Protein Alignment ItgaPS4 and itga6

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_002934665.3
• Gene: itga6 / 100497992
• XenbaseID: XB-GENE-489982
• Length: 1095
• Species: Xenopus tropicalis
• Alignment Length: 1158
• Identity: 260/1158 - (22%)
• Similarity: 458/1158 - (39%)
• Gaps: 257/1158 - (22%)

  Fly     3 CLLVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLV-------IREKSIMVAAPR 60
            |...|....|.:| |..:.|..|.|:              ||||:.       :..:.::|.:||
 Frog    15 CCAFIAAFNLDTE-NVISKSGDPGSL--------------FGFSMAMHWQLDPVNRRLLLVGSPR 64

  Fly    61 ANSSLEAQR-NISEPGVIFRCYFESGN-NCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMD 123
            | .:|.||: |::  |.::.|...|.: :|:....|...:         ||:::|:.:|:|.::.
 Frog    65 A-KALPAQKANVT--GGLYVCDITSPSPSCNRVLFDDSVD---------LTSESKENQWMGVSVQ 117

  Fly   124 ----GGTRDSDKFLVCAPRF-----YSINNENDYNNGMCYWLSDTPKNIDSTEVMEKWPLRIEKK 179
                ||     |.:.||.|:     .:.|.||....|.||..|   :::..|:.|:.
 Frog   118 SQGPGG-----KIVTCAHRYERRTSVNTNYENRDITGRCYVFS---QDLTMTDEMDG-------- 166

  Fly   180 QVLKLADTNLIPYYSMG-------ELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKT- 236
                 .|.|.......|       :.|::|..:.|...::.||||...|||.|..:|:..:::.
 Frog   167 -----GDWNFCEGRRRGHEQFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGVVRAEQKNNTLEDL 226

  Fly   237 ---SSGRQRRGMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQ 298
               ..|....| ..|::.::..|.|.|      ||.|:::.:|...:|. ..:.:|:.|||.|:.
 Frog   227 FIFEDGPYETG-GENKRDSDLVPAPDN------SYLGFSLDTGRGITSK-EEMTFVSGAPRANHS 283

  Fly   299 FGEAYI--FDIYEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRNSYD-DG 360
            .....:  |...|..:...|.|:|......|||.|...|||.||..|:::.||.|..:|..: .|
 Frog   284 GAVVLLQKFPPNERMLSAVHTFQGEGLASSFGYDVAVVDLNRDGWKDIVVGAPQYFDKNDREIGG 348

  Fly   361 AIYVFINKGSFTFEERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPF-AGNGSVFIYLGS 424
            ||||:||:.....:...:|........||.::..|||||:|||.|:|||||: .|.|.|::|.||
 Frog   349 AIYVYINQQGNWNDVMPVRIVGTKDSMFGISVKNIGDINQDGYPDIAVGAPYDDGFGKVYVYHGS 413

  Fly   425 ENGLRDPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVK 489
            ::|:...|:|.::..|.     .:..||:.::...|:|.|.:.|.|:|: .:::|.::|:.||:.
 Frog   414 KDGIISEPAQVIEGRST-----NTRFFGYSIAGDMDLDQNSYPDIAVGS-LSDSVKVFRSRPVIT 472

  Fly   490 IHAIIKPKLQNV-------------------------NPEEERVNITVCYRLSSKSDSKAKALME 529
            |...||.....:                         ||:.....:|:......::|   :.|::
 Frog   473 IKKTIKVTPDRIDFNKKNCDAPSGICLEVEGCFEYTANPKTYNPVLTLSCTFELEND---RRLLQ 534

  Fly   530 QELVIRI-DIDTKSKIKLAVFDEEHGSQMSFKAKAFHEEICSEFQIEMDKRAKFTPIALEMQYEL 593
            :.|.:.. |:..:||:...:  |..|...       ...:.:..|:....|.|..|||:.:..|:
 Frog   535 KPLRMNFKDLPQESKLPKTI--ELRGQNQ-------RRCVTTTLQLLESIRDKLHPIAVSVSAEI 590

  Fly   594 S---KKIPNSGDFCEDCAVVDPAEPKFVTEYITF-NTGCATD-VCVADLKISC------------ 641
            .   ::...|....|...:::..|||..|..:.| ..||..| :|.:::::..
 Frog   591 KSVRRRKRQSSPLPELMPILNSNEPKNATANVQFLKEGCGEDNICNSNMQLKYKFLTREGSHDSF 655

  Fly   642 -----INASSTLVLGTTAVLRLTYNITNNGEFAYHPKFSVTNSAGLSL-AQVPGNCKV------- 693
                 .|....|.|.....:.|...:||......:||....::....| |::|.:...
 Frog   656 TELKQENGIPVLALKNQKEIALEVTVTNKPSNPANPKLDGDDAHEAQLTAELPSSLSYSKYVELN 720

  Fly   694 -------------NEAVMVCDLNHGQRMAKGDTDSLTISFDVRQLRGRSLEIQAEVLSARDESN- 744
                         |.:|:.|:|.:..:.....|..|.:|.:...:....|:|...:.:...::|
 Frog   721 PQLDKPLICASNPNGSVVFCELGNPFKRNANVTFYLILSTNEISVDTNELDIGLNLKTTSSQANL 785

  Fly   745 -PENNKLTNVLSLREKADIYVSGVQTNDHV-----VLKESPYTAE------------VVNY-YEI 790
             |...|...|:.|.    :.||||.....|     ||.||...:|            |.|: ..:
 Frog   786 APVAAKARVVVELL----LSVSGVAKPSQVYFGGNVLGESAMKSEDDIGNLIDFDFRVTNFGRPL 846

  Fly   791 KSHG--------PSTLENLTVSLYIPVAYKTPDSTNVKHIVTSSPKIQSKYAHKIMPINFIDQNN 847
            |:.|        |..:.|....||:           ||.......|::.:.|.:|..:..::...
 Frog   847 KALGTTFLNIQWPKEIYNGKWLLYL-----------VKMESEGLDKMECQPAGEINKLKLLESGK 900

  Fly   848 ALANNFAIDHDQSTLLFSATPQHENVG-NLSGIVEQNPSISLLNEDLPVNNTLVLNCQDTNVTLC 911
                               |.....:| :.||..::  |.||.:|    ...:.|:|  .|...|
 Frog   901 -------------------TRHRREIGESQSGTSDK--SFSLFSE----RKYMTLDC--NNQAKC 938

  Fly   912 VPVEIRL----ENGLQLKPEELMNMTVSFTVNLKDADDIWEYFVIQTDLKVHKIGDPTLSSFTIE 972
            |.::..|    .|.:......|.|.|.....:..:..||.....|..|.....|   .|::...:
 Frog   939 VTIKCPLHGMDSNAIIKARSRLWNSTFLEEYSKMNYLDILVKVFISVDTAAQNI---KLANEGYQ 1000

  Fly   973 KKI---ESNVICKHAEIAIWKIIVSVIVGILVFSAATYALYKRGFFKRAIKDD 1022
            .::   ....:.:::.:..|.|.|:::.|||:.:...:.|:|.|||||:..||
 Frog  1001 VRVTVFPEKTVAQYSGVPWWIIFVAILAGILMLALLVFLLWKCGFFKRSRYDD 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	29/73 (40%)
		Int_alpha	384..434	CDD:214549	24/50 (48%)
		Int_alpha	447..>492	CDD:214549	13/44 (30%)
		Integrin_alpha2	484..808	CDD:285619	77/420 (18%)
itga6	XP_002934665.3	Int_alpha	36..97	CDD:214549	18/77 (23%)
		Int_alpha	251..300	CDD:214549	13/55 (24%)
		Int_alpha	312..361	CDD:214549	21/48 (44%)
		Int_alpha	373..425	CDD:214549	25/51 (49%)
		Int_alpha	434..>457	CDD:214549	7/22 (32%)
		Integrin_alpha2	467..943	CDD:369878	95/529 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910