Protein Alignment scb and itga6

DIOPT Version :9

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: XP_002934665.3
• Gene: itga6 / 100497992
• XenbaseID: XB-GENE-489982
• Length: 1095
• Species: Xenopus tropicalis
• Alignment Length: 1198
• Identity: 257/1198 - (21%)
• Similarity: 486/1198 - (40%)
• Gaps: 338/1198 - (28%)

  Fly    51 SYFGYTLV-------IRQTSIIVGAPRAQSTLESQRTINETGAIYRCSLT--NGVCSPYVLDSRG 106
            |.||:::.       :.:..::||:|||:: |.:|:. |.||.:|.|.:|  :..|:..:.|.
 Frog    38 SLFGFSMAMHWQLDPVNRRLLLVGSPRAKA-LPAQKA-NVTGGLYVCDITSPSPSCNRVLFDD-- 98

  Fly   107 NVDAPYSEYTFDSERKDFQWLGGSMD----GGTKDTDKLLVCAPRFYAPSS-----RDNHLHGVC 162
            :||       ..||.|:.||:|.|:.    ||     |::.||.|:...:|     .:..:.|.|
 Frog    99 SVD-------LTSESKENQWMGVSVQSQGPGG-----KIVTCAHRYERRTSVNTNYENRDITGRC 151

  Fly   163 YWVNNTVASTPQHVTRISPLRLKSEQVKEEDNGNKASFFYIMG-----------ELGLSAHVADD 216
            |..:..:..|                 .|.|.|:   :.:..|           :.|::|....|
 Frog   152 YVFSQDLTMT-----------------DEMDGGD---WNFCEGRRRGHEQFGSCQQGVAATFTKD 196

  Fly   217 NTKFLIGAPGINTWRGSV-----------ILYRQVDPVDNPTASRRDTSKALRRTYRDVDSNDYT 270
            ....:.||||...|:|.|           :...:..|.:....::||:..
 Frog   197 FHYIVFGAPGTYNWKGVVRAEQKNNTLEDLFIFEDGPYETGGENKRDSDL--------------- 246

  Fly   271 PEHYAPEIPTPGLWGQEEDSYFGYAVSSGFFDSSNPTKLLYVATAPQANKQSGEAYI---FDVRG 332
                   :|.|      ::||.|:::.:|...:|. .::.:|:.||:|| .||...:   |....
 Frog   247 -------VPAP------DNSYLGFSLDTGRGITSK-EEMTFVSGAPRAN-HSGAVVLLQKFPPNE 296

  Fly   333 KSIHKYHVFRGEQFGEYFGYSVLAEDLNGDGKTDVIVSAPQHALEDSHD---NGAIYVFIN-KGF 393
            :.:...|.|:||.....|||.|...|||.||..|::|.|||:.  |.:|   .|||||:|| :|.
 Frog   297 RMLSAVHTFQGEGLASSFGYDVAVVDLNRDGWKDIVVGAPQYF--DKNDREIGGAIYVYINQQGN 359

  Fly   394 FNFERQILRSPVETM----ARFGTALSRLGDINHDGYNDVAVGAPF-AGNGTVFIYLGSENGLRD 453
            :|   .::  ||..:    :.||.::..:||||.|||.|:|||||: .|.|.|::|.||::|:..
 Frog   360 WN---DVM--PVRIVGTKDSMFGISVKNIGDINQDGYPDIAVGAPYDDGFGKVYVYHGSKDGIIS 419

  Fly   454 QPSQRLDAPSQQPSKYGSHMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKVHATVK 518
            :|:|.::..|.     .:..||:.::...|:|.|.:.|.|:|: .:::|.::|:.||:.:..|:|
 Frog   420 EPAQVIEGRST-----NTRFFGYSIAGDMDLDQNSYPDIAVGS-LSDSVKVFRSRPVITIKKTIK 478

  Fly   519 SESREI--------KPEQEKVKITACYR-----------LSTTSTDKLVQEQELAIRIAMDKQLK 564
            .....|        .|....:::..|:.           |:.:.|.:|..::.|     :.|.|
 Frog   479 VTPDRIDFNKKNCDAPSGICLEVEGCFEYTANPKTYNPVLTLSCTFELENDRRL-----LQKPL- 537

  Fly   565 RVKFTQ-TQTNEI--SFKVNANFGEQCRDFETQVRYSEKDIFTPIDLEMHYEL---TKKVPDSEE 623
            |:.|.. .|.:::  :.::......:|.....|:..|.:|...||.:.:..|:   .::...|..
 Frog   538 RMNFKDLPQESKLPKTIELRGQNQRRCVTTTLQLLESIRDKLHPIAVSVSAEIKSVRRRKRQSSP 602

  Fly   624 FCETCAIVDPTEPKVSTQNIIF-STGCATD-VCTADLQLRSKDVS-----------------PTY 669
            ..|...|::..|||.:|.|:.| ..||..| :|.:::||:.|.::                 |..
 Frog   603 LPELMPILNSNEPKNATANVQFLKEGCGEDNICNSNMQLKYKFLTREGSHDSFTELKQENGIPVL 667

  Fly   670 ILGSADTLRLNYEITN----------IGETAYLPQFNVTSTSRLAFAQVPGNCKVVDAVMVCDLN 724
            .|.:...:.|...:||          .|:.|:..|......|.|::::.......:|..::|..|
 Frog   668 ALKNQKEIALEVTVTNKPSNPANPKLDGDDAHEAQLTAELPSSLSYSKYVELNPQLDKPLICASN 732

  Fly   725 ---------RGRPLAKGDTDSVTISFDVSQLSGQSLIIHAEVFSTGYEQNPTDNRQTNVIGLKEF 780
                     .|.|..:....:..:....:::|              .:.|..|      |||...
 Frog   733 PNGSVVFCELGNPFKRNANVTFYLILSTNEIS--------------VDTNELD------IGLNLK 777

  Fly   781 TEIDASGGQTNSQIDLEHYSNSAEIVNNYEIKSNG---PSVI-------------EQLTVSFYIP 829
            |        |:||.:|...:..|.:|....:..:|   ||.:             .:..:...|.
 Frog   778 T--------TSSQANLAPVAAKARVVVELLLSVSGVAKPSQVYFGGNVLGESAMKSEDDIGNLID 834

  Fly   830 IAYKVAGSTAIIPIINVTSLKMQ---ASYDSQLLSIDLYDQNNTMLVVDPVEVTTTLSGGLERTV 891
            ..::|......:..:..|.|.:|   ..|:.:.|   ||             :....|.||::
 Frog   835 FDFRVTNFGRPLKALGTTFLNIQWPKEIYNGKWL---LY-------------LVKMESEGLDK-- 881

  Fly   892 ITQNRQSYDIHTSGHVHQTMEVLDTSMVATASMSRKRRDLKALTANREQYARISNVKAHDLLSDD 956
                   .:...:|.::: :::|:      :..:|.||::      .|..:..|: |:..|.|:
 Frog   882 -------MECQPAGEINK-LKLLE------SGKTRHRREI------GESQSGTSD-KSFSLFSE- 924

  Fly   957 FKGKLPVNRTIVFNCRDPEMTICVRAEMRVHFRPEKSINLNMRYSVDLNEV--------NAILVD 1013
                   .:.:..:|.:....:.::..:               :.:|.|.:        |:..::
 Frog   925 -------RKYMTLDCNNQAKCVTIKCPL---------------HGMDSNAIIKARSRLWNSTFLE 967

  Fly  1014 PW---EYFVILT-----------DLKLQKKGDPTSTSFSINRRIEPNIISKHQETGLPIWIIIVS 1064
            .:   .|..||.           ::||..:|      :.:...:.|. .:..|.:|:|.|||.|:
 Frog   968 EYSKMNYLDILVKVFISVDTAAQNIKLANEG------YQVRVTVFPE-KTVAQYSGVPWWIIFVA 1025

  Fly  1065 VIGGLLLLSAISYLLYKFGFFNRTKKDE 1092
            ::.|:|:|:.:.:||:|.|||.|::.|:
 Frog  1026 ILAGILMLALLVFLLWKCGFFKRSRYDD 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	17/60 (28%)
		FG-GAP	350..388	CDD:280083	20/40 (50%)
		Int_alpha	409..459	CDD:214549	24/50 (48%)
		Int_alpha	473..>515	CDD:214549	12/41 (29%)
		Integrin_alpha2	507..829	CDD:285619	70/400 (18%)
itga6	XP_002934665.3	Int_alpha	36..97	CDD:214549	17/60 (28%)
		Int_alpha	251..300	CDD:214549	13/50 (26%)
		Int_alpha	312..361	CDD:214549	24/50 (48%)
		Int_alpha	373..425	CDD:214549	24/51 (47%)
		Int_alpha	434..>457	CDD:214549	7/22 (32%)
		Integrin_alpha2	467..943	CDD:369878	93/556 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910