Protein Alignment ItgaPS4 and LOC1274451

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_313576.5
• Gene: LOC1274451 / 1274451
• VectorBaseID: AGAMI1_007450
• Length: 1145
• Species: Anopheles gambiae
• Alignment Length: 1177
• Identity: 388/1177 - (32%)
• Similarity: 612/1177 - (51%)
• Gaps: 171/1177 - (14%)

  Fly     4 LLVIVLLALQSEINAYNISPYPNSVLNFPELE---GNRRSSYFGFSLVIREKSIMVAAPRANSSL 65
            :|:::||.|..:.:.:|:||.||.|...|.|:   ...||||||:||.:|...::|.||||.|.|
Mosquito    17 MLLLLLLLLAGDGDTFNLSPVPNYVFREPNLQLHMEKGRSSYFGYSLNLRPGGVIVGAPRAQSDL 81

  Fly    66 EAQRNISEPGVIFRCYFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGGTRDSD 130
            ..||.::|.|.|:||:|..| .|:||..|..||.|...:|....::.|||:.||.||||...|.|
Mosquito    82 ATQRKVNETGAIYRCHFTDG-ECAPYYFDKAGNTKAEQSDFAYNSEKKDFQMLGAAMDGHGSDGD 145

  Fly   131 KFLVCAPRFYSINNENDYN--NGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIPY- 192
            :|:||||:  :|:...||.  :|:||....|.:..:..|:.:..|||.:.||:.|.|      |
Mosquito   146 RFVVCAPK--TISELVDYYLLHGICYVTDGTEQEQEPKEIRKIIPLRAKDKQLHKDA------YG 202

  Fly   193 ----YSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRG------MNT 247
                |..||.|:|.||:||..::|:||||:..|:|:|...:.  .:..:.|..||.      ..|
Mosquito   203 QYYNYMYGEQGISVHVTDDGEEILIGAPGVFNWRGTVVRYRR--RVSDAGGLSRRDDWSAQHRPT 265

  Fly   248 NRKCNEC------NPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIFD 306
            ||...:.      .|.|.....::.|||||||.||.|...  ..:||||:||:.:.|.|:.:|||
Mosquito   266 NRHKRQIIQYVSDVPNPYFSAVQDDSYFGYAVGSGDFRGD--KKILYVASAPQSSGQVGDVFIFD 328

  Fly   307 I------YEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRNSYDDGAIYVF 365
            |      .|..|..::.|.|...||||||::||||.||||..|:.|:||:::....:|:|.:||:
Mosquito   329 IINADSFLETQIKVHYTFPGQQQGEYFGYALLAEDFNGDGFADLAIAAPMHSRFGDHDNGVVYVY 393

  Fly   366 INKGSFTFEERIIRSPAGS---GGRFGTTLSRIGDINKDGYNDVAVGAPFAGNGSVFIYLGSENG 427
            .|:|...|:  :....:||   .|||||:|::|||||.|||||:||||||.|||:|:|:|||.:|
Mosquito   394 WNEGELNFQ--LQGKLSGSQEVAGRFGTSLAKIGDINMDGYNDIAVGAPFEGNGAVYIFLGSVDG 456

  Fly   428 LRDPPSQCLDAP-----SQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPV 487
            |:..|||.|.||     |.||      |||..||||||||.||:||.|:|:||.|.||:||.|||
Mosquito   457 LQSKPSQRLTAPANELLSPQP------MFGFALSRGSDIDANGYNDLAVGSPNDEKVYVYRTYPV 515

  Fly   488 VKIHAIIKPKLQNVNPEEERVNITVCYRLSSKSDSKAKALMEQELVIRIDIDTKSKIKLAVFDEE 552
            |||...:....:.:..|:...::::|......:..:....:..||.:      .:::........
Mosquito   516 VKIDVDVTSSKRELTLEDTTFDLSICMNAIFATGQQFDVQLNYELSV------DAQVGRVTLPGV 574

  Fly   553 HGSQMSFKAKAFHEEICSEFQIEMDKRAK--FTPIALEMQYELSKKIPNSGD--FCEDCAVVDPA 613
            .|::.:..........|....:.:...|.  :.|:.:|:.|||.:::|...|  ||.:||::||.
Mosquito   575 GGNKRNETITVTGTNECRRIDVRLKATAASIYKPVLVELSYELVRQLPADTDAGFCAECALLDPT 639

  Fly   614 EPKFVTEYITFNTGCATDVCVADLKISC--INASSTLVLGTTAVLRLTYNITNNGEFAYHPKFSV 676
            .|..:.:.|:|.|||..:|||:||::|.  ::.|...|||::....:.:.:.|.||.||.|:.:|
Mosquito   640 VPNRLIQKISFKTGCQGEVCVSDLRLSARWLDISPVYVLGSSKKATIEFEVYNAGENAYLPQLNV 704

  Fly   677 T-NSAGLSLAQVPGNCK----VNEAVMVCDLNHGQRMAKGDTDSLTISFDVRQLRGRSLEIQAEV 736
            | ..|.|:||::...|:    |....::||||:|..:....|...|:..|:.:|.|.|.||:||.
Mosquito   705 TLTPARLTLAKLTSECQQTITVEGVNVLCDLNNGLPLRSSHTSRYTLILDMTKLEGSSAEIRAEA 769

  Fly   737 LSARDESNPENNKLTNVLSLREKADIYVSGVQTNDHVVLKESPYTAEVVNYYEIKSHGPSTLENL 801
            ||:.:||..|:|.|..||:|:|.:||.:.|..:...|.|::......:....::.|:||||...|
Mosquito   770 LSSSEESAQEDNFLEQVLTLQEFSDIEIIGKTSTSEVFLEQQSGLLNITYEIQVHSNGPSTFRRL 834

  Fly   802 TVSLYIPVAYKTPDSTNVKHIVT-SSPKIQSKYAHKIM-----------------------PINF 842
            ..:|.:|:.|..|.:.....|:. ::..:...|::|.:                       |:..
Mosquito   835 GFTLDVPLVYHKPSAGRSFQIINLNNIAVTGYYSYKTLDYTWTQNETILLPNPIEQDHILPPVVD 899

  Fly   843 IDQNNALANNFAI------------------DHDQSTLLFSATPQHENVGNLSGIVEQ------- 882
            :::.:.|.::|.:                  .:|.|::     ..|....||.|..|.
Mosquito   900 VEELHRLPSDFDLLSGGGGGMVGYPGENQPHGYDPSSV-----GMHRRRRNLDGAPESTYNRYTG 959

  Fly   883 --------NPSISLLNE----DLPVNNTLVLNC-QDTNVTLCVPVEIRLENGLQLKPEELMNMTV 934
                    ..|:|.:||    .||.|.||..|| ::.::..|..:.:.::   ..:|   .|:.:
Mosquito   960 QLTSHSRTRRSLSKVNEAIVQALPGNRTLFFNCAEEDSLIECARLNVAVD---IFRP---TNVPI 1018

  Fly   935 SFTVNLK-DADDIWEYFVIQTDL-------KVHKIGDPTLSSFTIEKKIESN---VICKHAE--I 986
            ..|::.: |.|.|.|.|:.:.|:       .|||.|||...:|   :::.||   |:.::::  .
Mosquito  1019 VITLHFQLDLDAIGEAFLEREDIFALTMLADVHKEGDPDGVTF---RQVRSNPFTVVYRYSDGST 1080

  Fly   987 AIWKIIVSVIVGILVFSAATYALYKRGFFKRAIKDDLKQLIRDSFEDGIIRTEMEENAQ-SQGDA 1050
            .||..|||.:.|:|:..|.:|.||:.||||||.|:::::|.|:|       |.:.|..| :|..|
Mosquito  1081 PIWVYIVSALGGLLLLVAISYGLYRAGFFKRATKEEMEKLHRES-------TRLNEPEQVNQSPA 1138

  Fly  1051 DLDEKLD 1057
            ::..:|:
Mosquito  1139 EVSTELN 1145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	34/75 (45%)
		Int_alpha	384..434	CDD:214549	34/52 (65%)
		Int_alpha	447..>492	CDD:214549	30/44 (68%)
		Integrin_alpha2	486..808	CDD:462478	93/332 (28%)
LOC1274451	XP_313576.5	None