Protein Alignment ItgaPS4 and itga3a

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_017210291.1
• Gene: itga3a / 407685
• ZFINID: ZDB-GENE-090805-3
• Length: 1073
• Species: Danio rerio
• Alignment Length: 1192
• Identity: 273/1192 - (22%)
• Similarity: 463/1192 - (38%)
• Gaps: 268/1192 - (22%)

  Fly     4 LLVIVLLALQSEINAYNISPYPNSVLNFPEL-EGNRRSSYFGFSLVIREK-------SIMVAAP- 59
            |.::.:|:......|:|:.      ::|..: ||....|.||.|:.:.|:       .::|.||
Zfish    11 LTLVFVLSAARLCQAFNLD------VSFAVVKEGKTAGSLFGLSVALHEQVVNEKRHMLLVGAPK 69

  Fly    60 -RANSSLEAQRNISEPGVIFRCYFES-GNNCSPYNI-----DTKGNYKGMPNDGLLTAKNKDFRW 117
             :|.|.|.|    :|.|.::.|...: ..:|:..|:     :.|.:.|....||:         |
Zfish    70 EKAESGLSA----NETGDVYACPISADSKDCARLNLISSNPEDKPDLKNYVIDGM---------W 121

  Fly   118 LGGAMDGGTRDSDKFLVCAPRFYSINNENDYNNGMCYWL-SDTPKNIDSTEVMEKW--------P 173
            ||.::...::...:.:.|..|:......|....|.||.. :|...|:...:    |        |
Zfish   122 LGVSIVSQSQPGGRVVACGHRYIRNFTSNFRMIGRCYVRGNDLQLNLSDYQ----WQSYDEICDP 182

  Fly   174 LRIEKKQVLKLADTNLIPYYSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPS----- 233
            ...:..:.:.|             ||:||.|:  .|::..||||...|:|::..|...|:
Zfish   183 REAQNSEGMCL-------------LGMSAAVT--FSEIFFGAPGCFNWQGNIFSKWHNPADEFHL 232

  Fly   234 IKTSSGRQRRGMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNL----STVLYVATAPR 294
            :|:.....|:|               |.      |.||   |...|...|    .||  |..|||
Zfish   233 LKSKLPDSRKG---------------NI------YIGY---STIVDQDVLVKGKDTV--VTGAPR 271

  Fly   295 GNNQFGEAYIFDIYED----SIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRN 355
            ...: |...:.::.:.    .:.......|...|.|||.||...|||.||..|:|:.||.|..|.
Zfish   272 DEAK-GSVMMAEVLKSGGSGEVKIKVTVTGEQVGSYFGNSVAVVDLNNDGWKDLIVGAPFYFDRK 335

  Fly   356 SYDDGAIYVFINK-GSF-TFEERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAGNGSV 418
            ....||:||::|: ||| ...:.::..|..||  ||.::..|||:|:||:.|.|||||:...|.|
Zfish   336 MDKGGAVYVYMNQNGSFRNKSDVVLTGPKDSG--FGMSVVAIGDVNQDGFQDFAVGAPYHSTGRV 398

  Fly   419 FIYLGSENGLRDPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYR 483
            .|:.||:.|:...|||.:|.......  |...||:.:|||.|:|.||:.|.|:|:.: :.|.|.|
Zfish   399 SIWTGSKTGISQEPSQVIDGKDIPGG--GFQTFGYSISRGLDVDRNGYPDIAVGSLD-DRVVLLR 460

  Fly   484 AYPVV--KIHAIIKPKLQNVNPEEERVNITVC--YRLSSKSDSKAKALMEQELVIRIDIDTKSKI 544
            :.||:  |....:.|.:.|:......:...||  |..|:.:.|..||:..| ..:..|..:....
Zfish   461 SRPVIHLKNTFTVTPMVINLEDCVACIEAKVCFSYTYSTGTASSQKAVTLQ-YTVEADQQSSRSP 524

  Fly   545 KLAVFDEEHG---SQMSFKAKAFHEEICSEFQIEMDKRA---KFTPIALEMQYELSKKIPNSGDF 603
            :::..|...|   .:||.....    .|...::|:..:.   |.:.|..::...:....|:.|..
Zfish   525 RVSFLDNNKGKYTGKMSVNPSG----DCHSLKLELASKTIQDKVSAIIFQLSVSVVDPPPSGGKM 585

  Fly   604 CEDCA---VVDPAEPKFVTEYITFNTGCATD-VCVADLKISC-----------INASSTLVLGTT 653
            .||.:   |:...:.......|.....|..| .|.::|:::.           :.....:...||
Zfish   586 LEDLSAFPVISQRDALTGRAEIHIQKACGLDNKCESNLQMTAAFTDEKNTPFLMQEDHQIFNYTT 650

  Fly   654 AV--LRLTYNITN------NGEFAYHPKFSVTNSAGLSLA----QVP----GNCKVNEAVMVCDL 702
            .:  |:|..|::|      ..|.||:...::|..:.||.:    ::|    |:.....:.::|.|
Zfish   651 DIKKLKLLVNVSNVPSEGRKAEDAYNAILNITIPSSLSFSSLNPKLPSTLNGDPSSGGSYLLCTL 715

  Fly   703 ----NHGQRMAKGDT-DSLTISFDVRQLRGRSLEIQAEVLSARDESNPENNKLT----------- 751
                ...||:....| ::..||.|::::   ..|:|...||.:::..|.:..|.
Zfish   716 GDPFKSNQRVEIEITFETSGISIDMQEI---ETELQLSTLSDQNDLRPLSRVLLVEYILQPLFNL 777

  Fly   752 ----------NVL---SLREKADIYVSGVQTNDHVVLKESPYTAEVVNYYEIKSHGPSTLENLTV 803
                      ||:   :::..:|| .|.|:.|..|.:...|...  :.:.|:....||.:.|...
Zfish   778 IPYFRAEFSGNVVGESAMKSTSDI-GSPVEFNISVDISGKPLGN--LGFLEVVFQWPSAVANEKW 839

  Fly   804 SLYIPVAYKTPDS---------TNVKHIVTSSPKIQSKYAHKIMPINFIDQNNALANNFAIDHDQ 859
            .||:.....|..|         .|..::..|..|.:.:...:::                   .:
Zfish   840 LLYLSEIQMTGTSESFCVAKGIVNPLNLTVSERKSRRRKRDEVL-------------------SE 885

  Fly   860 STLLFSATPQHENVGNLSGIVEQNPSISLLNEDLPVNNTLVLNC--QDTNVTLCVPVEIRLENGL 922
            |.|..|   |....|       ||....:||...........:|  .....:..:.|..|:.|..
Zfish   886 SKLAMS---QKTRQG-------QNKPREVLNCTKGTARCQTFSCPLSAMKTSAMLTVRARVWNST 940

  Fly   923 QLKPEELMNMTVSFTVNLKDADDIWEYFVIQTDLKVHKIGDPTLSSFTIEKKIESNVICK-HAEI 986
            .|:......::|..:|.|          .::||.|..|:.: .:..||:|  |:..|..: ..|.
Zfish   941 MLEDYRAKGVSVQGSVML----------TLKTDKKNIKMNN-NIREFTVE--IDPAVAEELPYEA 992

  Fly   987 AIWKIIVSVIVGILVFSAATYALYKRGFFKRAIKDDLKQLIRDSFE-----DGIIRTEMEENAQS 1046
            .:|.|||||:.|:::.......|:|.|||.|.          |.|.     .|:...:.|:...:
Zfish   993 PLWIIIVSVLSGVVMLGVIVILLWKSGFFTRI----------DYFRAMPKYKGVRICKKEQYQVN 1047

  Fly  1047 QGDADLDEKLDAYADTTGKCTH 1068
            ||...|        |||....|
Zfish  1048 QGFLIL--------DTTNNRKH 1061

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	31/74 (42%)
		Int_alpha	384..434	CDD:214549	23/49 (47%)
		Int_alpha	447..>492	CDD:214549	19/46 (41%)
		Integrin_alpha2	484..808	CDD:285619	75/393 (19%)
itga3a	XP_017210291.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574940
Domainoid	1	1.000	61	1.000	Domainoid score	I10420
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740