Protein Alignment ItgaPS4 and Itga8

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001167443.1
• Gene: Itga8 / 364786
• RGDID: 621634
• Length: 1062
• Species: Rattus norvegicus
• Alignment Length: 1140
• Identity: 299/1140 - (26%)
• Similarity: 485/1140 - (42%)
• Gaps: 216/1140 - (18%)

  Fly     3 CLLVIVLLALQSEIN-AYNISPYPNSVLNFPELEGNRRSSYFGFSLVI-----REKSIMVAAPRA 61
            |.:..||..|.|.:: |:|:.....:|.:.||      .||||:||..     |..|::|.||:|
  Rat    21 CCVSAVLGMLWSPVSLAFNLDVDKLTVYSGPE------GSYFGYSLDFYIPDARTASVLVGAPKA 79

  Fly    62 NSSLEAQRNISEPGVIFRCYF--ESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDG 124
            |:|   |.:|.|.|.::.|.:  |....|.....||..|.|...|......:.|..:|.|..:
  Rat    80 NTS---QPDIVEGGAVYYCPWPAERSAQCKQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATV-- 139

  Fly   125 GTRDSDKFLVCAPRFY----SINNENDYNNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLA 185
             .....|.:.|||.::    ..|...| ..|.||....     :.:...|..|.|
  Rat   140 -RAHKGKVVACAPLYHWRTLKPNPAKD-PVGTCYVAIQ-----NFSAYAEHSPCR---------- 187

  Fly   186 DTNLIPY---YSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRGMNT 247
            ::|:.|.   |......|..:   .|..|::|.||...|:|.|........|...|.:.......
  Rat   188 NSNVDPEGQGYCQAGFSLDFY---KNGDLIVGGPGSFYWQGQVITVSVADIIANYSFKDILRKLA 249

  Fly   248 NRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIFDIYEDSI 312
            ..|..:..|     ...:.||.||:|::|.|...:|..:  ||..|||...||  |:..|....:
  Rat   250 AEKQTDVAP-----ASYDDSYLGYSVAAGEFTGDSLQEL--VAGIPRGAQNFG--YVSIINSTDM 305

  Fly   313 YKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALR----NSYDDGAIYVFINKGSFTF 373
            .....|.|.....||||:|:..|:|.||..|:::.|||:..|    |..:.|.:|:::...:..|
  Rat   306 TFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVYLYLQVSALLF 370

  Fly   374 EERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAG---NGSVFIYLGSENGLRDPPSQC 435
            ::..:.:...:.||||::::.:||:|:|||||:|:|.||||   .|.|.||.|:..||...|||.
  Rat   371 QDPQVLTGTETFGRFGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNARGLHSKPSQV 435

  Fly   436 LDAPSQQPSKYGSYM----FGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKIHA--II 494
            |.      ..:||..    ||..|...:|||.|.:.|..:||.....|.:|||.|||.:.|  ::
  Rat   436 LQ------GIWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGEGKVAVYRARPVVTVDAQLLL 494

  Fly   495 KPKLQNVNPEEERV----------NITVCYRLSSKSDSKAKALMEQELVIRID-IDTKSKIKLAV 548
            .|.:.|:..:..::          ::.||..::.:|.|...|||.:   :::| :..|..||..:
  Rat   495 HPMIINLENKTCQIPEFPTPVACFSLRVCASIAGQSISNTVALMAE---VQLDFLKQKGAIKRTL 556

  Fly   549 FDEEHGSQMSF-----KAKAFHEEICSEFQI----EMDKRAKFTPIALEMQYELSKKIPNSGDFC 604
            |...|.|.:.|     :.|:.|   |.:|.:    |.:.|.|.:||.:.:.|.|.......|  .
  Rat   557 FLHNHQSHLIFPFVMRQQKSLH---CQDFMVYLRDETEFRDKLSPINVSLNYSLDDSTFEDG--L 616

  Fly   605 EDCAVVDPAEPKFVTEYITFNTGCATD-VCVADLKISCINASSTLVLGTTAVLRLTYNITNNGEF 668
            |...:::......|||.......|..| :||.||::|.......:::|....|.|..|..|.||.
  Rat   617 EVKPILNHYRENVVTEQAHILVDCGEDNLCVPDLRLSARPDKQEIIIGDENHLMLIINARNEGEG 681

  Fly   669 AYHPKFSV------------TNSAGLSLAQVPGNCKVNEAVMVCDLNHGQRMAKGDTDSLTISFD 721
            ||..:..|            .|:.||.|.......:....::||||  |..|..|...||.:.|.
  Rat   682 AYEAELFVMIPEEADYVGIERNNKGLRLLSCEYKMENVTRMVVCDL--GNPMVTGTNFSLGLRFA 744

  Fly   722 VRQLRGRSLEIQAEV-LSARDESNPENNKLTNVLSLREKADIYVSGVQTNDHVVL-------KES 778
            |.:|...::.|..:: :.:.::.||::|.::..:::...|.:.:.||.....:||       .|.
  Rat   745 VPRLEKTNMSINFDLQIRSSNKDNPDSNFVSVQINVTAVAQVEIRGVSHPPQIVLPIHNWEPAEE 809

  Fly   779 PYTAE-----VVNYYEIKSHGPSTLENLTVSLYIPVAYKTPDSTNVKHIVTSSPKIQSKYAHKIM 838
            |:..|     |.:.||:.:.||||:.:..:.:..|.:.:......|.|:.|..| :|.:...:|.
  Rat   810 PHKEEEVGPLVEHIYELHNIGPSTISDSILEVGWPFSAREEFLLYVFHLQTLGP-LQCQTNPEIN 873

  Fly   839 PINFIDQNNALANNFAIDHDQSTLLFSATPQHENVGNLSGIVEQNPSISLL--NEDLPV------ 895
            |                    ..:..:|:|  |:...||..: :|.:|..|  ..|:||
  Rat   874 P--------------------QDIKPAASP--EDTPELSAFL-RNATIPHLVRKRDVPVVQPHRQ 915

  Fly   896 NNTLVLNCQDTNVTLCVPVEI---RLENGLQLKPEELMNMTVSFTVNLKDADDIWEYFVIQTDLK 957
            :...:|||  ||:. |:.:..   ||..|     |..:         ||....:|.:..:|
  Rat   916 SPAKILNC--TNID-CLQISCAVGRLGGG-----ESAV---------LKVRSRLWAHTFLQ---- 959

  Fly   958 VHKIGDP----TLSSFTIEK---------------KIESNVICKHAEIA----IWKIIVSVIVGI 999
              :..||    :|.||.::|               .|:::||.....::    :|.||:::::|:
  Rat   960 --RKNDPYALASLVSFEVKKIPYKEQPAKLPAGSTAIKTSVIWATPNVSFSIPLWVIILAILLGL 1022

  Fly  1000 LVFSAATYALYKRGFFKRA-----IKDDLKQLIRD 1029
            ||.:..|.||:|.|||.||     ...|.:||..|
  Rat  1023 LVLAILTLALWKCGFFDRARPPQDEMTDREQLTSD 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	25/76 (33%)
		Int_alpha	384..434	CDD:214549	26/52 (50%)
		Int_alpha	447..>492	CDD:214549	19/48 (40%)
		Integrin_alpha2	484..808	CDD:285619	90/371 (24%)
Itga8	NP_001167443.1	Int_alpha	53..111	CDD:214549	21/60 (35%)
		Int_alpha	316..>364	CDD:214549	17/47 (36%)
		Int_alpha	382..436	CDD:214549	28/53 (53%)
		Int_alpha	447..491	CDD:214549	17/43 (40%)
		Integrin_alpha2	482..933	CDD:285619	115/487 (24%)
		Integrin_alpha	1034..1048	CDD:278771	6/13 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335730
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740