Protein Alignment ItgaPS4 and itga8

DIOPT Version :10

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_002939074.2
• Gene: itga8 / 100487624
• XenbaseID: XB-GENE-961825
• Length: 1081
• Species: Xenopus tropicalis
• Alignment Length: 1139
• Identity: 291/1139 - (25%)
• Similarity: 486/1139 - (42%)
• Gaps: 209/1139 - (18%)

  Fly     3 CLLVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLVI-----REKSIMVAAPRAN 62
            |.:::|:: |....:|:|:.....:|.:.|.      .||||:|:..     .:.||::.||:||
 Frog    42 CPMLMVIM-LSGVCSAFNLDVEKVTVYSGPP------DSYFGYSVDFYLPDSAKTSILIGAPKAN 99

  Fly    63 SSLEAQRNISEPGVIFRCYF----ESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDFRWLGGAMD 123
            :|   |..|.|.|.::.|.|    .:|....|::|....|.:  .|......:.|..:|.|..:
 Frog   100 TS---QPQIVEGGAVYYCPFPDTLPTGCKQIPFDITNNRNIR--LNGTKQPVEFKSNQWFGATV- 158

  Fly   124 GGTRDSDKFLVCAPRFYSINNENDYNNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTN 188
              ....:|.:.|||.:              :|.|..|       :.||.|:     ....:|..|
 Frog   159 --RAHKEKVVACAPLY--------------HWRSIKP-------ISEKDPV-----GTCYIAIQN 195

  Fly   189 LIPY--YS---------MGELGLSAHVSDD---NSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSG 239
            ...|  ||         .|:....|..|.|   |..|.:|.||...|:|.|........||..|.
 Frog   196 FSAYAEYSPCRSDLADPAGQGVCQAGFSLDFYKNGDLALGGPGSFYWQGQVFTASIADIIKDYSF 260

  Fly   240 RQRRGMNTNRKCNECNPEPKNFGQEEF--SYFGYAVSSGYFDSSNLSTVLYVATAPRGNNQFGEA 302
            :     :..||.:  ..:.....|..:  ||.||:|:.|.|...::..|  ||..|||...||
 Frog   261 K-----SIIRKIS--GEKQTKMAQSAYDDSYLGYSVAVGEFTDDSVQEV--VAGVPRGAQNFG-- 314

  Fly   303 YIFDIYEDSIYKYHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALR----NSYDDGAIY 363
            |:..|....:.....|.|:....||||:|...|:|.||..|:::.|||:..|    |..:.|.:|
 Frog   315 YVSIINSTDMTFIQNFTGDQMASYFGYTVAVSDVNNDGLDDILVGAPLFMDREFESNPREVGKVY 379

  Fly   364 VFINKGSFTFEERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAG---NGSVFIYLGSE 425
            :::.:.:..|.:..:.......||||:.::.:||:|:|||||:|||:||||   .|.||||.|:.
 Frog   380 LYMQESALEFRDPQVLKGTEVFGRFGSAIAHLGDLNQDGYNDIAVGSPFAGEDRKGRVFIYNGNS 444

  Fly   426 NGLRDPPSQCLD-APSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVK 489
            |||....||.|: |.:.|....|   ||..|...||||.|.:.|..:||..|....:|||.||:.
 Frog   445 NGLNTDTSQILEGAWASQSMPAG---FGFTLRGDSDIDKNDYPDLIVGAFGAGKAVVYRARPVIT 506

  Fly   490 IHA--IIKPKLQNVNPEEER------------VNITVCYRLSSKSDSKAKALMEQELVIRIDID- 539
            :.|  ::.|.:  :|||.:.            ..:.||..:|.:|       :...:|::.|::
 Frog   507 VDAQLLLHPMI--LNPENKTCQLPNSEFLVTCFTVRVCVTVSGQS-------IPSNIVVKADLEL 562

  Fly   540 ----TKSKIKLAVFDEEHGSQMSFKAKAFHEEI--CSEFQI----EMDKRAKFTPIALEMQYELS 594
                .|..:|..:|.|.|.:..||......:.:  |.:|.:    |.:.|.|.|||::.:.|.|.
 Frog   563 DWLKQKGAVKRTLFMESHQAHHSFDLIINKQRLSQCLDFLVYLREESEFRDKLTPISVNLNYSLD 627

  Fly   595 KKIPNSGDFCEDCAVVDPAEPKFVTEYITFNTGCATD-VCVADLKISCINASSTLVLGTTAVLRL 658
            :. ...|| .|...:::..:...:.|.......|..| :|:.|||:|.....:.||:|....:..
 Frog   628 ES-AYLGD-QELKPILNRYKKATIQEQAHILVDCGEDNMCIPDLKLSARPDKNQLVIGEENHILF 690

  Fly   659 TYNITNNGEFAYHPKFSV------------TNSAGLSLAQVPGNCKV---NEA-VMVCDLNHGQR 707
            ..|..|.||.||..:..:            .|..||...    ||:.   ||: ::||||  |..
 Frog   691 IINTKNQGEGAYEAELRMIIPPEADYVGIERNMEGLRQL----NCEYKMENESRLVVCDL--GNP 749

  Fly   708 MAKGDTDSLTISFDVRQLRGRSLEIQAEVLSARDESNPENNKLTNVLSLREKADIYVSGVQTNDH 772
            |..|...|:.:.|.|::|...........:.:.::.||.:|.::..:::...|.:.:.||.....
 Frog   750 MVAGTNLSVGLRFVVQRLETVDAITFDLYIKSSNKDNPNSNFVSLQVNITAVAQVEIRGVSHPPQ 814

  Fly   773 VVL-------KESPYTAE-----VVNYYEIKSHGPSTLENLTVSLYIPVAYKTPDSTNVKHIVTS 825
            ::|       ||.|...:     |.:.||:.:.|||.:....:::..|...:......|.||.|.
 Frog   815 IILPIPNWEPKEKPSEEKDVGPLVQHIYELHNIGPSAISETQLNVGWPSQSRDEFLLYVFHIQTE 879

  Fly   826 SP-KIQSKYAHKIMPINFIDQNN-----ALANNFAIDHDQSTLLFSATPQHENVGNLSGIVEQNP 884
            .| |.|:..|...:.|...:..:     |...|.::.|                    .:..::.
 Frog   880 GPLKCQAGSAINTLNIKPSEPEDTPELAAFLRNTSVSH--------------------AVSRRDV 924

  Fly   885 SISLLNEDLPVNNTLVLNCQDTNVTLCVPVEIRLEN--GLQLKPEELMNMTVSFTVNLKDADDIW 947
            :::.....:| ..|.:|||  |||. |:.:..::.:  |.|....::.:...:.|. |:..:|.:
 Frog   925 AVAEALRHIP-TPTKLLNC--TNVK-CLMISCKVGHLGGGQRAVVKIRSRLWAPTF-LQRKNDYY 984

  Fly   948 EYFVIQTDLKVHK----IGDPTLSSFTIEKKIESNVICKHAEIA----IWKIIVSVIVGILVFSA 1004
            . .:.....:|.|    |....|.:.||  .|:::||.....|:    :|.|::::::||||.:.
 Frog   985 S-LIANVSFEVKKMPYDIQPAKLPAATI--LIKTSVIWATPNISFAIPLWVILLAILLGILVLAI 1046

  Fly  1005 ATYALYKRGFFKRA------IKDDLKQLIRDSFE 1032
            .|..::|.|||.||      :.||.:||...:.|
 Frog  1047 LTLVMWKCGFFDRARPPQDDVADDTQQLTNKTAE 1080

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	FG-GAP_3	335..408	CDD:433275	25/76 (33%)
		Int_alpha	384..434	CDD:214549	28/52 (54%)
		Int_alpha	447..>492	CDD:214549	18/44 (41%)
		Integrin_alpha2	486..808	CDD:462478	84/375 (22%)
itga8	XP_002939074.2	Int_alpha	71..130	CDD:214549	20/67 (30%)
		Int_alpha	335..>385	CDD:214549	17/49 (35%)
		Int_alpha	401..455	CDD:214549	30/53 (57%)
		Int_alpha	468..510	CDD:214549	17/41 (41%)
		Integrin_alpha2	502..952	CDD:462478	106/490 (22%)