Protein Alignment scb and if

DIOPT Version :10

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: XP_061518066.1
• Gene: if / 1272247
• VectorBaseID: AGAMI1_012318
• Length: 1538
• Species: Anopheles gambiae
• Alignment Length: 995
• Identity: 247/995 - (24%)
• Similarity: 405/995 - (40%)
• Gaps: 212/995 - (21%)

  Fly    11 IFLALLALISHIEAFNFMPRPSRVINSPKHLKFHINQTRSSYFGYTLVIRQTS----IIVGAPRA 71
            ::|...|...:::..||:.:.    ..|           ||.||:::.:.:..    :|||||.|
Mosquito    33 VWLGQTATAFNLDTINFILKE----GDP-----------SSMFGFSVALHREQNNSWVIVGAPTA 82

  Fly    72 QSTLESQRTINETGAIYRCSLTNGV-CSPYVLDSRGNVDAPYSEYTFDSERKDFQWLGGSMDGGT 135
            .:   ||..:.:.||:|||.:.:.. |.....|::||.   |::.....:.|..||.|.::....
Mosquito    83 NT---SQPGVIKGGAVYRCDIYDDYRCYLLPFDTKGNT---YNDQNEQIDTKSNQWFGATVASAG 141

  Fly   136 KDTDKLLVCAPRFYAPSSRDNHLH-----GVCYWVNNTVASTPQHVTRISPLRLKSEQVKEEDNG 195
            .| ..|:.||||:.....:.....     |.||...|.:    |:...|||.|
Mosquito   142 ID-GPLVACAPRYVFHQLQPRKAERVEPVGTCYLAKNNM----QNFEDISPCR------------ 189

  Fly   196 NKASF--FYIMG--ELGLSAHVADDNTKFLIGAPGINTWRGS--------VILYR---------- 238
              .::  ::..|  :.|.||.:.:|.::..|||||...|:|.        |..|:
Mosquito   190 --TAYWGYHRQGSCQAGFSAAITNDGSRLFIGAPGSYYWQGQMYSINTDVVFPYKPPRYGHFGEG 252

  Fly   239 -QV------DPVDNPTASRRDTSKALRRTYRDVDSNDYTPEHYAPEIPTPGLWGQEEDSYFGYAV 296
             |:      :|.|....:..||.|                               |:|||.||:.
Mosquito   253 GQIYSFSLNNPKDKVYKTLEDTKK-------------------------------EDDSYLGYSS 286

  Fly   297 SSGFFDSSNPTKLLYVATAPQANKQSGEAYIFDVRGKSIHKYHVFRGEQFGEYFGYSVLAEDLNG 361
            ::|.|:... |:.:.|. .|:..:..|:..|:   ..::.......|||.|.|||||:.|.|::|
Mosquito   287 TTGDFNGDG-TQGVAVG-KPRGARLLGKVLIY---SWNMTNQQNITGEQIGAYFGYSLAAVDVDG 346

  Fly   362 DGKTDVIVSAPQHA---LEDSHDNGAIYVFINKGFFN--FERQILRSPVETMARFGTALSRLGDI 421
            |...|:|:.||.:.   .|..::.|.:|:.......:  |.....|..|.:.||||.|:..|.|:
Mosquito   347 DKLDDLIIGAPMYTEPNNEGKYETGRVYIMYQGAAADGRFRELDTRDGVNSKARFGLAVCSLADL 411

  Fly   422 NHDGYNDVAVGAPF---AGNGTVFIYLGSENGLRDQPSQRLDAPSQQPSKYGSHMFGHGLSRGSD 483
            |.|||.|.|||||:   .|.|.|:|:.||..|...:.||.:.|.........| .||..||.|.|
Mosquito   412 NLDGYGDFAVGAPYDGPNGRGAVYIFYGSRTGPLAKASQVIQAEDMAGVTRLS-TFGFSLSGGID 475

  Fly   484 IDGNGFNDFAIGAPNAEAVYLYRAYPVVKVHATVKSESRE-----------IKPEQEKVKIT--- 534
            :|||.:.|..:||..::...:::|.||..:.|:...|.:.           :|...:.|..|
Mosquito   476 LDGNQYPDMVVGAYESDKALVFKARPVAAMVASTLFEPKSKLIALDVKNCALKRTNKTVPCTVVN 540

  Fly   535 ACYRLSTTSTDKLVQEQELAIRIAMDKQLKR----------VKFTQTQTNEISFKVNANFGEQCR 589
            :|.:.:..:...::   ::.|...:|.:..|          ...|:||...:     |....:|.
Mosquito   541 SCLKYNGINVPPML---DIEISWTLDARKARNPRMFFLDHEGNHTRTQLMRL-----ARGKLECI 597

  Fly   590 DFETQVRYSEKDIFTPIDLEMHYELTKKVPDSEE--FCETCAIVDPTEPKVSTQNIIFSTGCATD 652
            :.:..|..:.:|..||:::||.|.|.:.|...:.  ...|..::|.....|....|.....|..|
Mosquito   598 EDKVYVADNIRDKITPLEVEMAYGLRQNVLGRQRRPRAHTEPVLDQNRGTVQRDAINIQKNCGPD 662

  Fly   653 -VCTADLQLRSKDVSPTYILGSADTLRLNYEITNIGETAYLPQFNVTSTSRLAFAQVPGNCKVVD 716
             ||..||::..|.|. .|:|||.:.|.:...|||.||.|:...|.:...:.|.|.:|....:|.|
Mosquito   663 NVCVPDLRMEVKSVD-DYLLGSNNLLSVEVLITNRGEDAFEAGFYMAVPNGLDFRRVDRLGEVKD 726

  Fly   717 AVMVCDLNRGRPLAKGDTDSVTISFDVSQLSGQSLIIHAEV-----FSTG--------YEQNPTD 768
            ..::|       .|.....:.|:..|:........::|.:|     ||.|        .|.|.|:
Mosquito   727 VPVLC-------TAPSAATNKTLKCDIGNPLSSGKVVHFKVILAPSFSAGMGSSYDFYLETNSTN 784

  Fly   769 -----NRQTNV----IGLKEFTEIDASGGQTNSQIDLEH--YSNSAE----------IVNNYEIK 812
                 |||.||    ||:...|::..||.....|....|  |.:.||          :|:.|||:
Mosquito   785 AELDGNRQDNVMRKTIGILVQTDLAMSGVSLPDQFHYNHSEYKSLAEAKTERDIGPQVVHIYEIR 849

  Fly   813 SNGPSVIEQLTVSFYIPIAYKVAGSTAIIPIINVTSLK-----MQASYDSQL-LSIDLYDQNNTM 871
            :.|||.|::  ..|::...|:......::.::|.....     :...|.:.| |:||......:.
Mosquito   850 NEGPSTIDE--AEFFVLWPYETVDGVPLMYLLNQPETHGNIECLPTEYANPLNLAIDSALARKSF 912

  Fly   872 LVVDPVEVTT-TLSGGLERT 890
            |  |.|.|:: :.|..:.||
Mosquito   913 L--DKVGVSSASYSSSMGRT 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	17/56 (30%)
		FG-GAP	350..388	CDD:460357	15/40 (38%)
		Int_alpha	409..459	CDD:214549	26/52 (50%)
		Int_alpha	473..>515	CDD:214549	15/41 (37%)
		Integrin_alpha2	509..829	CDD:462478	90/380 (24%)
if	XP_061518066.1	None