Protein Alignment scb and itga11

DIOPT Version :9

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: XP_017947982.1
• Gene: itga11 / 100489152
• XenbaseID: XB-GENE-483822
• Length: 1188
• Species: Xenopus tropicalis
• Alignment Length: 1403
• Identity: 297/1403 - (21%)
• Similarity: 474/1403 - (33%)
• Gaps: 538/1403 - (38%)

  Fly    14 ALLALISHIEAFNFMPRPSRVINSPKHLKFHINQTRSSYFGYTLVIRQTS----IIVGAPRAQST 74
            ||..|....:.||...:..|:|:..|          .::||||:...|.:    ::||||
 Frog    12 ALCLLPGLTDTFNIDTKRPRIISGSK----------DAFFGYTVQQHQIAGKKWLVVGAP----- 61

  Fly    75 LESQRTIN---ETGAIYRCSLTN---------GV------------------------------- 96
                ..:|   :||.||:||:||         |:
 Frog    62 ----FDVNGPQKTGDIYKCSVTNDTSNDCTKLGIGRVTLSNVSERKDNMRLGMSLVTNPKDNSFV 122

  Fly    97 -CSP----------YV--LDSRGNVDAPYSEY---------TF-------DSERKDFQWL----- 127
             |||          |.  :.||.|.:..:|..         ||       |.....:.|:
 Frog   123 ACSPLWSHECGSSYYTTGMCSRVNSNFRFSRIVAPALQRCPTFMDIVIVLDGSNSIYPWVEVQSF 187

  Fly   128 ---------------------------------------------------GGS----------- 130
                                                               ||:
 Frog   188 LISILQKFYIAPGQIQVGVLQYGETVVHEFYLNNYRSVTDVVEAAKRIEQRGGTETRTALGIEKA 252

  Fly   131 -----MDGGTKDTDKLLVC--------AP---RFYAPSSRDN---------------------HL 158
                 ..||.|...|:::.        :|   |....|.:||                     .|
 Frog   253 VTEAFQRGGRKGAKKVMIVITDGESHDSPDLQRVIESSEKDNITRYAVAVLGYYNRRGINPEAFL 317

  Fly   159 HGVCYWVNNTVASTPQ-----HVTRISPLRLKSEQVKEE-------DNGNKASFFYIMGELGLSA 211
            :.:.|     :||.|.     :||..:.|:...:.:.|.       .|.|:.||...|.:.|.|:
 Frog   318 NEIKY-----IASDPDDKHFFNVTDEAALKDIVDALGERIFSLEGGTNKNETSFGLEMSQAGFSS 377

  Fly   212 HVADDNTKFLIGAPGINTWRGSVILYRQVDPVDNPTASRRDTS--KALRRTYRDVDSNDYTPEHY 274
            ||.:|.  .|:||.|...|.|:|:               ::||  |.:.|.           |.|
 Frog   378 HVVEDG--ILLGAVGAYDWNGAVL---------------KETSSGKVIPRR-----------ESY 414

  Fly   275 APEIPTPGLWGQEEDSYFGYAVSSGFFDSSNPTKLLYVATAPQANKQSGEAYIFDVRG---KSIH 336
            ..|.|..   .:...:|.||.|:|..   :.....:|||.||:.| .:|:..:|.:.|   .:||
 Frog   415 LKEFPDE---LKNHGAYLGYTVTSVM---TWQRVRIYVAGAPRFN-HTGKVIVFTMHGAENMTIH 472

  Fly   337 KYHVFRGEQFGEYFGYSVLAEDLNGDGKTDV-IVSAPQHALEDSHDNGAIYVFINKGFFNFERQI 400
            :  ..:|.|.|.|||..:.:.|::|||.||: :|.||.:.: |..:.|.:.||:.:     |||.
 Frog   473 Q--ALQGNQIGSYFGGEMDSVDVDGDGVTDILLVGAPMYFI-DGWERGRVSVFVLR-----ERQF 529

  Fly   401 LRSPV------ETMARFGTALSRLGDINHDGYNDVAVGAPFAGN--GTVFIYLGSENGLRDQPSQ 457
            :.:..      ...:|||::::.:.|:|.|.||||.||||...|  |.::|:.|....:..:..|
 Frog   530 IHNGFLQDLNSSQNSRFGSSIAAVPDLNQDLYNDVVVGAPLEDNHKGAIYIFHGLRKNILKKYKQ 594

  Fly   458 RLDAPSQQPSKYGSHMFGHGLSRGSDIDGNGFNDFAIGAPNAEAVYLYRAYPVVKVHATVKSESR 522
            |:.|....|   |...||..:....|::.:|..|.|:|: ...||.|: ...|||::||:..|
 Frog   595 RISAAELAP---GLVYFGCNIHGEMDMNEDGLVDLAVGS-MGNAVLLW-TRSVVKINATMHFE-- 652

  Fly   523 EIKPEQEKVKITACYRLSTTSTDKLVQEQELAIRIAMDKQLKRVKFTQTQTNEISFKVNANFGE- 586
               |.:..:....|:|....:|.       ::..|......|..:|   |...::.|.|.:..|
 Frog   653 ---PPKINIFSKDCHRNGREATC-------MSAFICFSPMFKAQQF---QGQNVAIKYNVSIDER 704

  Fly   587 ----------------------------QCRDFETQVRYSEKDIFTPIDLEMHYELTKKVPDSEE 623
                                        ||:.....| ....|...||...:.|||.
 Frog   705 RYIPRAIIDDIGGDKHFVKTIRATSGHNQCQQLNFHV-LDTADYVKPITFSLEYELA-------- 760

  Fly   624 FCETCAIVD---PTEPKVSTQNIIFSTGCATDV-CTADLQLRSKDVSPT---------YILGSAD 675
            |.:...:::   ||..|||   :.|..||..|. |..||.|..|...||         |...||.
 Frog   761 FSDQGPVLEEDWPTSLKVS---VPFWNGCNQDERCVPDLYLDVKHDIPTALEYCQRFLYRTQSAC 822

  Fly   676 T-------------------LRLNYEITNIGETAYLPQFNVTSTSRLAFA--------QVPGNCK 713
            |                   :.|...:.|.||.||....|::.:..|.||        .:...||
 Frog   823 TEFISAFDNSVFIIQRSRRRVALEVVLENRGENAYSTALNISHSQNLQFASLITKEDSDIKIECK 887

  Fly   714 VVDA---VMVCDLNRGRPLAKGDTDSVTISFDVSQLSGQSLIIHAEVFSTGYEQNPTDNRQTNVI 775
            ..|.   ...|:::.....||... :..:.|:.|:                |:..|
 Frog   888 SDDRFPHTKTCNVSYPFFRAKAKV-AFRLDFEFSK----------------YQFLP--------- 926

  Fly   776 GLKEFTEIDASGGQTNSQIDLEHYSNSAEIVNNYEIKSNGPSVIEQLTVSFYIPIAYKVAGSTAI 840
                |.::..|.|..:.:.:...:.|  |::.::.:|
 Frog   927 ----FLQVHLSAGSDSEEQESTRFDN--EVLLDFHLK---------------------------- 957

  Fly   841 IPIINVTSLKMQASYDSQLLSIDLYDQNNTMLVVDPVEVTTTLSGGLERTVITQNRQSYDIHTSG 905
                          |:|.|    |:.:::::   :..|:|:..|......:......|:.|...|
 Frog   958 --------------YESDL----LFTRHSSL---NHYEITSEGSADRYNAIGPPFNSSFKIQNLG 1001

  Fly   906 HVHQTMEVLDTSMVATASMSRKRRDLKALTANREQYARISNVKAHDLLSDDFKGKLPVNRTIVFN 970
            ...:.:.:..|..|||...:| ...|.:|.:::|.  .:.|:..:   |.|::.| |....:
 Frog  1002 FFPEEINLKITVPVATRGGNR-LLFLHSLISDQEN--AVCNIWGN---STDYRRK-PTEEDL--- 1056

  Fly   971 CRDPEMTICVRAEMRVHFRPEKSINLNMRYSVDLNEVNAILV--DPWEYFVILTDLKLQKKGDPT 1033
            .|.|:                    ||...| |:..::.:|:  ...|...||       .||..
 Frog  1057 SRVPQ--------------------LNHSNS-DVISIDCVLILASNQEASFIL-------HGDLW 1093

  Fly  1034 STSF------SIN-----------------RRIEPN-----IISKHQETGLPIWIIIVSVIGGLL 1070
            |.||      |:|                 |..||.     .|||.:|..:|||:||.|.:||||
 Frog  1094 SRSFRAMNFRSVNVVVFAALQRKFQSPFIFREEEPTRQITFAISKQEEWEVPIWVIITSTLGGLL 1158

  Fly  1071 LLSAISYLLYKFGFFNRTKKDELDRLVQQNPVEPEAEN 1108
            ||:.:...|:|.|||.|:..            |.|.||
 Frog  1159 LLALLVLALWKLGFFKRSHH------------EREEEN 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	23/111 (21%)
		FG-GAP	350..388	CDD:280083	13/38 (34%)
		Int_alpha	409..459	CDD:214549	19/51 (37%)
		Int_alpha	473..>515	CDD:214549	13/41 (32%)
		Integrin_alpha2	507..829	CDD:285619	73/393 (19%)
itga11	XP_017947982.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010