Protein Alignment ItgaPS4 and if

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_523378.2
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Alignment Length: 1098
• Identity: 266/1098 - (24%)
• Similarity: 453/1098 - (41%)
• Gaps: 239/1098 - (21%)

  Fly     5 LVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRS--SYFGFSLVIRE-----------KSIMV 56
            |:::|:|:.:  :.|||        :.|.....|:|  |.||||:.:.:           .|::|
  Fly    20 LILLLIAMSA--HGYNI--------DLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVSLIV 74

  Fly    57 AAPRANSSLEAQRNISEPGVIFRCYFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGA 121
            .||:.::| ..|:.::|.|.:|:|.. :.::|.....|:|||.:.:..:   ....|.::|||..
  Fly    75 GAPKFDTS-RYQQGVTEAGGVFKCSL-NDDDCKLVPFDSKGNNRNVDKE---VVDRKSYQWLGAT 134

  Fly   122 MDGGTRDSDKFLVCAPR--FYSINNENDYN---NGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQV 181
            :..| ||||..:.||||  |:::.....:.   .|.|:    |..|.:  |..|..|.|
  Fly   135 VATG-RDSDLVVACAPRYVFHTMTPSRAFRIDPVGTCF----TSHNFE--EFYEVSPCR------ 186

  Fly   182 LKLADTNLIPYYSMG--ELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIK--------- 235
                 ||...|:..|  :.|.||.::.:.|:|.:||||...|:|..:  ...|..|
  Fly   187 -----TNNWGYHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQGQTY--SIPPDAKFPFKPPLYQ 244

  Fly   236 -TSSGRQRRGMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQF 299
             ..:|......:..|..|:.....::....:.||.||::.:|.||......|  ....|||.|..
  Fly   245 PFGTGGMASSHDVTRPENQVFSTSESASVNDDSYLGYSMVTGDFDGDRSEDV--AIGMPRGGNLV 307

  Fly   300 GE--------AYIFDIYEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYA---- 352
            |.        |.||:|           .|...|||||||:...|::|||..|::|.||:|.
  Fly   308 GRIVVNRWNMANIFNI-----------TGRQIGEYFGYSLATSDVDGDGLDDLLIGAPMYTDPDN 361

  Fly   353 LRNSYDDGAIYVFINKGSFTFEER----IIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPF- 412
            :...||.|.:|:.: :|..|.|:|    .||....|.||||..|:.:||:|.|||.|.|||||:
  Fly   362 VEGKYDVGRVYILL-QGGPTEEKRWTTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYD 425

  Fly   413 --AGNGSVFIYLGSENGLRDPPSQCLDAPSQQPSKYGSY--MFGHGLSRGSDIDGNGFNDFAIGA 473
              .|.|.|:|:.||..|....|||.:  .|:|..:...|  .||..||.|.|:|||.:.|.|:||
  Fly   426 GPEGRGVVYIFHGSPMGPLAKPSQII--KSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGA 488

  Fly   474 PNAEAVYLYRAYPVVKIHA----IIKPKLQNVNP-------EEERVN---ITVCYRLSSKSDSKA 524
            .:::.|:::::.||..::|    ....||.:::.       :.::|.   :|.|:..:.:
  Fly   489 YSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWSYTGR----- 548

  Fly   525 KALMEQELVIRID--IDTKSKIKLAVF---DEEHGSQMSFKAKAFHEEIC-SEFQIEMDK-RAKF 582
              .:.::|...:.  :|.|..:...:|   ||....:.......:.::.| :|....:|| :.|.
  Fly   549 --YLPEQLDFDVSWLLDAKKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKL 611

  Fly   583 TPIALEMQYELSKKIP------NSGDFCEDCAVVDPAEPKFVTEYITFNTGCATD-VCVADLKIS 640
            ||:.:|.:|.|....|      :.....|  .|:|......:.:.|.....|..| :|..|||:.
  Fly   612 TPLEVEARYNLRSSRPLDPMVRHRRSILE--PVIDQNREIVLRDAINIQKNCGPDNICEPDLKLK 674

  Fly   641 CINASSTLVLGTTAVLRLTYNITNNGEFAYHPKFSVTNSAGLSLAQV---------PGNCK---- 692
             ::.....:.|:...|.:...|:|..|.|:...|.:.....|...::         |..|.
  Fly   675 -VSTVDKYLFGSPEPLVIEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTP 738

  Fly   693 VNEAVMVCDLNHGQRMAKGDTDSLTISFDVRQLRGRSLEIQAEVLSARD---ESNPEN------- 747
            .|...:.||:  |..:..|......||....:..|.|        |:.|   |:|..|
  Fly   739 ENNHTLKCDI--GNPLESGKIAHFKISLVPEEKYGSS--------SSYDFYWEANSTNLEKPGSE 793

  Fly   748 --NKLTNVLSLREKADIYVSGVQTNDHVVLKESPYT------------AEVVNYYEIKSHGPSTL 798
              ||:...:.:....|:.:.|....|:.:.|...|.            .:||:.|||:::.||.:
  Fly   794 YDNKIRQSVGIWVDTDLDIKGTSLPDYQLYKADDYKELENATKEDDIGPQVVHIYEIRNNRPSII 858

  Fly   799 ENLTVSLYIPVAYKTPDSTNVKHIVT---SSPKIQ------SKY----AHKIMPINFIDQNNALA 850
            |...|.:::|  |:|.....:.:::.   :..|||      ::|    ..|::..:::....|:.
  Fly   859 EEAEVFIHLP--YETIVGDPLMYLLNQPETGGKIQCDDVAFNEYNLLLDEKLVKKSYLQAQGAIW 921

  Fly   851 NNFAIDHDQSTLLFSATPQHENVGNLSGIVEQNPSISLLNEDLPVNNTLVLNCQDTNVTLCVPVE 915
            |:..:....|:        ..:.|..|..:|:......      |...||.|..|.
  Fly   922 NSAQVSGQSSS--------SSSSGGASVHIEKARGEGF------VRGVLVSNSTDA--------- 963

  Fly   916 IRLENGLQLKPEELMNMTVSFTVN-LKDADDIWEYFVIQTDLKVHKIGDPTL--SSFT 970
                 |.:|.|:::.......|:. |.||.      .:..|.....:.:|.:  :|||
  Fly   964 -----GDKLSPKQVEQRRQEDTLEALGDAS------FVHRDRASQAVQEPQVNQTSFT 1010

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	32/80 (40%)
		Int_alpha	384..434	CDD:214549	26/52 (50%)
		Int_alpha	447..>492	CDD:214549	17/46 (37%)
		Integrin_alpha2	486..808	CDD:462478	75/386 (19%)
if	NP_523378.2	Int_alpha	46..110	CDD:214549	16/65 (25%)
		Int_alpha	275..>316	CDD:214549	13/42 (31%)
		Int_alpha	398..451	CDD:214549	27/52 (52%)
		Int_alpha	466..>497	CDD:214549	14/30 (47%)
		Integrin_alpha2	500..892	CDD:462478	80/413 (19%)
		Glutenin_hmw	<1121..1216	CDD:367362