Protein Alignment ItgaPS4 and Itga5

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001101588.1
• Gene: Itga5 / 315346
• RGDID: 2925
• Length: 1099
• Species: Rattus norvegicus
• Alignment Length: 1136
• Identity: 285/1136 - (25%)
• Similarity: 465/1136 - (40%)
• Gaps: 256/1136 - (22%)

  Fly     5 LVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLVIREK-----SIMVAAPRANSS 64
            |:::|.....::..:|:.....:||:.|.      .|.||||:.....     |::|.||:||:|
  Rat    80 LLLLLWPPPLQVGGFNLDAEAPAVLSGPP------GSLFGFSVEFYRPGRDGVSVLVGAPKANTS 138

  Fly    65 LEAQRNISEPGVIFRC-YFESGNNCSPYNIDTKGN-------YKGMPNDGLLTAKNKDFRWLGGA 121
               |..:.:.|.::.| :..|...||....|:||:       |...|      .:.|..:|.|..
  Rat   139 ---QPGVLQGGAVYVCPWGTSPIQCSTIQFDSKGSRILESSLYSEEP------VEYKSLQWFGAT 194

  Fly   122 MDGGTRDSDKFLVCAPRFYSINNENDYNN---GMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLK 183
            :   .......|.||| .||...|.|..|   |.||..::     :.|.::|..|.|.:......
  Rat   195 V---RAHGSSILACAP-LYSWRTEKDPQNDPVGTCYLSTE-----NFTRILEYAPCRSDFGSAAG 250

  Fly   184 LADTNLIPYYSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQR-----R 243
            ..       |..|  |.||..: ...::::|.||...|:|.: |......|..|...|.     :
  Rat   251 QG-------YCQG--GFSAEFT-KTGRVVLGGPGSYFWQGQI-LSATQEQISESYYPQYLINPVQ 304

  Fly   244 GMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIFDIY 308
            |....|:.:....:         ||.||:|:.|.|...:  |..:||..|:||..:|  |:..:.
  Rat   305 GQLQTRQASSVYDD---------SYLGYSVAVGEFSGDD--TEDFVAGVPKGNLTYG--YVTVLN 356

  Fly   309 EDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRNS----YDDGAIYVFINKG 369
            ...|:..:...|.....||||:|.|.|.||||..|:::.|||...|.:    .:.|.:|:::.
  Rat   357 GSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQ-- 419

  Fly   370 SFTFEERIIRSPA------GSGGRFGTTLSRIGDINKDGYNDVAVGAPFAG---NGSVFIYLGSE 425
               ..|.|..:|:      ...||||::|:.:||:::|||||||:||||.|   .|.|||:.|..
  Rat   420 ---HPEGIEPTPSLTLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGP 481

  Fly   426 NGLRDPPSQCLD---APSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPV 487
            .||...|||.|.   |....|..:||.:.|     |.|:||||:.|..:|:...:...:||..|:
  Rat   482 GGLNTKPSQVLQPLWAAGHTPDFFGSALRG-----GRDLDGNGYPDLIVGSFGVDKALVYRGRPI 541

  Fly   488 VKIHAIIKPKLQNVNPEEER----------VNITVCYRLSSKSDSKAKALMEQELVIRIDID-TK 541
            :...|.:.......||||..          :|::.|...|.|....:...   |:.:::|.. .|
  Rat   542 ISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGF---EVELQLDWQKQK 603

  Fly   542 SKIKLAVF--DEEHGSQMSFKAKAFHEEICSEFQI----EMDKRAKFTPIALEMQYELSKKIP-- 598
            ..::.|:|  .::.....:...:....|.|.|.:|    |.:.|.|.:||.:.:.:.|..|.|
  Rat   604 GGVRRALFLASKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMD 668

  Fly   599 ----------NSGDFCEDCA--VVDPAEPKFVTEYITFNTGCATD-VCVADLKISCINASSTLVL 650
                      .|....||.|  ::|                |..| :||.||:::.......:.|
  Rat   669 SHGLRPVLHYQSKSRIEDKAQILLD----------------CGEDNICVPDLQLAVYGEKKHVYL 717

  Fly   651 GTTAVLRLTYNITNNGE-FAYHPKFSVT---NSAGLSLAQVPGN-----C---KVNEA-VMVCDL 702
            |....|.||:...|.|| .||..:..||   .:....|.:.|||     |   .||:: .:||||
  Rat   718 GDKNALNLTFLAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDL 782

  Fly   703 NHGQRMAKGDTDSLTISFDVRQLRG--RSLEIQAEVLSARDESNPENNKLTNVLSLREKADIYVS 765
              |..|..|.:....:.|.|..|:.  ::::...::|| ::.:|.::|.::..||:..:|.:.::
  Rat   783 --GNPMKAGTSIWGGLRFTVPHLQDTKKTIQFDFQILS-KNLNNSQSNMVSFPLSVEAQAQVSLN 844

  Fly   766 GVQTNDHVVL------------KESPYTAEVVNYYEIKSHGPSTLENLTVSLYIPVAYKTPDSTN 818
            ||...:.|:.            ||......|.:.||:.:.|||::....:.:..|.|.:..
  Rat   845 GVSKPEAVIFPVSDWNPQDQPQKEGDLGPAVHHVYELINQGPSSISQGVLEISCPQALEGQ---- 905

  Fly   819 VKHIVTSSPKIQSKYAHKIMPINFIDQNNALANNFAIDHDQSTLLFSATPQHENVGNLSGIVEQN 883
                       |..|..|:..:     ||..:|              .||      |..|: |.:
  Rat   906 -----------QLLYVTKVTGL-----NNCTSN--------------YTP------NSQGL-ELD 933

  Fly   884 PSIS---LLNEDLP-----VNNTLVLNCQDTNVTLCVPVEIRLENGLQLKPEELMNMTVSFTVNL 940
            |.:|   |...:.|     .:.|.||.|.:..   |  ..:|.|.| .|..:|..::.:.|.|..
  Rat   934 PEVSPHHLQRREAPGRSSTTSGTQVLKCPEAK---C--FRLRCEFG-PLHRQESRSLQLHFRVWA 992

  Fly   941 K------------DADDIWE-----YFVIQTDLKVHKIGDPTLSSFTIEKKIESNVICKHAEIAI 988
            |            ..:.::|     |.::...|...|:...|...:|  |...||      .:.:
  Rat   993 KTFLQQEYQPFSLQCEALYEALKMPYQILPRQLPQKKLQVATAVQWT--KAEGSN------GVPL 1049

  Fly   989 WKIIVSVIVGILVFSAATYALYKRGFFKRAI 1019
            |.||::::.|:|:.....|.|||.|||||::
  Rat  1050 WIIILAILFGLLLLGLLIYVLYKLGFFKRSL 1080

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	28/82 (34%)
		Int_alpha	384..434	CDD:214549	27/52 (52%)
		Int_alpha	447..>492	CDD:214549	14/44 (32%)
		Integrin_alpha2	484..808	CDD:285619	85/382 (22%)
Itga5	NP_001101588.1	Int_alpha	108..166	CDD:214549	18/66 (27%)
		Int_alpha	317..>359	CDD:214549	15/54 (28%)
		Int_alpha	371..432	CDD:214549	21/65 (32%)
		Int_alpha	438..492	CDD:214549	29/53 (55%)
		Int_alpha	504..556	CDD:214549	15/56 (27%)
		Integrin_alpha2	539..971	CDD:285619	107/499 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335751
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840