Protein Alignment ItgaPS4 and ItgaPS5

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Alignment Length: 1075
• Identity: 505/1075 - (46%)
• Similarity: 693/1075 - (64%)
• Gaps: 108/1075 - (10%)

  Fly     1 MFCLLVIVLLALQSEINAYNISPYPNSVLNFPELEGNR----RSSYFGFSLVIREKSIMVAAPRA 61
            |..||.::.|||:.:.||.|.||.||.|::.|:....|    ||||||:|||||..||.|.||||
  Fly     1 MHRLLFLIFLALKYQSNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLVIRPTSIFVGAPRA 65

  Fly    62 NSSLEAQRNISEPGVIFRCYFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGGT 126
            .|:||:|.:|:|.|.::||...|| :||.|.:          ||.|    ||.|:||||:|||||
  Fly    66 QSTLESQGSINETGAVYRCPLASG-SCSHYVL----------NDKL----NKQFQWLGGSMDGGT 115

  Fly   127 RDSDKFLVCAPRFYSINNENDYN--NGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNL 189
            :|:||.|||||||:...|:| |.  .|:|||:.||        |.:..||.       .:...:|
  Fly   116 KDTDKLLVCAPRFFVPKNKN-YGQMRGICYWVRDT--------VADTPPLS-------DVRTISL 164

  Fly   190 IP----YYSMGELGLSAHVSDDNSKLLMGAPGIDQWKGS--VHLKQEVPSIKTSSGRQRRGMNTN 248
            ||    .:.|.||||||||:||||..|:||||:..||||  ||..:::.:         :|....
  Fly   165 IPSQAEEHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGEDLAA---------QGSYAV 220

  Fly   249 RKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIFDIYEDSIY 313
            :..:..     ::.:..|:|.|||:|||||.|:|.:::|||.|||......|:|||||:..:.:.
  Fly   221 KMLDSW-----DWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDVVGEIVR 280

  Fly   314 KYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRNSYDDGAIYVFINKGSFTFEERII 378
            |.|.|.|...||||||||:||||||||.|||::||||.||.:|||.||||||||||.|.||::||
  Fly   281 KLHVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSYDVGAIYVFINKGLFKFEKKII 345

  Fly   379 RSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAGNGSVFIYLGSENGLRDPPSQCLDAPSQQP 443
            |.|..||.|||::||::||||.|||||:||||||||||:|||:||||:||||.|||.|||||::|
  Fly   346 RLPLSSGARFGSSLSKVGDINHDGYNDLAVGAPFAGNGAVFIFLGSEHGLRDEPSQRLDAPSREP 410

  Fly   444 SKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKIHAIIKPKLQNVNPEEERV 508
            ..||::|||.|||||||||||||||.|||||.|||||||||||||||||.::.:.:.:.||:|.:
  Fly   411 GPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVRSESRAIRPEQETI 475

  Fly   509 NITVCYRLSSKSDSKAKALMEQELVIRIDIDTKSKIKLAVFDEEHGSQMSFKAKAFHEEICSEFQ 573
            .:|.||||  ::.|||:.:.:|||..|:.||  ..::...|.....:::||:|:|.....|..|.
  Fly   476 TVTACYRL--ETTSKARQMQQQELTFRMTID--ELLQRVSFAPMRTNEVSFQAQAGLSGSCRNFS 536

  Fly   574 IEMDKRAK-FTPIALEMQYELSKKIPNSGD-FCEDCAVVDPAEPKFVTEYITFNTGCATDVCVAD 636
            :.:..... ||||.||:.|||:||||:|.: |||.||||||.|||:.|..::|.||||..|||:|
  Fly   537 VGVHYTGGIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKYATGTLSFMTGCAAHVCVSD 601

  Fly   637 LKISCINASSTLVLGTTAVLRLTYNITNNGEFAYHPKFSVTNSAGLSLAQVPGNCKVNEAVMVCD 701
            |::|..:.:|:.:.|:..||..:|.|||:||.||..:|:||:||.|..|:|||||:|...||:||
  Fly   602 LQLSSKDVNSSFIFGSLEVLSFSYEITNSGEPAYVAQFNVTSSARLPFAKVPGNCRVRHEVMLCD 666

  Fly   702 LNHGQRMAKGDTDSLTISFDVRQLRGRSLEIQAEVLSARDESNPENNKLTNVLSLREKADIYVSG 766
            ||.|:.:|:||::||||.|||.||.|:||.|:|.|.||..:.||::|.::..:||||.|:|..||
  Fly   667 LNGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSAGMDQNPKDNTMSTTISLREYAEIDASG 731

  Fly   767 VQTNDHVVLKESPYTAEVVNYYEIKSHGPSTLENLTVSLYIPVAYKTPDSTNVKHIVT-SSPKIQ 830
            ...:.|:.|||.||:|||.|.||.||||||.::.|||.:.:|:||....|..:|.|.. ||.::|
  Fly   732 GPIDGHIALKEYPYSAEVNNSYEFKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQ 796

  Fly   831 SKYAHKIMPINFIDQNNALANNFAID--------------HDQSTLLFSATPQHENVGNLSGIVE 881
            :.:..:::||...||.|.||..:.::              .||..::...        |:|.|
  Fly   797 ATHGSELVPIKLYDQTNTLAKEYPLEDSSRRANRKRRELQQDQYAIMPDV--------NISDI-- 851

  Fly   882 QNPSISLLNEDLPVNNTLVLNCQDTNVTLCVPVEIRLENGLQLKPEELMNMTVSFTVNLKDADDI 946
                  |..|:||.|.||||:|...|.|:||..::|    :|||||:.:::.:||.|:|.|..:.
  Fly   852 ------LTKENLPANRTLVLDCLRGNWTICVRSQMR----VQLKPEQPIDLRISFKVDLNDFVNT 906

  Fly   947 WEYFVIQTDLKVHKIGDPTLSSFTIEKKIESNVICKHAE--IAIWKIIVSVIVGILVFSAATYAL 1009
            ::|.||.|::::.|.||.|  |..:::.::.|||..::|  :.||.||:|:|.|.|:..|.||.|
  Fly   907 FDYLVIFTNVEMFKEGDST--SIALKRNLKPNVIFNYSETPLPIWYIILSLIAGHLLLGAMTYIL 969

  Fly  1010 YKRGFFKRAIKDDLKQLIRDSFEDGIIRTEMEENA 1044
            ||..||||..|::||:|:.:.      |:|.:|.|
  Fly   970 YKLRFFKRGKKEELKRLLEEH------RSETKEPA 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	51/72 (71%)
		Int_alpha	384..434	CDD:214549	38/49 (78%)
		Int_alpha	447..>492	CDD:214549	39/44 (89%)
		Integrin_alpha2	486..808	CDD:462478	153/323 (47%)
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	29/37 (78%)
		Int_alpha	351..403	CDD:214549	40/51 (78%)
		Int_alpha	417..463	CDD:214549	40/45 (89%)
		Integrin_alpha2	453..837	CDD:462478	169/387 (44%)