Protein Alignment ItgaPS4 and itga9

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001311427.1
• Gene: itga9 / 394012
• ZFINID: ZDB-GENE-040426-1129
• Length: 1032
• Species: Danio rerio
• Alignment Length: 1187
• Identity: 293/1187 - (24%)
• Similarity: 486/1187 - (40%)
• Gaps: 313/1187 - (26%)

  Fly     6 VIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLV--IREKS--IMVAAPRANSSLE 66
            |.|.|...|...::||.      |.:|.:.....:::||:|::  :.:.:  |:|.|||||||..
Zfish    18 VFVCLCSVSLAYSFNID------LQYPVVFRGPDATFFGYSVLEHVHDNTRWIVVGAPRANSSFS 76

  Fly    67 AQRNISEPGVIFRCYFESG--NNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGGTRDS 129
            :  ::..||.:::|...:.  ..|:..::. :|| |...:.|.....:::..|:|.::....:.:
Zfish    77 S--SVQSPGAVYKCRIRNNPEQRCTEMDLG-RGN-KQRESCGKTCQGDRNDEWMGVSLARQNKPN 137

  Fly   130 DKFLVCAPRFYSINNENDY--NNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIPY 192
            .|.|.||.|:.::..|::|  .:|.|   |..|.|:..            |.|       .|||.
Zfish   138 GKILACAHRWKNVYYESEYILPHGYC---SIIPANLQG------------KSQ-------PLIPC 180

  Fly   193 Y-----SMGE------LGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRGMN 246
            |     :.||      .|::...:::  .::|||||...|.|:|.:..     .||        |
Zfish   181 YEDHKKTYGEEHGSCQAGIAGVFTEE--LVVMGAPGSYYWTGTVKVFN-----MTS--------N 230

  Fly   247 TNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIFDIYEDS 311
            |:...|:.:..|     ..:||.||||::|:|.|.|  |:...|.||:.:.. |:.|:|.|...:
Zfish   231 THYNLNQDDLSP-----HRYSYLGYAVTAGHFSSPN--TIDVAAGAPQDSGG-GKVYVFRIEGTA 287

  Fly   312 IYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYA-LRNSYDDGAIYVFINKGSFTFEE 375
            :.|..:..|...|.|||.|:.|.|||.||.:|:::.||::: :|   |:|.:.|:::.|:...||
Zfish   288 LVKIFQASGKMMGSYFGSSLCAVDLNADGLSDLLVGAPMHSEIR---DEGQVSVYLSSGNGVMEE 349

  Fly   376 -RIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAGN--GSVFIYLGSENGLRDPPSQCLD 437
             .|:.........||..::.:|||:.|||.|||:|||...:  |:|:||.|...|:.:..|..|.
Zfish   350 VAILNGDNAYNAHFGECITSLGDIDDDGYQDVAIGAPEEDDYGGAVYIYHGDARGIVNKYSMRLS 414

  Fly   438 APSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKIH-AIIKPKLQNV 501
            ..|..|:   ..|||..:|...|:||||:.|..|||..|::|.|.|:.||:.:. :|..|...|:
Zfish   415 GRSINPT---LQMFGQSISGNVDMDGNGYPDVTIGAFMADSVVLLRSRPVISVDVSIFLPVSINI 476

  Fly   502 -------NPEE-ERVNITVC---------------YRLSSKSDSKAKALMEQELVIRIDIDTKSK 543
                   .|:. ...|:|||               |.|::.||.:.|.|..:
Zfish   477 TVPQCHEGPQHLNCFNVTVCMSFRGKHVPGHIELLYNLTADSDKRHKGLPPR------------- 528

  Fly   544 IKLAVFDEEHGSQMSFKAKAF----HEEICSEFQIEMDKRAK--FTPIALEMQYELSKKIPNSGD 602
               |.|. ..|.|....::.|    |.:.|.::...:.|..|  |..|..|..|.|.|.|.:...
Zfish   529 ---AYFG-NGGEQTGVVSQRFNLEIHRQQCHQYTAFVRKEVKDVFAAIVFEAAYSLGKHIVDEHQ 589

  Fly   603 FCEDCAVVDPAEP--------KFVTEYIT-FNTGCATDVCVADLK------ISCINASSTLVLGT 652
            ..:    :.|..|        |...:..| |...|.:|.|.|||:      :|....||.|.||.
Zfish   590 DRD----LPPLSPILRWKKGEKIAAKNETWFEKNCLSDDCAADLQLHGKLLLSGRYISSHLALGG 650

  Fly   653 TAVLRLTYNITNNGEFAYHPKFSVTNSAGLSLAQVPGNCKVNEAVMVCDLNHGQRMAKG------ 711
            ...:.|...|:|.|:.||..                 |...|.:..|..:|..||..||
Zfish   651 VKNVSLNLTISNAGDDAYDT-----------------NIYFNFSKEVHYINFLQREEKGISCMLV 698

  Fly   712 DTDSLTIS-----------------FDVRQLRGRSLEIQAEVLSARDESNPE------NNKLTNV 753
            :.|.|..|                 ||..:|.|.: |....::.|| .:|||      :|.|...
Zfish   699 ELDFLKCSVGFPFMRAQTKYHISALFDTSRLSGEN-ETLLFLVHAR-SANPEHDNTLHDNTLELS 761

  Fly   754 LSLREKAD------------IYVSGVQTNDHVVLKESPYTAEVVNY-YEIKSHGPSTLENLTVSL 805
            :.|..:.|            :|.:.|..:..|.|::...:.:.:|: :::.::|||.|....|.:
Zfish   762 IPLVHEVDTTITGVVNPTSFVYGNSVDRSRFVQLEDMECSFQPLNFTFQVINNGPSRLPGSRVDI 826

  Fly   806 YIPVAYKTPDSTNVKHIVTSSPKIQSKYAHKIMPINFIDQNNALANNFAIDHDQSTLLFSATPQH 870
            .||           ..:..|.|::          .:.||                      |...
Zfish   827 RIP-----------HRLAGSGPEM----------FHIID----------------------TQVS 848

  Fly   871 ENVGNLSGIVEQNPSISLLNEDL-PVNNTL----------VLNCQDTNVTLCVPVEIRLENGLQL 924
            :..||.:.  .:||....:.:|. .:.:|:          ||:| |.....|:.:...|  |.|.
Zfish   849 DARGNCTW--HRNPKPCTIPQDKESIFHTIFAFFTKSGRKVLDC-DRPGRACLTISCSL--GSQA 908

  Fly   925 KPEELMNMTVSFTVNL----KDADDIWEYFV---IQTDLKVHKI--GDPTLSSFTIEKKIESNVI 980
            | ||..::.|...:|.    :|:..:.::..   :|.|.:..::  |.|...|..:|
Zfish   909 K-EEATSIDVQMLLNTEILQRDSSSVIQFVTRGHVQLDDRTVEVSSGLPDDISLVME-------- 964

  Fly   981 CKHAE-----IAIWKIIVSVIVGILVFSAATYALYKRGFFKRAIKDDLKQLIRDSFEDGIIRTEM 1040
            ..|::     :..|.|.:|::||||:|......|:|.|||:|..::.:               |.
Zfish   965 ALHSQEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRHYREII---------------EA 1014

  Fly  1041 EENAQSQGDADLDEKLD 1057
            |:|.:     |.||..|
Zfish  1015 EKNRK-----DSDESWD 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	26/74 (35%)
		Int_alpha	384..434	CDD:214549	20/51 (39%)
		Int_alpha	447..>492	CDD:214549	19/45 (42%)
		Integrin_alpha2	486..808	CDD:462478	90/408 (22%)
itga9	NP_001311427.1	Int_alpha	45..93	CDD:214549	15/49 (31%)
		Int_alpha	245..293	CDD:214549	19/50 (38%)
		Int_alpha	299..345	CDD:214549	19/48 (40%)
		Int_alpha	360..413	CDD:214549	21/52 (40%)
		Int_alpha	423..>465	CDD:214549	19/41 (46%)
		Integrin_alpha2	459..907	CDD:462478	110/535 (21%)