DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scb and GPLD1

DIOPT Version :9

Sequence 1:	NP_523750.2	Gene:	scb / 36692	FlyBaseID:	FBgn0286785	Length:	1115	Species:	Drosophila melanogaster
Sequence 2:	XP_016866242.1	Gene:	GPLD1 / 2822	HGNCID:	4459	Length:	850	Species:	Homo sapiens

Alignment Length:	236	Identity:	60/236 - (25%)
Similarity:	100/236 - (42%)	Gaps:	40/236 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 DSYFGYAVSSGFF--DSSNPTKLLYVATAPQANKQSGEAYIFDVRGKSIHKYHVFRGEQFGEYF- 350
            |....|.....||  :|..|..:.::..|.:.|.::    :| :.|..:.:.||  ......||
Human   327 DRNINYTERGVFFSVNSWTPDSMSFIYKALERNIRT----MF-IGGSQLSQKHV--SSPLASYFL 384

  Fly   351 -------GYSVLAEDLNGDGKTDVIVSAPQHALEDSHDNGAIYVFINKGF--------FNFERQI 400
                   |:::.:.|||.||..|::|.||.::.......|.:|:......        .:.|...
Human   385 SFPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHR 449

  Fly   401 LRSPVETMARFGTALSRLGDINHDGYNDVAVGAPFAGN------GTVFIYLGS-ENGLRDQPSQR 458
            :....:...|||:||:.| |.|.||..|:|||||..|:      |.|::|.|| :.|:...|:..
Human   450 ILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSPNIT 513

  Fly   459 LDAPSQQPSKYGSHMFGHGLSRGSDIDGNGFNDFAIGAPNA 499
            :.......:      .|..| ..:|::|:...|..||:|.|
Human   514 ISCQDIYCN------LGWTL-LAADVNGDSEPDLVIGSPFA 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549
		FG-GAP	350..388	CDD:280083	13/45 (29%)
		Int_alpha	409..459	CDD:214549	24/56 (43%)
		Int_alpha	473..>515	CDD:214549	9/27 (33%)
		Integrin_alpha2	507..829	CDD:285619
GPLD1	XP_016866242.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900