Protein Alignment ItgaPS4 and itga3

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_004918665.2
• Gene: itga3 / 100494331
• XenbaseID: XB-GENE-493979
• Length: 1030
• Species: Xenopus tropicalis
• Alignment Length: 1149
• Identity: 274/1149 - (23%)
• Similarity: 468/1149 - (40%)
• Gaps: 290/1149 - (25%)

  Fly     4 LLVIVLLALQSEINAYNISPYPNSVLNFPEL-EGNRRSSYFGFSLVIREKS-------IMVAAPR 60
            ||::.||...:  .|:|:.      ..||.| |.......||||:.:..:|       ::..||:
 Frog     9 LLLLALLCRPA--CAFNLD------TRFPVLKEAGVPGGLFGFSVSLHRQSEGEQRYLLLSGAPQ 65

  Fly    61 --ANSSLEAQRNISEPGVIFRCYFESG-NNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAM 122
              |..|::|.|.    |.::.|...|. |:|....||.:.:    |.:.::     :..|||..:
 Frog    66 DAAAPSVKANRT----GALYACPITSSTNDCFRVPIDPESD----PQNNII-----ENMWLGVTV 117

  Fly   123 DGGTRDSDKFLVCAPRFYSIN-----------------------NEND----YNNGMCYWLSDTP 160
            .....|. :.|||..|:.|:.                       ||:|    |:|.:|    |..
 Frog   118 ASQGPDG-RVLVCGHRYTSVRWSGEEDQRRMIGKCYIRGNNLELNEDDDWQTYHNELC----DPN 177

  Fly   161 KNIDSTEVMEKWPLRIEKKQVLKLADTNLIPYYSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSV 225
            .:.|:|                           .|.::|:|...:  ::.:..||||...|:||.
 Frog   178 SDFDAT---------------------------GMCQMGISGGFT--SNMVYFGAPGAYTWQGSN 213

  Fly   226 HLKQEVPSIKTSSGRQRRGMNTNRKCNECNPEPKNFGQEEFSYFGYAVSSGYFDSSNLSTVLY-- 288
            .:.|.    .|:...:.....||...|              .|.||.|...       |.||:
 Frog   214 FILQR----DTAWDLKEIYYPTNNTFN--------------IYMGYTVQVN-------SRVLHKD 253

  Fly   289 ----VATAPRGNNQFGEAYIFDIYEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAP 349
                |::|||..:: |..::.|:.::.:...|...|...|.|||.::...|||.||..|:::.||
 Frog   254 QVTVVSSAPRWESK-GAVFLLDVQKNIMVVKHVLNGQQVGSYFGSAIALADLNNDGWQDIVVGAP 317

  Fly   350 LYALRNSYDDGAIYVFINKGSFTFEER---IIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAP 411
            .|..|.....||:||:.|...| |.::   ::...:.||  ||..|:.|||||:||:.|:|||||
 Frog   318 YYFDRKEEIGGAVYVYNNVAGF-FNDKAAMVLHGSSFSG--FGFALANIGDINQDGFTDLAVGAP 379

  Fly   412 FAGNGSVFIYLGSENGLRDPPSQCLDAPSQQPSKYGSYM-----FGHGLSRGSDIDGNGFNDFAI 471
            |.|.|.|:||..:.:|.:..|||.:|         ||.:     ||:.||.|.|:|.|.:.|..:
 Frog   380 FDGLGKVYIYNSNADGPKQEPSQVID---------GSQVANISTFGYSLSGGLDVDDNAYPDLLV 435

  Fly   472 GAPNAEAVYLYRAYPVVKIHAIIKPKLQNVNPEE----ERVNITVC--YRLSSKSDSKAKALMEQ 530
            |: ..:.:.|.|:.||:.|....|.....|:|.:    ..:::.||  |.||:.:.:..|.:..|
 Frog   436 GS-LTDRIALLRSRPVINISKDFKVTPTLVDPSKCSNTSCIDVLVCFSYTLSTGNAAYRKNITLQ 499

  Fly   531 ELVIRIDIDTK-SKIKLAVFDEEHGS--QMSFKAKAFHEEICSEFQIEM--DKRAKFTPIALEMQ 590
             ..:..|.|.: .::|   |....|:  |..|   :..:..|...|:.:  :.|.|..||::.::
 Frog   500 -YTLEADHDRRPPRVK---FQGASGAVYQGLF---SMPDTKCQNVQLLLLDNIRDKLHPISISLK 557

  Fly   591 YELSKK-------IPNSGDFCEDCAVVDPAEPKFVTEYITFNTGCATD-VCVADLK--------- 638
            |.:.::       :.:..:|    .|:...:..|....|.|...|.:| ||.::|:
 Frog   558 YSILEREARGRSAVRSLDNF----PVLSEDQSNFQELEIHFQKECGSDNVCRSNLQMQYEYVVGN 618

  Fly   639 --ISCINASSTLVLGTTAVLRLTYNI--------TNNGEFAYHPKFSVTNSAGLSLAQV--PGNC 691
              :|.:|.|..|.. .::|.::..|:        |:..:.|:....::|....|..:.|  |..|
 Frog   619 APLSKVNGSQILHY-DSSVNKVNLNVIVTNFPSATSPADDAHEAVLNITIPPELFFSSVRPPLAC 682

  Fly   692 KVNEAVMVCDLNHGQRMAKGDTDSLTISFDVRQLRGRSLEI----QAEVLSARDESNPENNKLTN 752
            .:.|.: :|:|  |....:.....:||.|:|..:..::.|:    |...||.:|:.:.|..||..
 Frog   683 TLKETI-ICEL--GFPFKRNQKAEITIVFEVVGISLKTREVVAGLQLSTLSKQDDLHEEYAKLLV 744

  Fly   753 VLSLREKADIYVSGVQT--NDHVVLKESPYTAE-----------VVNYYEIKSHGPST-LENLTV 803
            ..:|:....:..|.:||  :.:|:.:.:..|.:           |:||.|     |.| |..|.:
 Frog   745 DYTLKISFSVQPSHIQTYFSGNVMGESAMKTVQDVGSPVEFSFTVINYGE-----PLTSLATLFI 804

  Fly   804 SLYIP--------VAYKTPDSTNVKHIVTSSPKIQSKYAHKIMPINFIDQNNALANNFAIDHDQS 860
            :...|        :.|.|....|     |.:.|........|.|:|.              :...
 Frog   805 AFNWPHEVANGKWLLYPTEVLVN-----TGTEKACHPSGDVINPLNL--------------NVSE 850

  Fly   861 TLLFSATPQHENVGNLSGIVEQNPSISLLNEDLPVNNTLVLNCQDTNVTLCVPVEIRLENGLQLK 925
            ||:.....|          :::.|.:..|......::..||.|.....| ||.....| |.:|.:
 Frog   851 TLVKRRRRQ----------IDETPDVRTLAAVRRESSEAVLKCSGGGAT-CVHFSCPL-NDMQSR 903

  Fly   926 PEELMNMTV---SFTVNLKDADDIW-----EYFVIQTDLKVHKIGDPTLS--------SFTIEKK 974
            ....|...|   :|..:.::.|.:|     |.: ::||:       ||::        |.:|:.:
 Frog   904 ATISMRGRVWNSTFLEDYRNVDRVWVMGGAELY-LKTDV-------PTINMKSQFVTFSVSIDSE 960

  Fly   975 IESNVICKHAEIAIWKIIVSVIVGILVFSAATYALYKRGFFKRA 1018
            :|..   ..||:.:|.|||||:.||::.......|:|.|||:||
 Frog   961 LEEP---PPAELPLWLIIVSVVSGIVLLGIIILLLWKCGFFRRA 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	30/75 (40%)
		Int_alpha	384..434	CDD:214549	26/49 (53%)
		Int_alpha	447..>492	CDD:214549	17/49 (35%)
		Integrin_alpha2	486..808	CDD:462478	80/379 (21%)
itga3	XP_004918665.2	Int_alpha	37..98	CDD:214549	16/64 (25%)
		Int_alpha	292..>335	CDD:214549	18/42 (43%)
		Int_alpha	352..404	CDD:214549	28/53 (53%)
		Integrin_alpha2	448..895	CDD:462478	100/496 (20%)