Protein Alignment ItgaPS4 and if

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_061518066.1
• Gene: if / 1272247
• VectorBaseID: AGAMI1_012318
• Length: 1538
• Species: Anopheles gambiae
• Alignment Length: 994
• Identity: 260/994 - (26%)
• Similarity: 415/994 - (41%)
• Gaps: 179/994 - (18%)

  Fly     7 IVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLVI-REKS---IMVAAPRANSSLEA 67
            ::|:.|.....|:|:     ..:||...||: .||.||||:.: ||::   ::|.||.||:|
Mosquito    30 LLLVWLGQTATAFNL-----DTINFILKEGD-PSSMFGFSVALHREQNNSWVIVGAPTANTS--- 85

  Fly    68 QRNISEPGVIFRCYFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGGTRDSDKF 132
            |..:.:.|.::||.......|.....|||||.....|:.:.|..|   :|.|..:.....|. ..
Mosquito    86 QPGVIKGGAVYRCDIYDDYRCYLLPFDTKGNTYNDQNEQIDTKSN---QWFGATVASAGIDG-PL 146

  Fly   133 LVCAPR--FYSI---NNENDYNNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIPY 192
            :.||||  |:.:   ..|.....|.||...:..:|.:...     |.|           |....|
Mosquito   147 VACAPRYVFHQLQPRKAERVEPVGTCYLAKNNMQNFEDIS-----PCR-----------TAYWGY 195

  Fly   193 YSMG--ELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKT--------------SSGRQ 241
            :..|  :.|.||.:::|.|:|.:||||...|:|.::      ||.|              ..|.|
Mosquito   196 HRQGSCQAGFSAAITNDGSRLFIGAPGSYYWQGQMY------SINTDVVFPYKPPRYGHFGEGGQ 254

  Fly   242 RRGMNTNRKCNECNPEPKNF------GQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFG 300
            ....:.|      ||:.|.:      .:|:.||.||:.::|.|:......|  ....|||....|
Mosquito   255 IYSFSLN------NPKDKVYKTLEDTKKEDDSYLGYSSTTGDFNGDGTQGV--AVGKPRGARLLG 311

  Fly   301 EAYIFDIYEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRNS---YDDGAI 362
            :..   ||..::.......|...|.|||||:.|.|::||...|:||.||:|...|:   |:.|.:
Mosquito   312 KVL---IYSWNMTNQQNITGEQIGAYFGYSLAAVDVDGDKLDDLIIGAPMYTEPNNEGKYETGRV 373

  Fly   363 YVFINKGSF--TFEERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPF---AGNGSVFIYL 422
            |:.....:.  .|.|...|....|..|||..:..:.|:|.|||.|.|||||:   .|.|:|:|:.
Mosquito   374 YIMYQGAAADGRFRELDTRDGVNSKARFGLAVCSLADLNLDGYGDFAVGAPYDGPNGRGAVYIFY 438

  Fly   423 GSENGLRDPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPV 487
            ||..|.....||.:.|.........| .||..||.|.|:|||.:.|..:||..::...:::|.||
Mosquito   439 GSRTGPLAKASQVIQAEDMAGVTRLS-TFGFSLSGGIDLDGNQYPDMVVGAYESDKALVFKARPV 502

  Fly   488 VKIHA--IIKPK-----LQNVNPEEERVNITV-CYRLSS---KSDSKAKALMEQELVIRIDIDTK 541
            ..:.|  :.:||     |...|...:|.|.|| |..::|   .:......:::.|:...:|....
Mosquito   503 AAMVASTLFEPKSKLIALDVKNCALKRTNKTVPCTVVNSCLKYNGINVPPMLDIEISWTLDARKA 567

  Fly   542 SKIKLAVFDEEHG---SQMSFKAKAFHEEICSEFQIEMDKRAKFTPIALEMQYELSKKI------ 597
            ...::...|.|..   :|:...|:...|.|..:..:..:.|.|.||:.:||.|.|.:.:
Mosquito   568 RNPRMFFLDHEGNHTRTQLMRLARGKLECIEDKVYVADNIRDKITPLEVEMAYGLRQNVLGRQRR 632

  Fly   598 PNSGDFCEDCAVVDPAEPKFVTEYITFNTGCATD-VCVADLKISCINASSTLVLGTTAVLRLTYN 661
            |.:    ....|:|........:.|.....|..| |||.||::. :.:....:||:..:|.:...
Mosquito   633 PRA----HTEPVLDQNRGTVQRDAINIQKNCGPDNVCVPDLRME-VKSVDDYLLGSNNLLSVEVL 692

  Fly   662 ITNNGEFAYHPKFSVTNSAGL---------SLAQVPGNCKVNEA----VMVCDLNHGQRMAKGDT 713
            |||.||.|:...|.:....||         .:..||..|....|    .:.||:  |..::.|..
Mosquito   693 ITNRGEDAFEAGFYMAVPNGLDFRRVDRLGEVKDVPVLCTAPSAATNKTLKCDI--GNPLSSGKV 755

  Fly   714 DSLTI----SFDVRQLRGRSLEIQAEVLSARDE--SNPENNKLTNVLSLREKADIYVSGVQTNDH 772
            ....:    ||....  |.|.:...|..|...|  .|.::|.:...:.:..:.|:.:|||...|.
Mosquito   756 VHFKVILAPSFSAGM--GSSYDFYLETNSTNAELDGNRQDNVMRKTIGILVQTDLAMSGVSLPDQ 818

  Fly   773 VVLKESPYTA------------EVVNYYEIKSHGPSTLENLTVSLYIPVAYKTPDSTNVKHIVTS 825
            .....|.|.:            :||:.|||::.||||::.  ...::...|:|.|...:.::: :
Mosquito   819 FHYNHSEYKSLAEAKTERDIGPQVVHIYEIRNEGPSTIDE--AEFFVLWPYETVDGVPLMYLL-N 880

  Fly   826 SPK-------IQSKYAHKIMPINF-IDQNNALANNFAID--------HDQS---TLLFSATPQHE 871
            .|:       :.::||:   |:|. ||  :|||....:|        :..|   |..|::.....
Mosquito   881 QPETHGNIECLPTEYAN---PLNLAID--SALARKSFLDKVGVSSASYSSSMGRTAKFNSAAGSG 940

  Fly   872 NVGNLSGIVEQNPSISLLN 890
            .||     .|...|||.|:
Mosquito   941 TVG-----AEGASSISFLS 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	26/77 (34%)
		Int_alpha	384..434	CDD:214549	22/52 (42%)
		Int_alpha	447..>492	CDD:214549	16/44 (36%)
		Integrin_alpha2	486..808	CDD:462478	85/373 (23%)
if	XP_061518066.1	None