Protein Alignment scb and itga3

DIOPT Version :9

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: XP_004918665.2
• Gene: itga3 / 100494331
• XenbaseID: XB-GENE-493979
• Length: 1030
• Species: Xenopus tropicalis
• Alignment Length: 1208
• Identity: 279/1208 - (23%)
• Similarity: 484/1208 - (40%)
• Gaps: 306/1208 - (25%)

  Fly    13 LALLALISHIEAFNFMPRPSRVINSPKHLKFHINQ---TRSSYFGYTLVIRQTS-------IIVG 67
            |.||||:.         ||:...|  ...:|.:.:   .....||:::.:.:.|       ::.|
 Frog     9 LLLLALLC---------RPACAFN--LDTRFPVLKEAGVPGGLFGFSVSLHRQSEGEQRYLLLSG 62

  Fly    68 APRAQSTLESQRTINETGAIYRCSLTNGV--CSPYVLDSRGNVDAPYSEYTFDSERKDFQWLGGS 130
            ||  |.........|.|||:|.|.:|:..  |....:|...:   |.:...      :..|||.:
 Frog    63 AP--QDAAAPSVKANRTGALYACPITSSTNDCFRVPIDPESD---PQNNII------ENMWLGVT 116

  Fly   131 MDGGTKDTDKLLVCAPRF----YAPSSRDNHLHGVCYWVNNTVASTPQHVTRISPLRLKSEQVKE 191
            :.....| .::|||..|:    ::.......:.|.||                  :|..:.::.|
 Frog   117 VASQGPD-GRVLVCGHRYTSVRWSGEEDQRRMIGKCY------------------IRGNNLELNE 162

  Fly   192 EDNG--------NKASFFYIMG--ELGLSAHVADDNTKFLIGAPGINTWRGSVILYRQVDPVDNP 246
            :|:.        :..|.|...|  ::|:|.....:...|  ||||..||:||..:.
 Frog   163 DDDWQTYHNELCDPNSDFDATGMCQMGISGGFTSNMVYF--GAPGAYTWQGSNFIL--------- 216

  Fly   247 TASRRDTSKALRRTYRDVDSNDYTPEHYAPEIPTPGLWGQEEDSYFGYAVSSGFFDSSNPTKLLY 311
               :|||:..|:..|                .||...:    :.|.||.|...       :::|:
 Frog   217 ---QRDTAWDLKEIY----------------YPTNNTF----NIYMGYTVQVN-------SRVLH 251

  Fly   312 ------VATAPQANKQSGEAYIFDVRGKSIHKYHVFRGEQFGEYFGYSVLAEDLNGDGKTDVIVS 370
                  |::||:. :..|..::.||:...:...||..|:|.|.|||.::...|||.||..|::|.
 Frog   252 KDQVTVVSSAPRW-ESKGAVFLLDVQKNIMVVKHVLNGQQVGSYFGSAIALADLNNDGWQDIVVG 315

  Fly   371 APQHALEDSHDNGAIYVFIN-KGFFNFERQILRSPVETMARFGTALSRLGDINHDGYNDVAVGAP 434
            ||.:........||:||:.| .|||| ::..:.....:.:.||.||:.:||||.||:.|:|||||
 Frog   316 APYYFDRKEEIGGAVYVYNNVAGFFN-DKAAMVLHGSSFSGFGFALANIGDINQDGFTDLAVGAP 379

  Fly   435 FAGNGTVFIYLGSENGLRDQPSQRLDAPSQQPSKYGSHM-----FGHGLSRGSDIDGNGFNDFAI 494
            |.|.|.|:||..:.:|.:.:|||.:|         ||.:     ||:.||.|.|:|.|.:.|..:
 Frog   380 FDGLGKVYIYNSNADGPKQEPSQVID---------GSQVANISTFGYSLSGGLDVDDNAYPDLLV 435

  Fly   495 GAPNAEAVYLYRAYPVVKVHATVKSESREIKPEQ----EKVKITACYRLSTTSTDKLVQEQELAI 555
            |: ..:.:.|.|:.||:.:....|.....:.|.:    ..:.:..|:.. |.||......:.:.:
 Frog   436 GS-LTDRIALLRSRPVINISKDFKVTPTLVDPSKCSNTSCIDVLVCFSY-TLSTGNAAYRKNITL 498

  Fly   556 RIAM----DKQLKRVKFTQTQTNEISFKVNANFGEQCRDFETQVRYSEKDIFTPIDLEMHYELTK 616
            :..:    |::..|||| |..:..:...:.:....:|::.:..:..:.:|...||.:.:.|.:.:
 Frog   499 QYTLEADHDRRPPRVKF-QGASGAVYQGLFSMPDTKCQNVQLLLLDNIRDKLHPISISLKYSILE 562

  Fly   617 K-------VPDSEEFCETCAIVDPTEPKVSTQNIIFSTGCATD-VCTADLQLRSKDVSPTYILGS 673
            :       |...:.|    .::...:.......|.|...|.:| ||.::||::.:     |::|:
 Frog   563 REARGRSAVRSLDNF----PVLSEDQSNFQELEIHFQKECGSDNVCRSNLQMQYE-----YVVGN 618

  Fly   674 A-----------------DTLRLNYEITNI------GETAYLPQFNVTSTSRLAFAQV--PGNCK 713
            |                 :.:.||..:||.      .:.|:....|:|....|.|:.|  |..|.
 Frog   619 APLSKVNGSQILHYDSSVNKVNLNVIVTNFPSATSPADDAHEAVLNITIPPELFFSSVRPPLACT 683

  Fly   714 VVDAVMVCDLNRGRPLAKGDTDSVTISFDVSQLSGQSLIIHAEVFSTGYEQNPTDNRQTNVIGLK 778
            :.:.: :|:|  |.|..:.....:||.|:|..:|.::    .||                |.||:
 Frog   684 LKETI-ICEL--GFPFKRNQKAEITIVFEVVGISLKT----REV----------------VAGLQ 725

  Fly   779 EFTEIDASGGQTNSQIDL-EHYSNSAEIVNNYEIK---SNGPSVIEQLTVSFYIPIAYKVAGSTA 839
            ..|        .:.|.|| |.|   |:::.:|.:|   |..||.|:..       .:..|.|.:|
 Frog   726 LST--------LSKQDDLHEEY---AKLLVDYTLKISFSVQPSHIQTY-------FSGNVMGESA 772

  Fly   840 IIPIINVTSLKMQAS-----YDSQLLSIDL--------YDQNNTMLVVDPVEVTTTLSGGLERTV 891
            :..:.:|.| .::.|     |...|.|:..        ::..|...::.|.||  .::.|.|:.
 Frog   773 MKTVQDVGS-PVEFSFTVINYGEPLTSLATLFIAFNWPHEVANGKWLLYPTEV--LVNTGTEKA- 833

  Fly   892 ITQNRQSYDIHTSGHVHQTMEVLDTSMVATASMSRKRR------DLKALTANREQYARISNVKAH 950
                     .|.||.|...:.:    .|:...:.|:||      |::.|.|.|.:       .:.
 Frog   834 ---------CHPSGDVINPLNL----NVSETLVKRRRRQIDETPDVRTLAAVRRE-------SSE 878

  Fly   951 DLLSDDFKGKLPVNRTIVFNCRDPEMTICVRAEMRVHFRPEKSINLNMRYSVDLNEVNAILVDPW 1015
            .:|.....|...|:.:...|......||.:|..:           .|..:..|...|:.:.|...
 Frog   879 AVLKCSGGGATCVHFSCPLNDMQSRATISMRGRV-----------WNSTFLEDYRNVDRVWVMGG 932

  Fly  1016 EYFVILTDL-KLQKKGDPTSTSFSINRRIEPNIISKHQETGLPIWIIIVSVIGGLLLLSAISYLL 1079
            ....:.||: .:..|....:.|.||:..:|     :.....||:|:|||||:.|::||..|..||
 Frog   933 AELYLKTDVPTINMKSQFVTFSVSIDSELE-----EPPPAELPLWLIIVSVVSGIVLLGIIILLL 992

  Fly  1080 YKFGFFNR-----------------TKKDELDRLVQQN 1100
            :|.|||.|                 .:..|.:||.|.|
 Frog   993 WKCGFFRRANTRAMYEVRGQKAEMKVQPSETERLTQDN 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	15/60 (25%)
		FG-GAP	350..388	CDD:280083	14/37 (38%)
		Int_alpha	409..459	CDD:214549	26/49 (53%)
		Int_alpha	473..>515	CDD:214549	14/46 (30%)
		Integrin_alpha2	507..829	CDD:285619	71/366 (19%)
itga3	XP_004918665.2	Int_alpha	37..98	CDD:214549	15/62 (24%)
		Int_alpha	292..>335	CDD:214549	17/42 (40%)
		Int_alpha	352..404	CDD:214549	26/51 (51%)
		Int_alpha	415..>437	CDD:214549	9/21 (43%)
		Integrin_alpha2	447..895	CDD:369878	101/523 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910