Protein Alignment scb and itga1

DIOPT Version :9

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: XP_002933090.3
• Gene: itga1 / 100492880
• XenbaseID: XB-GENE-6258629
• Length: 1173
• Species: Xenopus tropicalis
• Alignment Length: 1175
• Identity: 267/1175 - (22%)
• Similarity: 435/1175 - (37%)
• Gaps: 311/1175 - (26%)

  Fly    39 KHLKFHINQTRSSYFGY---------------TLVIRQTSIIV---GAPRAQSTLESQRTINETG 85
            |::..:.|||:.....|               |..:||.|:.:   |..:..:.|.......|..
 Frog   190 KNMNINPNQTQVGIVQYGENVTHEFNLNTYDSTAKVRQASLGIKQRGGSQTMTALGIDTARKEAF 254

  Fly    86 AIYRCSLTNGVCSPYVLDSRGNVDAPYSEYTFDS-----ERKDFQWLG----GSMDGGTKDTDKL 141
            ...| ....||....|:.:.|.   .:..|..:|     |..|.|...    ||.:.|...|: .
 Frog   255 TEAR-GARKGVKKVMVVVTDGE---SHDNYRLNSVIKECETDDIQRFSIAILGSYNRGNLSTE-T 314

  Fly   142 LVCAPRFYAPSSRDNHLHGVC--YWVNNTVASTPQHVTRISPLRLKSEQVKEEDNGNKASFFYI- 203
            ||...:..|...::.|...|.  ..:.|.|.|..:.:..:           |..|..:||.|.:
 Frog   315 LVEEIKSIASEPKEKHFFNVSDELALLNIVESLGERIFAL-----------EATNEERASSFQME 368

  Fly   204 MGELGLSAHVADDNTKFLIGAPGINTWRGSVILYRQVDPVDNPTASRRDTSKALRRTYRDVDSND 268
            |.:.|||||.:.|..  ::||.|...|.|:|::.       |..|:....::..|:.
 Frog   369 MSQTGLSAHYSKDWA--MLGAVGAYDWNGTVVMV-------NSDATLIPNNQTFRKR-------- 416

  Fly   269 YTPEHYAPEIPTPGLWGQEEDSYFGYAVSSGFFDSSNPTKLLYVATAPQANKQSGEAYIFDVRGK 333
             |.|...|..           :|.||.:||    :|...:.:|:|..|:.| .||:..|:.:.|:
 Frog   417 -TDEKNEPLA-----------AYLGYTLSS----ASVHGEEIYIAGQPRYN-HSGQVIIYKLNGE 464

  Fly   334 SIHKYHVFRGEQFGEYFGYSVLAEDLNGDGKTDV-IVSAPQHALEDSHDNGAIYVFINKGFFNFE 397
            .|.......|||.|.|||..:...|::||..:|: ||.||.:......:.|.:||:...| ....
 Frog   465 EIEVLQTLNGEQIGSYFGSVLTTVDVDGDSISDILIVGAPMYMGSAKQEQGKVYVYRIHG-KEMH 528

  Fly   398 RQILRSPVETM--------------------ARFGTALSRLGDINHDGYNDVAVGAPFAGN--GT 440
            .|:...|:...                    :|||||::.:.|:|.||:||||:|||..|:  |.
 Frog   529 YQMSLEPLNQTCCSQQKDISCQNENQNEPCGSRFGTAIAAVTDLNLDGFNDVAIGAPLEGDHRGA 593

  Fly   441 VFIYLGSENGLRDQPSQRLDAPSQQPSKYGSHMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLY 505
            |:||.||...:::..:||:  ||....| ....||..:....|::|:|..|..||.....:::..
 Frog   594 VYIYHGSGKSIKENYAQRI--PSGGDGK-KVRFFGQSIHGEMDLNGDGLTDVTIGGLGGASLFWS 655

  Fly   506 RAYPVVKVHATVKSESREIKPEQEK----------VKITACYRLSTTSTDKLVQEQELAIRIAMD 560
            |  .|.::..|.:.....|..|::.          :|...|:.|...|.:......::...|.:|
 Frog   656 R--DVAEITVTTEFTPNAINIEKKDCTVSNRPTVCIKARFCFNLLLKSGEDKKASSDIIYTITLD 718

  Fly   561 --KQLKRVKFTQTQTNEISFKVNANFGEQ--C--RDFETQVRYSEKDIFTPIDLEMHYELTKKVP 619
              :...||.|..:|..    |.....|.:  |  .||.|   ..:.|....|::.:.:..    |
 Frog   719 SPRYASRVLFNDSQDR----KFQGVMGHKGNCLNHDFYT---VEKPDFLNSINVSVEFNF----P 772

  Fly   620 DSEEFCETCAIVDPTEPKVSTQNIIFSTGCATD-VCTADLQLR---SKD--------VSPTYILG 672
            |.|:    ..::....|......|.|:..|.:: .|..||.|.   |.|        |.||
 Frog   773 DPEK----GPVLSSELPNFYNSYIPFTMDCGSEQKCITDLVLDAEISMDGISFNEAIVKPT---- 829

  Fly   673 SADTLRLNYEITNIGETAYLPQFNVTSTSRLAFAQVPGNCKV---VDAVMVCDLNRGRPLAKGDT 734
             .|...|...:.|:.::||..:..|..:..:..|......||   .|..:.|.:  |.|..|.|.
 Frog   830 -KDKFNLTLTVKNMKKSAYNARVIVKYSPNIILAATEDKQKVSCESDHDVTCKI--GYPFLKKDE 891

  Fly   735 DSVTISFDVS-QLSGQSLIIHAEVF---STGYEQNP---TDNRQ------------TNVIGLKEF 780
               .|||.:: |.:...|:.:..:|   ::..|:.|   .:||:            |.|...|||
 Frog   892 ---MISFKITFQFNSSHLLDNTFIFVNATSDSEEKPETLMNNRKNITFTVKYESWLTFVSSTKEF 953

  Fly   781 TEIDASGGQTNSQIDLEHYSNSAEIVN-----NYEIKSNGPSVIEQLTVSFYIPIAYKVAGSTAI 840
            ....|:.....:.|      ||.|.:.     :|.|:.|  ..|....|||.:...||...:..:
 Frog   954 HVPIAANDSIPATI------NSTEAIGAEVNIHYVIRKN--DFIPMPKVSFRLSFPYKTPDNNIL 1010

  Fly   841 IPIINVTSLKMQASYDSQLLSIDLYDQNNTMLVVDPVEVTTTLSGGLERTVITQNRQSYDIHTSG 905
            :.:.|| |.....:..|.||              ||:.:                       .||
 Frog  1011 LYLTNV-SFSHNVNCSSDLL--------------DPLSI-----------------------NSG 1037

  Fly   906 HVHQTMEVLDTSMVATASMSRKRRDLKALTANREQYARISNVKAHDLLSDDFKGKLPVNRTIVFN 970
            ..: ||                                           .:||..|   |..:.:
 Frog  1038 KTY-TM-------------------------------------------PEFKENL---RDTILD 1055

  Fly   971 CRDPEMTICVRAEMRVHFRPEKSINLNMR------YSVDLNEVNAILVDPWEYFVILTDLKLQKK 1029
            |:..:   |...|..|....:..||:::|      ...:::.:|.:|           :.|||.:
 Frog  1056 CKRSK---CSSFECTVEPANDTHINVSLRVWKSTFIKANIHNLNLVL-----------NAKLQSE 1106

  Fly  1030 GDPTSTSFSIN---RRIEPNI-ISKHQETG-LPIWIIIVSVIGGLLLLSAISYLLYKFGFFNRTK 1089
                |:...:|   |..|..| |||..|.| :|.|:|.:|:|.|||:|:.|.:.::|.|||.|..
 Frog  1107 ----SSLLVLNPGSRNYETMIKISKELEHGKVPFWVIPLSIIIGLLILALIIFAMWKTGFFKRPL 1167

  Fly  1090 KDELD 1094
            |::::
 Frog  1168 KEKME 1172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	12/69 (17%)
		FG-GAP	350..388	CDD:280083	12/38 (32%)
		Int_alpha	409..459	CDD:214549	24/51 (47%)
		Int_alpha	473..>515	CDD:214549	10/41 (24%)
		Integrin_alpha2	507..829	CDD:285619	80/376 (21%)
itga1	XP_002933090.3	vWFA	163..343	CDD:412136	31/157 (20%)
		Int_alpha	477..>524	CDD:214549	15/46 (33%)
		Int_alpha	559..612	CDD:214549	24/52 (46%)
		Integrin_alpha2	655..1066	CDD:400650	101/533 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010