Protein Alignment ItgaPS4 and itga3b

DIOPT Version :9

• Sequence 1: NP_611025.2
• Gene: ItgaPS4 / 36693
• FlyBaseID: FBgn0034005
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001177238.1
• Gene: itga3b / 100331874
• ZFINID: ZDB-GENE-050411-55
• Length: 1041
• Species: Danio rerio
• Alignment Length: 1217
• Identity: 279/1217 - (22%)
• Similarity: 470/1217 - (38%)
• Gaps: 368/1217 - (30%)

  Fly     4 LLVIVLLALQSEINAYNISPYPNSVLNFPEL-EGNRRSSYFGFSLVIREKS-------IMVAAPR 60
            |.|.|:.|:|:. ..:||.      :.||.: ||..:.|.||||:.:.:::       ::|.||:
Zfish     8 LCVFVICAIQTN-TGFNID------VQFPVIKEGKTKGSLFGFSVALHKQTEKAKKNLLLVGAPQ 65

  Fly    61 ANSSLEAQR-NISEPGVIFRCYFESGNNCSPYNIDTKGNYKGMPNDGLLTAKNKDF---RWLGGA 121
            ..:..:..: .|:|.|.::.|..       ..|:|..|:.     |.:...|:.|.   .|||..
Zfish    66 EKAQPQLSKFKINETGAVYYCPI-------TVNLDDCGSM-----DLISPPKSTDMLEGMWLGVT 118

  Fly   122 MDGGTRDSDKFLVCAPRF-----------------YSINNENDYNNGMCYWLSDTPKNIDSTEVM 169
            : ...|:..:.|.|..|:                 |...|:..|:.. .||.|:|.:..|...
Zfish   119 V-ASQRNGGRVLACGHRYVKKLLGAEEQQRMVGKCYVRGNDLSYDPS-DYWQSETYELCDFNH-- 179

  Fly   170 EKWPLRIEKKQVLKLADTNLIPYYSMGELGLSAHVSDDNSKLLMGAPGIDQWKGSVHLKQEVPSI 234
                            |.:|   ..|..:|:|..:::.:  :..|.||...|:|:||:
Zfish   180 ----------------DQDL---EGMCNMGISGGMTEKD--VYFGTPGSFTWQGTVHM------- 216

  Fly   235 KTSSGRQRRGMNTNRKCNECNPE------PKNF---GQEEFS-YFGYAVSSG--YFDSSNLSTVL 287
                           ||.:.:.:      .::|   |:::|: |.||:|...  ..|.|..:.|:
Zfish   217 ---------------KCRDTDSDYAGDANDRSFGKLGEDKFNIYIGYSVLEDIKLLDRSVFTVVM 266

  Fly   288 YVATAPRGNNQFGEAYIFDIYEDSIYK-YHEFRGNHFGEYFGYSVLAEDLNGDGKTDVIISAPLY 351
               .|||  ::|..:.|....:|.|.| .....|...|.|||..:...|||.|...|:|:.||.|
Zfish   267 ---GAPR--DEFKGSVILADKQDLILKQLMNITGEQIGSYFGSCLAVTDLNNDDWNDLIVGAPFY 326

  Fly   352 ALRNSYDDGAIYVFINK-GSFTFE-ERIIRSPAGSGGRFGTTLSRIGDINKDGYNDVAVGAPFAG 414
            ..|...:.||:|:|:|: |||..: ..:::...|||  ||..::.:||:|:||:.|:||||||..
Zfish   327 FDRYKEEGGAVYIFMNENGSFQKKASLVLKGKKGSG--FGFAIAAVGDVNQDGFQDIAVGAPFQD 389

  Fly   415 NGSVFIYLGSENGLRDPPSQCLDAPSQQPSKYGSYMFGHGLSRGSDIDGNGFNDFAIGAPNAEAV 479
            :|.|:|::||::|:...|||.::..|..||  |...||:.||.|.|:|||.:.|..:|:.: :.:
Zfish   390 SGKVYIWMGSKSGITKEPSQVIEGKSLGPS--GFQTFGYSLSGGMDMDGNDYPDILVGSLD-DRI 451

  Fly   480 YLYRAYPVVKI--HAIIKPKLQNVNPEE---ERVNITVCYRLSSKSDSKAKALMEQELVIRIDID 539
            .|.|:.||:.:  :..::||:  |.|.:   ..:.:.||:   |.:.|...:...:|:.::..||
Zfish   452 ALLRSRPVIHLSKNFTVEPKI--VIPSQCGNSCIKVKVCF---SYTLSNGNSNFRKEITVKFTID 511

  Fly   540 ---TKSKIKLAVFDEEHGS---QMSFKAKAFHEEICSEFQIEMDKRA--KFTPIALEMQYELSKK 596
               .:...::...|.:..:   .:||.|.:     |.|.::.::...  |..||...:...|:::
Zfish   512 ADQNRRGARVRFIDNKQSTFTGLLSFSASS-----CQELELSVNNPVTDKLQPIVFSLNVSLNQQ 571

  Fly   597 IPNSGDFCEDC----------AVVDPAEPKFVTEYITFNTGCATD-VCVADLKISCINA------ 644
            ...:....:..          .:.|.||       |.|:..|..| .|.::|::....|
Zfish   572 KAEAQQTLQSLDSFPVLSGQQILTDKAE-------INFHKECGDDNRCSSNLQLKARFADENYNP 629

  Fly   645 --SSTLVLGTTA---VLRL--------------TYNITNNGEFAYHPKFS-VTNSAGLSLAQVPG 689
              |.||...:..   ||.:              .:..|.|....|..|:| |...||..:
Zfish   630 FPSQTLEFSSNVKKLVLMVEVSNTADENKPAEDAHQATLNISIPYSLKYSGVRPPAGFDM----- 689

  Fly   690 NCKVNEAVMVCDLNHGQRMAKGDTDSLTISFDV-----------RQLRGRSLEIQAEVLSARDES 743
            .|..:||| :|||  |.........|..|.|:.           .||:..::..||::.......
Zfish   690 ECSADEAV-ICDL--GNPFKSNQKVSFIIIFETSGITLYTEQIQSQLQLSTISEQADLFPVLVTL 751

  Fly   744 NPENNKLT---------------NVL---SLREKADI-----YVSGVQTNDHVVLKES------- 778
            |.:|..||               ||:   ::...:|:     :|..||     ||.|.
Zfish   752 NVKNTILTTFSLEKLIIDTSFSGNVIGESAMSSTSDVGSPLEFVFRVQ-----VLGEPLGDLGTL 811

  Fly   779 ------PYT----------AEVVNYYEIKSH--GPSTLE---NLTVSLYIPVAYKTPDSTNVKHI 822
                  ||.          .|:|.....:||  .|..:.   |||:|       |.....|.:.:
Zfish   812 VIDFDWPYAVANGKWLLYLTEIVIKGSSESHCVPPGNIVNYLNLTLS-------KEGTKRNKREV 869

  Fly   823 VTSSPKIQS--------KYAHKIMPINFID--QNNALANNFAIDHDQSTLLFSATPQHENVGNLS 877
            .:..|..::        |.||      |:|  :..||...|
Zfish   870 DSGFPHAEASVTVLATRKVAH------FLDCSKKTALCQTF------------------------ 904

  Fly   878 GIVEQNPSISLLNEDLPV---------NNTLVLNCQDTNVTLCVPVEIRLENGLQL---KPE-EL 929
                   |..|||.....         |.||:     .:....:.||::.:..|:|   ||. ::
Zfish   905 -------SCPLLNMSTQAEVRVRARVWNGTLL-----EDYAKALRVEVKGQATLRLLTDKPAIKM 957

  Fly   930 MNMTVSFTVNLKDADDIWEYFVIQTDLKVHKIGDPTLSSFTIEKKIESNVICKHAEIAIWKIIVS 994
            .|.|..|:||:                      ||.|...|            ..|:.:|.|||:
Zfish   958 DNQTREFSVNI----------------------DPVLGEET------------PYEVPLWIIIVA 988

  Fly   995 VIVGILVFSAATYALYKRGFFKRAIKDDLKQLIRDSFEDGIIRTEME 1041
            .:.|||:....:..|:|.|||:||.:.::.:......|..|..:|.|
Zfish   989 AVAGILLLGIISLILWKCGFFRRASRREMYEAKSQKAEIKIQPSETE 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS4	NP_611025.2	VCBS	335..408	CDD:290251	29/74 (39%)
		Int_alpha	384..434	CDD:214549	23/49 (47%)
		Int_alpha	447..>492	CDD:214549	16/46 (35%)
		Integrin_alpha2	484..808	CDD:285619	85/435 (20%)
itga3b	NP_001177238.1	Int_alpha	38..101	CDD:214549	16/74 (22%)
		Int_alpha	298..346	CDD:214549	19/47 (40%)
		Int_alpha	360..411	CDD:214549	26/52 (50%)
		Integrin_alpha2	456..906	CDD:285619	96/523 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574939
Domainoid	1	1.000	61	1.000	Domainoid score	I10420
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740