Protein Alignment ItgaPS4 and Itga9

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_598482.2
• Gene: Itga9 / 104099
• MGIID: 104756
• Length: 1036
• Species: Mus musculus
• Alignment Length: 1138
• Identity: 283/1138 - (24%)
• Similarity: 487/1138 - (42%)
• Gaps: 234/1138 - (20%)

  Fly     5 LVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLV----IREKSIMVAAPRANSSL 65
            |::.|:|......|||:.  ....:.|....|    |:||::::    ...:.::|.||:|:|..
Mouse    17 LLLALVAAGVPAGAYNLD--AQRPVRFQGPSG----SFFGYAVLEHFHDNTRWVLVGAPKADSKY 75

  Fly    66 EAQRNISEPGVIFRC--YFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMDGGTRD 128
            ..  ::..||.:|:|  :......|:..:: .:|..:|.| .|.....::|..|:|.::....|.
Mouse    76 ST--SVKSPGAVFKCRVHTNPDRRCTELDM-ARGRTRGAP-CGKTCRGDRDDEWMGVSLARQPRA 136

  Fly   129 SDKFLVCAPRFYSINNENDY--NNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIP 191
            ..:.|.||.|:.:|..|.|:  .:|.||.:   |.|:.:            |.:|       |||
Mouse   137 DGRVLACAHRWKNIYYEADHILPHGFCYLI---PSNLQA------------KGKV-------LIP 179

  Fly   192 YY-----SMGE------LGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRGM 245
            .|     ..||      .|::...:::  .::|||||...|.|::.:.....
Mouse   180 CYEEYKKKYGEEHGSCQAGIAGFFTEE--LVVMGAPGSFYWAGTLKVLNLTD------------- 229

  Fly   246 NTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEAYIF--DIY 308
            ||..|.|:     :......::|.||||::|:|...:::.|  |..||: :...|:.|||  |..
Mouse   230 NTYFKLND-----EAIMNRRYTYLGYAVTAGHFSHPSITDV--VGGAPQ-DEGIGKVYIFRADRR 286

  Fly   309 EDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYA-LRNSYDDGAIYVFINKGSFT 372
            ..::.|..:..|...|.|||.|:.|.|||.||.:|:::.||::: :|   |:|.:.|::|:|...
Mouse   287 SGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVGAPMFSEIR---DEGQVTVYLNQGHGA 348

  Fly   373 FEERI-IRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAP----FAGNGSVFIYLGSENGLRDPP 432
            .||:: :...|.....||.:::.:|||:.||:.|||||||    ||  |:|:||.|..||:....
Mouse   349 LEEQLTLTGDAAYNAHFGESIANLGDIDDDGFPDVAVGAPKEEDFA--GAVYIYHGDANGIVPKY 411

  Fly   433 SQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKIHA----- 492
            |..|......|:   ..|||..:|.|.|:||||:.|..|||..:::|.|.||.||:.:..
Mouse   412 SMKLSGRRLNPT---LRMFGQSISGGIDMDGNGYPDVTIGAFLSDSVVLLRARPVITVDVSIFLP 473

  Fly   493 ----IIKPKLQNVNPEEERVNITVCYRLSSKSDSKAKALMEQELVIRIDIDTKSK-----IKLAV 548
                |..|:..:.......:|:|||:|...|:......|   ...:..|:..|.|     :...:
Mouse   474 GSINITAPQCHDGQQPVNCLNVTVCFRFHGKNVPGEIGL---NYNLTADVAQKEKGQLPRVYFVL 535

  Fly   549 FDEEHGSQMSFKAKAFH-EEICSEFQIEMDKRAK--FTPIALEMQYELSKKIPNSGDFCEDCAVV 610
            |.|..| |:|.:.:..| :|:|..:...:.:|.:  .:||..|..|.|.:.:...    ||..:.
Mouse   536 FGETAG-QVSERLQLSHMDEVCHHYVAHVKRRVQDVISPIVFEAAYSLDEHVMGE----EDRELP 595

  Fly   611 DPAEPKFVTEYI--------------TFNTGCATDVCVADLKI-------SCINASSTLVLGTTA 654
            |      :|..:              .|...|.::.|.|||::       |....:..|.||...
Mouse   596 D------LTPVLRWKKGQRISQKNQTVFERNCQSEDCAADLQLRGKLLLSSVDEKTPHLALGAVK 654

  Fly   655 VLRLTYNITNNGEFAYHPKFSVTNSAGL------SLAQVPGNCKVNEA-VMVCDLNHGQRMAKGD 712
            .:.|..:|:|.|:.||....|...|..|      ...::..:|::.|: .:.|.:......:|..
Mouse   655 NISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSK 719

  Fly   713 TDSLTISFDVRQLRGRSLEIQAEVLSARDESNPE------NNKLTNVLSLREKADIYVSGVQTND 771
            .: .::.||...|.|.. ||.:.:::|: ..|.|      :|.||..:.|..:.|..::|:.:..
Mouse   720 YE-FSVIFDTSHLSGEE-EILSFIVTAQ-SGNLERSEALHDNTLTLTVPLVHEVDTSITGIVSPT 781

  Fly   772 HVVLKESPYTAEVVNYYEIKSH-------------GPSTLENLTVSLYIPVAYKTP---DSTNVK 820
            ..|..||...:..:...:.:.|             |||||...:||:..| :..:|   :...|:
Mouse   782 SFVYGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFP-SRLSPGGAEMFQVQ 845

  Fly   821 HIVTSSPK----IQSKYAHKIMPINFIDQNNALANNFAIDHDQSTLLFSATPQHENVGNLSGIVE 881
            .:|.|..|    :|......|:|   .:|.|.....||        .||.:.:
Mouse   846 DMVVSQEKGNCSLQRNPTPCIIP---QEQENIFHTIFA--------FFSKSGR------------ 887

  Fly   882 QNPSISLLNEDLPVNNTLVLNCQDTNVTLCVPVEIRLENGLQLKPEELMNMTVSFTVNLKDADDI 946
                 .:|:.:.|.:..|.|:|   |::.....|.|..|...|...|::.         ||:..:
Mouse   888 -----KVLDCEKPGSFCLTLHC---NLSALPKEESRTINLYMLLNTEILK---------KDSSSV 935

  Fly   947 WEYFV-----IQTDLKVHKI--GDP--TLSSFTIEKKIESNVICKHAEIAIWKIIVSVIVGILVF 1002
            .::..     ::..|:|.:|  |:|  ||..|.....:|     ....:..|.|.:|::||||:|
Mouse   936 IQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLE-----PRGYVVGWIIAISLLVGILIF 995

  Fly  1003 SAATYALYKRGFFKRAIKDDLK-QLIRDSFEDG 1034
            ......|:|.|||:|..|:.:: :..|...|||
Mouse   996 LLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDG 1028

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	26/74 (35%)
		Int_alpha	384..434	CDD:214549	23/53 (43%)
		Int_alpha	447..>492	CDD:214549	20/44 (45%)
		Integrin_alpha2	486..808	CDD:462478	81/385 (21%)
Itga9	NP_598482.2	FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	36..97		14/66 (21%)
		Int_alpha	45..102	CDD:214549	14/62 (23%)
		FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	109..175		20/81 (25%)
		FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	183..233		12/64 (19%)
		FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	234..290		18/63 (29%)
		Int_alpha	245..295	CDD:214549	17/52 (33%)
		FG-GAP 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	291..350		22/61 (36%)
		Int_alpha	301..348	CDD:214549	20/49 (41%)
		FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	352..409		24/58 (41%)
		Int_alpha	362..415	CDD:214549	24/54 (44%)
		FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	412..475		23/65 (35%)
		Int_alpha	426..>467	CDD:214549	20/40 (50%)
		Integrin_alpha2	461..904	CDD:462478	100/488 (20%)
		GFFKR motif. /evidence=ECO:0000250|UniProtKB:Q13797	1006..1010		3/3 (100%)