFTP 236

  Fly   242 RRGMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIFD 306
            :..||...|    .|:.:::..   .|.||:|::|.|::.|:..  ||...|...:..|...|.:
Zfish   237 KHSMNGETK----TPQRRDYYD---LYLGYSVAAGKFNNDNIPD--YVVGVPNDLHTAGSVKIIN 292

  Fly   307 IYEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLY----ALRNSYDDGAIYVFIN 367
            .....:.......|.....|||:||...|:|.||..|::|.|||:    :.:...:.|.:||::.
Zfish   293 GATVPLQIMKAISGTQIASYFGHSVAVTDINRDGWDDILIGAPLFMEQLSTQKFREVGQVYVYLQ 357

  Fly   368 KGSFTFEERIIRSPAG--SGGRFGTTLSRIGDINKDGYNDVAVGAP-FAGNGSVFIYLGSENGLR 429
            :..|:|..|..:..||  :.||||:.::.:||::.||:|||||||| ....|.||||||...||.
Zfish   358 RNDFSFASRPNQILAGTYAYGRFGSAIAPLGDLDHDGFNDVAVGAPGSVDGGKVFIYLGKSGGLS 422

  Fly   430 DPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKIHAII 494
            ....|.:::|.:  |.....|||..:..|:|||.||:.|..|||..|..|..|||..||:..|.:
Zfish   423 TQYVQVIESPFR--SLIDPPMFGFSIRGGTDIDDNGYPDLIIGAWGASKVVTYRAQAVVRTQARL 485

  Fly   495 K--PKLQNVNPEEE------------RVNITVCYRLSSKSDSKAKALMEQELV----IRIDIDTK 541
            .  |.|  :|||::            ...|..|.|:|...       :.|::|    :::|...:
Zfish   486 SFFPDL--LNPEDKFCQLQQSGTYITCFTIMACIRVSGHR-------IPQQIVFNTELQLDRMKQ 541

  Fly   542 SKIKLAVFDEEHGSQMSFKAKAFH--EEICSEFQIEM--DKRAKFTPIALEMQYELSKKIPNSGD 602
            |..:..:..:.:....:|:.....  .::|..|...:  :.:.|.:||.:.:.|.|:.
Zfish   542 SMARRTLLLDSNQPYTNFQISVDRNSRDVCRNFTAYLLPEFKDKLSPIFISVNYSLAD------- 599

  Fly   603 FCEDCAVVDPAEPKFVTEYITFNTGCATDVCVADLKISCINASSTLVLGTTAVLRLTYNITNNGE 667
              ...||:...........|..|.| ..:||:.||::..:.::..:::|......|.....|.||
Zfish   600 --SQNAVLHGQSVAVGQTRIILNCG-PDNVCIPDLQLKAVTSTEPILIGDENPALLIIEAENQGE 661

  Fly   668 FAYHPKFSVTNSAGLSL-----------AQVPGNCKVN-EAVMVCDLNH----GQRMAKGDTDSL 716
            .||..:..::..|....           |.|.|..|.| ..::||||.:    ||::..|    |
Zfish   662 GAYETELYISPPANTHYQGVLSNHEDFSALVCGQKKENGSVIVVCDLGNPLEAGQQLKAG----L 722

  Fly   717 TISF-DVRQLRGRSLEIQAEVLSARDESNPENNKLTNVLSLREKADIYVSGVQTNDHVVLKESPY 780
            ..|. |:.|:... :..|.::.| ::..|.::|.:...:::...|.:.:.||.:....||..|.:
Zfish   723 YFSMGDLEQVENH-ITFQMQIRS-KNSQNSDSNLVQLQVNVTAVASLEMRGVSSPVDCVLPISKW 785

  Fly   781 TAE------------VVNYYEIKSHGPSTLENLTVSLYIPVAYKTPDSTNVKHIV----TSSPKI 829
            .::            :.:.||:::.|||.: |:.::|..||      |.|..:::    .:|.::
Zfish   786 ESKDYPEDLDEVGPLIEHVYELRNRGPSPV-NVKLTLEFPV------SQNESYLLYVFANASEEL 843

  Fly   830 ---QSKYAHKIMPINFIDQNNALANNFAIDHDQSTLLFSATPQHENVGNLSGIVEQNPSISLLNE 891
               |:.||: |.|...:.|             :||.:..|...|.|..:||...|        ||
Zfish   844 ISCQTDYAN-IDPRRLVKQ-------------ESTNITVAEVHHFNKRDLSQKTE--------NE 886

  Fly   892 DLPVNNTLVLNCQDTNVTLCVPVEIRLENGLQLKPEELMNMTVSFTVNLKDADDIWEYFVIQTDL 956
            . ...:|:.:||..:.  .||..:. :..|||.....::.:          ...:|    :||.|
Zfish   887 Q-QWQHTVHVNCSSSE--QCVVFDC-VAAGLQRDERAIVRV----------MSRLW----VQTFL 933

  Fly   957 K---VHKIGDPT--LSSFTIEKKIESNVICK----------------HAEIAIWKIIVSVIVGIL 1000
            |   |:.:...|  .....:..||:.:|:..                ..|:.:|.|:||::.|:|
Zfish   934 KRPYVNYVLHSTAHYEVMNVPSKIQPDVLPTGKAETHTKIIWRSPDGQEEVPLWWIVVSIVAGLL 998

  Fly  1001 VFSAATYALYKRGFFKR 1017
            :.:|.:...:|.|||||
Zfish   999 LLAALSTIFWKMGFFKR 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	28/78 (36%)
		Int_alpha	384..434	CDD:214549	25/50 (50%)
		Int_alpha	447..>492	CDD:214549	20/44 (45%)
		Integrin_alpha2	484..808	CDD:285619	75/374 (20%)
itga2b	NP_001003857.1	Int_alpha	256..>293	CDD:214549	12/38 (32%)
		Int_alpha	309..>358	CDD:214549	17/48 (35%)
		Int_alpha	376..429	CDD:214549	26/52 (50%)
		Int_alpha	441..>480	CDD:214549	19/38 (50%)
		Integrin_alpha2	475..908	CDD:285619	101/489 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574943
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740