Protein Alignment ItgaPS4 and Itga3

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001293091.1
• Gene: Itga3 / 16400
• MGIID: 96602
• Length: 1068
• Species: Mus musculus
• Alignment Length: 1109
• Identity: 256/1109 - (23%)
• Similarity: 433/1109 - (39%)
• Gaps: 269/1109 - (24%)

  Fly    41 SYFGFSLVIREKS-------IMVAAPRANSSLEAQRNISEPGVIFRCYFES-GNNCSPYNIDTKG 97
            |.||:|:.:..::       ::..|||..:..:...|  ..|.::.|...: .::|...:|..|.
Mouse    50 SLFGYSVALHRQTERQQRYLLLAGAPRDLAVGDDYTN--RTGAVYLCPLTAHKDDCERMDISEKS 112

  Fly    98 NYKGMPNDGLLTAKNKDFRWLGGAMDGGTRDSDKFLVCAPRF------------------YSINN 144
            :    |:..::     :..|||..: .....:.:.||||.|:                  |...|
Mouse   113 D----PDHHII-----EDMWLGVTV-ASQGPAGRVLVCAHRYTKVLWSGLEDQRRMVGKCYVRGN 167

  Fly   145 E---------NDYNNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIPYYSMGELGL 200
            :         ..|:|.||.         .:|:.::.                      .|.:||.
Mouse   168 DLQLDPGDDWQTYHNEMCN---------SNTDYLQT----------------------GMCQLGT 201

  Fly   201 SAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRGMNTNRKCNECNPEPKNFGQEE 265
            |...:.:.  :..||||...|||:.::            .||:..:.:......:.|..|.
Mouse   202 SGGFTQNT--VYFGAPGAYNWKGNSYM------------IQRKDWDLSEYSYRGSEEQGNL---- 248

  Fly   266 FSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIF------DIYEDSIYKYHEFRGNHFG 324
              |.||.|..|.........:..|..||| :...|..::.      |:....:.|     |...|
Mouse   249 --YIGYTVQVGNAILHPTDIITVVTGAPR-HQHMGAVFLLKQESGGDLQRKQVLK-----GTQVG 305

  Fly   325 EYFGYSVLAEDLNGDGKTDVIISAPLYALRNSYDDGAIYVFINKGSFTFEER---IIRSPAGSGG 386
            .|||.::...|||.||..|:::.||.|..|.....||:|||:|:...:|.::   ::..|:.|.
Mouse   306 AYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVFMNQAGASFPDQPSLLLHGPSRSA- 369

  Fly   387 RFGTTLSRIGDINKDGYNDVAVGAPFAGNGSVFIYLGSENGLRDPPSQCLDAPSQQPSKYGSYMF 451
             ||.:::.|||||:||:.|:||||||.|.|.|:||..|..||...|.|.:.  .::....|...|
Mouse   370 -FGISIASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSGGLLRQPQQIIH--GEKLGLPGLATF 431

  Fly   452 GHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKI-H-------AIIKPKL---------- 498
            |:.||...|:|.|.:.|..:|: .::.:.|.||.||:.| |       |::.|.|
Mouse   432 GYSLSGKMDVDENLYPDLLVGS-LSDHIVLLRARPVINILHRTLVARPAVLDPALCTATSCVQVE 495

  Fly   499 ------QNVNPEEERVNITVCYRLSSKSDSKAKALMEQELVIRIDIDTKSKIKLAVFDEEHGSQM 557
                  |:......|.|||:.|.|.:..|.:...|            ..::.:.:||   ||
Mouse   496 LCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL------------RFARSQSSVF---HG--- 542

  Fly   558 SFKAKAFHEEICSEFQ-IEMDK-RAKFTPIALEMQYELSKKIPNSGDF----CEDCAVVDPAEPK 616
            .|.....|   |...: :.||. |.|..||.:.|.|.|..::|:....    .:...|::.|:..
Mouse   543 FFSMPETH---CQTLELLLMDNVRDKLRPIVIAMNYSLPLRMPDRLKLGLRSLDAYPVLNQAQAM 604

  Fly   617 FVTEYITFNTGCATD-VCVADLKISCINASSTL-------VLGTTAVLRLTYNITNN------GE 667
            .....:.|...|..| .|.::|::.....|..|       ....|..|.|:.|:||:      ||
Mouse   605 ENHTEVHFQKECGPDNKCDSNLQMRAAFLSEQLQPLSRLQYSRDTKKLFLSINVTNSPSSQRAGE 669

  Fly   668 FAYHPKFSVTNSAGLSLAQV--PGNCKVNEAVMVCDLNH----GQRMAKGDTDSLTISFDV--RQ 724
            .|:....::...:.|.|:.|  .|.|:.|...::|:|.:    .|||      .|.|:|:|  ..
Mouse   670 DAHEALLTLEVPSALLLSSVRPSGTCQANNETILCELGNPFKRNQRM------ELLIAFEVIGVT 728

  Fly   725 LRGRSLEIQAEVLSARDESNPENNKLT---------NVLSLREKADIYVSGVQTNDHVVLKESPY 780
            |..|.|.:..::.::..:.|.:...||         ::..:..:...:..|.     |:.:.:..
Mouse   729 LHTRDLPVLLQLSTSSHQDNLQPVLLTLQVDYTLQASLSLMNHRLQSFFGGT-----VMGEAAMK 788

  Fly   781 TAEVVN---YYEIK----SHGPSTLENLTVSLYIPVAYKTPDSTNVKHIV-TSSPKIQSKYAHKI 837
            |||.|.   .||.:    ..|.:.|..|.:.|..|.     :.||.|.:: .:...|.|..:...
Mouse   789 TAEDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPY-----EVTNGKWLLYPTEITIHSNGSWPC 848

  Fly   838 MPINFIDQNNALAN--NFAIDHDQSTLLFSATPQHENVGNLSGIVEQNPSISLLNEDLPVNNTLV 900
            .|      :..|.|  |..:.....|.|   :||........|..:.:|.::|.......:.| |
Mouse   849 QP------SGNLVNPLNLTLSDPGVTPL---SPQRRRRQLDPGGDQSSPPVTLAAAKKAKSET-V 903

  Fly   901 LNCQDTNVTLCVPVEIRLENGLQLKPEELMNMTV-------SFTVNLKDAD----DIWEYFVIQT 954
            |.|.:.... ||.:|..|.:     ...:.|:||       :|..:.||.|    |.|....::|
Mouse   904 LTCSNGRAR-CVWLECPLPD-----TSNITNVTVKARVWNSTFIEDYKDFDRVRVDGWATLFLRT 962

  Fly   955 DLKVHKIGDPTLSS------FTIEKKIESNVICK-HAEIAIWKIIVSVIVGILVFSAATYALYKR 1012
            .:       ||::.      |:::  |:|.::.: .|||.:|.::|:|..|:|:.......|:|.
Mouse   963 SI-------PTINMENKTTWFSVD--IDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKC 1018

  Fly  1013 GFFK 1016
            .|||
Mouse  1019 DFFK 1022

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	29/75 (39%)
		Int_alpha	384..434	CDD:214549	26/49 (53%)
		Int_alpha	447..>492	CDD:214549	17/52 (33%)
		Integrin_alpha2	486..808	CDD:462478	84/389 (22%)
Itga3	NP_001293091.1	FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	38..103		10/54 (19%)
		Int_alpha	48..108	CDD:214549	11/59 (19%)
		FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	110..171		12/70 (17%)
		FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	185..235		15/94 (16%)
		FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	236..293		12/63 (19%)
		FG-GAP 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	294..355		22/65 (34%)
		Int_alpha	305..353	CDD:214549	20/47 (43%)
		FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	357..412		26/56 (46%)
		Int_alpha	368..418	CDD:214549	27/51 (53%)
		FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	416..478		18/64 (28%)
		Integrin_alpha2	464..918	CDD:462478	107/501 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	865..890		6/27 (22%)