Protein Alignment ItgaPS4 and itgae.1

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_002664631.3
• Gene: itgae.1 / 100333951
• ZFINID: ZDB-GENE-131121-125
• Length: 547
• Species: Danio rerio
• Alignment Length: 732
• Identity: 138/732 - (18%)
• Similarity: 253/732 - (34%)
• Gaps: 267/732 - (36%)

  Fly     4 LLVIVLLALQSEINAYNISPYPNSVLNFPELEGNRRSSYFGFSLVIREKSIMVAAPRANSSLEAQ 68
            ||.:::|...:..| ..|||    |.:|     ......||.:::..:..|.|.:|..
Zfish     5 LLFVMVLCNAAGFN-IQISP----VKHF-----TNEDPLFGQTIIQAKDGIFVPSPTY------- 52

  Fly    69 RNISEPGVIFRCYFESGNNCSPYNIDTKGNYKGM---PNDGLLTAKNKDFRWLGGAMDGGTRDSD 130
                  |.:|:|..:  |.|:..||:.: |.|||   .:...||::                  :
Zfish    53 ------GRLFKCTLD--NECTKVNINDE-NPKGMRPVASVASLTSQ------------------E 90

  Fly   131 KFLVCAPRFYSINNENDYNNGMCYWLSDTPKNIDSTEVMEKWPLRIEKKQVLKLADTNLIPYYSM 195
            :.:|...:..:.|...:|.||:|..:|.:.|       ::.:|..::..:
Zfish    91 QHVVMCNQVRTENRGTEYLNGICTLVSPSGK-------VKLYPAELDNNK--------------- 133

  Fly   196 GELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSIKTSSGRQRRGMNTNRKCNECNPEPKN 260
               ..:.:.:::|:|...|.  |:|..|:     |:..:...||                    :
Zfish   134 ---NNNNNNNNNNNKYQGGR--INQGPGT-----EIAFVLDGSG--------------------S 168

  Fly   261 FGQEEFSY---FGYAVSSGY----FDSSNLSTVLYVATAPRGNNQFGEAYIFDIYED---SIYKY 315
            ...::|..   |.|.|.|..    || .|.:.|.|      |:....|..:.| .||   |:.|.
Zfish   169 IQDDDFQKAKDFIYNVMSNVWKTCFD-CNFAIVQY------GSLIRTELSLLD-NEDRVGSLLKV 225

  Fly   316 HEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLYALRNSYDDGA-IYVFINKGSFTFEERIIR 379
            .:.:     :.:..:..|..:| ...||:.|..     ..|.|:.| |.:.::.|      :|:.
Zfish   226 KQIK-----QIYNLTKTASAIN-HVLTDIFIPE-----NGSKDNSAKIIIVLSDG------KILG 273

  Fly   380 SPAGSGGRFGTTLSRIGDINK---DGYNDVAVGAPFAGNGSVFIYLGSENGLRDPPSQCLDAPSQ 441
            .|        .||..:  :||   .|....::|   .|:|.:               :.|||..:
Zfish   274 DP--------MTLDEV--LNKPQMKGVTRYSIG---VGDGIL---------------KNLDATEE 310

  Fly   442 -----QPSKY---GSYM----FGHGLSRG----SD--------IDGNGF---NDFAIGAPNAEAV 479
                 .|.||   .||.    ....|.||    .|        :||:|.   :||     .....
Zfish   311 MMQIADPGKYYNVSSYRALNDIVSSLERGIIGTKDPGTEIAFVLDGSGSIQDDDF-----QKAKD 370

  Fly   480 YLYRA------------YPVVKIHAIIKPKLQNVNPEEERVNITVCYRLSSKSDSKAKALMEQEL 532
            ::|..            :.:|:..::|:.:|                 |...::.:|.:|::.:.
Zfish   371 FIYNVMSNVWKTCFDCNFAIVQYGSLIRTEL-----------------LLLDNEDRAGSLLKVKQ 418

  Fly   533 VIRIDIDTK-----SKIKLAVFDEEHGSQMSFKAKAFHEEICSEFQIEMDKRAKFTPIALE---- 588
            :.:|...||     :.:...:|..|.||:.: .||..  .:.|:.:|..|      |:.|:
Zfish   419 IKQIYNLTKTASAINHVLTDIFIPEKGSKNN-TAKII--IVLSDGEILED------PMTLDEVLN 474

  Fly   589 -------MQYELS-----KKIPNSGDFCEDCAVVDPAEPKFVTEYITFNTGCATDVCVADLKISC 641
                   .:|.:.     .|.||:  ..|...:.||.:...|:.|     |...|: ::.|:...
Zfish   475 KPQMKGVTRYSIGVGDGILKKPNA--VKEMMQIADPGKYYSVSSY-----GALNDI-LSSLEREI 531

  Fly   642 INASSTLVLGTTAVLRL 658
            |......|  ||.||::
Zfish   532 IGTEGDSV--TTTVLQI 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	16/76 (21%)
		Int_alpha	384..434	CDD:214549	8/52 (15%)
		Int_alpha	447..>492	CDD:214549	13/75 (17%)
		Integrin_alpha2	484..808	CDD:285619	38/208 (18%)
itgae.1	XP_002664631.3	vWFA	157..332	CDD:294047	48/252 (19%)
		vWFA	348..523	CDD:294047	36/212 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574898
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740