Protein Alignment scb and itga11a

DIOPT Version :10

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: NP_001166098.2
• Gene: itga11a / 541475
• ZFINID: ZDB-GENE-050324-1
• Length: 1190
• Species: Danio rerio
• Alignment Length: 1380
• Identity: 287/1380 - (20%)
• Similarity: 463/1380 - (33%)
• Gaps: 506/1380 - (36%)

  Fly    23 EAFNFMPRPSRVINSPKHLKFHINQTRSSYFGYT----LVIRQTSIIVGAPRAQSTLESQRTINE 83
            :.||...|..|:|..|          |.:.||||    :...|..::||||     ||:... ::
Zfish    21 DCFNIDTRNHRIIKGP----------RQTQFGYTVQQHIAGGQKWLLVGAP-----LETNGQ-HQ 69

  Fly    84 TGAIYRCSLTNGVCSPYVLDSRGNVDAPYSEYTFDSERKDFQWLGGSMDGGTKDTDKLLVCAPRF 148
            ||.:|:|.|:.....|    |...::......|..||||:...||.::....|| :..:.|.|.:
Zfish    70 TGDVYKCPLSRRSGGP----SCSKLNLGKISLTNVSERKERMRLGMTLSSNPKD-NSFVACGPLW 129

  Fly   149 YAPSSRDNHLHGVCYWVN------NTVASTPQ-----------------------------HVTR 178
            ........:..|:|..||      .|:|...|                             ::.|
Zfish   130 SYECGSSYYSTGICSRVNASFKFSRTIAPAFQRCETYMDIVIVLDGSNSIYPWNEVQDFLINILR 194

  Fly   179 --------------------ISPLRL---------------------------------KSEQVK 190
                                :|..:|                                 :||..|
Zfish   195 KFYVGPGQIQVGVLQYGEKVVSEFQLNDFRSVEDVVKAARKIGQRGGEETNTALGINVARSEAFK 259

  Fly   191 E-------------------------------EDNG----------------------------- 195
            :                               |.:|
Zfish   260 QGGRRGAKKVMIVITDGESHDSADLQQVIEESEKDGITRYAIAVLGYYNRRGINPEAFLNEIKYI 324

  Fly   196 -------------------------------------NKASFFYIMGELGLSAHVADDNTKFLIG 223
                                                 |..:|...|.:.|.|.|..:|.  .|:|
Zfish   325 ASDPDDKHFFNVTDEAALKDIVDALGERIFSLEGTSKNGTAFGLQMSQAGFSTHTVEDG--ILVG 387

  Fly   224 APGINTWRGSVILYRQVDPVDNPTASRRDTSKALRRTYRDVDSNDYTPEHYAPEIPTPGLWGQEE 288
            |.|...|.|:|:...:...|..|.:|                        |..|.|       ||
Zfish   388 AVGAYDWNGAVLKETRQGKVVPPKSS------------------------YEQEFP-------EE 421

  Fly   289 ----DSYFGYAVSSGFFDSSNPTKLLYVATAPQANKQSGEAYIFDVRGK-SIHKYHVFRGEQFGE 348
                .:|.||.|:|.....|..   ||||.||:.| .:|:..||.::.. .:...|..:|:|.|.
Zfish   422 LKNHGAYLGYTVTSVVSARSGQ---LYVAGAPRFN-HTGKVIIFTLKNTGELTILHSLKGQQIGS 482

  Fly   349 YFGYSVLAEDLNGDGKTD-VIVSAPQHALEDSHDNGAIYVFINKGFFNFERQILRSPVETM---- 408
            |:|..:...|::.||.|| ::|:||.. .....:.|.:|::   ......|.||...:|.:
Zfish   483 YYGSEIAPVDIDNDGVTDNLLVAAPMF-FSGGWEKGKVYIY---RVTEQPRFILEGSLEVLDQGQ 543

  Fly   409 -ARFGTALSRLGDINHDGYNDVAVGAPFAGN--GTVFIYLGSENGLRDQPSQRLDAPSQQPSKYG 470
             ||||:||:.:.|:|.|.:|||.||||...:  |.::||....|.:..:..||:.|....|   |
Zfish   544 NARFGSALAPVPDLNGDSFNDVVVGAPLEDDHKGAIYIYHSQRNRILRKYKQRIGAVQLGP---G 605

  Fly   471 SHMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKVHATVKSESREI--------KPE 527
            ...||..:....|::|:...|.|:|:..| ||.|: :..|:::::.|:.|..:|        :..
Zfish   606 LQYFGRSIHGKMDMNGDDLVDLAVGSLGA-AVLLW-SRSVIRINSVVRFEPSKINIFNKDCRRGG 668

  Fly   528 QEKVKITACYRLSTTSTDKLVQEQELAIRIAMDKQLKRVKFTQTQTNEISFKVNANFGEQCRDFE 592
            ::...::|...|:.||...:...||:|:|                       .:|.|.|:
Zfish   669 KDVTCMSAIVCLNVTSRTPINPSQEIALR-----------------------YSAFFEEK----- 705

  Fly   593 TQVRYSEKDIFTPIDLEMHYELTKKVPDSEEFC--------ETC--------------------A 629
               |::.:.:|...|.:....||  :...||.|        ||.                    .
Zfish   706 ---RFNPRAVFDDPDRQQPQNLT--LLPGEETCDHIYFHVMETTDYARPIIFTVETELLDLYHGP 765

  Fly   630 IVDPTEPKVSTQNIIFSTGC-ATDVCTADLQLR---------------------------SKDVS 666
            ::|.:.|......:.|..|| ..|.|..||.|:                           |.|.|
Zfish   766 VLDDSWPTTVKTQLPFWNGCDEDDHCVPDLLLQAHTDLMNRQQFCGQAFRAASLLCQGHTSTDPS 830

  Fly   667 PTYILGSADTLRLNYEITNIGETAYLPQFNVTSTSRLAFAQVPGNCKVVDAVMVCDLNRGRPLAK 731
            ...|.||...:.::..:.|.||.||..:.|:|.|..|.|:.:                    :.|
Zfish   831 ERIIEGSRRKMVVDVRLENRGENAYGAKLNITYTQNLRFSSL--------------------IVK 875

  Fly   732 GDTDSVTISFDVSQLSGQSLIIHAEVFSTG---YEQ-----NPTDNRQTNVIGLKEFTEIDASGG 788
            .::|                 ||.:..:..   ||:     .|....::.||...|| |...|..
Zfish   876 DNSD-----------------IHIDCRNENKRKYEKTCNISEPFMRAKSQVIFRLEF-EFSHSEL 922

  Fly   789 QTNSQIDLEHYSNSAEIV---NNYEIKSNGPSVIEQLTVSFYIPIAYKVAGSTAI------IPII 844
            ..:.:|.||..|...|::   |:.||..|.....:.|....:.|..|::....::      .|..
Zfish   923 LDHVRIILEVTSEGEEVILYDNSNEIFYNLKYEADLLFTRDFYPTRYELKPDLSLEKADDFNPPF 987

  Fly   845 NVTSLKMQASYDSQLLSIDLYDQNNTMLVVDPVEVTTTLSGGLERTVITQNRQSYDIHTSGHVHQ 909
            |.|         .|:.::..:...:..|.:...|||   ..|      .|..|..|.|..
Zfish   988 NFT---------FQIQNLGYFPIQDLQLYIAIPEVT---KNG------NQLLQIRDFHID----- 1029

  Fly   910 TMEVLDTSMVATASMSRKRRDLKALTANREQYARISNVKAHDLLSDDFKGKLPVNRTI-VFNCRD 973
              ::..:..:....::..|       |:.|..:|.|.:...:.|:      :||..|: :.:.||
Zfish  1030 --QIGGSQCIPPQHVAHSR-------ASPEDLSRTSRLNYSNTLA------VPVQCTVNLPSYRD 1079

  Fly   974 PEMTICVRAEMR---VHFRPEKSINLNMRYSVDLNEVNAILVDPWEYFVILTDLKLQKKGDPTST 1035
              :::.:...:|   :|....|::.|....||:||                          |:|.
Zfish  1080 --VSVKIGGSLRTDALHALKFKTLELVTTASVELN--------------------------PSSP 1116

  Fly  1036 SFSINRRIEPNI---ISKHQETGLPIWIIIVSVIGGLLLLSAISYLLYKFGFFNRTKKDELDRLV 1097
            .|....|...:|   |.|.::..:||||||.|.:|||||||.:...|:|.|||.|.|:.|
Zfish  1117 MFLPEERPVRHIILEIRKEEDYRVPIWIIIGSTLGGLLLLSLLILALWKLGFFQRQKRRE----- 1176

  Fly  1098 QQNPVEPEAENLNSG 1112
                   ||||..:|
Zfish  1177 -------EAENEVNG 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	17/55 (31%)
		FG-GAP	350..388	CDD:460357	11/38 (29%)
		Int_alpha	409..459	CDD:214549	21/51 (41%)
		Int_alpha	473..>515	CDD:214549	12/41 (29%)
		Integrin_alpha2	509..829	CDD:462478	74/394 (19%)
itga11a	NP_001166098.2	None