Protein Alignment scb and itgae.1

DIOPT Version :9

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: XP_002664631.3
• Gene: itgae.1 / 100333951
• ZFINID: ZDB-GENE-131121-125
• Length: 547
• Species: Danio rerio
• Alignment Length: 593
• Identity: 95/593 - (16%)
• Similarity: 176/593 - (29%)
• Gaps: 205/593 - (34%)

  Fly    13 LALLALISHIEAFNFMPRPSRVINSPKHLKFHINQTRSSYFGYTLVIRQTSIIVGAPRAQSTLES 77
            |..:.::.:...||..      |:..||.     ......||.|::..:..|.|.:|
Zfish     5 LLFVMVLCNAAGFNIQ------ISPVKHF-----TNEDPLFGQTIIQAKDGIFVPSP-------- 50

  Fly    78 QRTINETGAIYRCSLTNGVCSPYVLDSRGNVDAPYSEYTFDSERKDFQWLGGSMDGGTKDTDKLL 142
                 ..|.:::|:|.|......:.|.......|.:                |:...|.....::
Zfish    51 -----TYGRLFKCTLDNECTKVNINDENPKGMRPVA----------------SVASLTSQEQHVV 94

  Fly   143 VCAPRFYAPSSRDNHLHGVCYWVNNTVASTPQHVTRISPLRLKSEQVKEEDNGNKASFFY----- 202
            :| .:....:....:|:|:|..|      :|....::.|..|.:.:....:|.|..:.:.
Zfish    95 MC-NQVRTENRGTEYLNGICTLV------SPSGKVKLYPAELDNNKNNNNNNNNNNNKYQGGRIN 152

  Fly   203 ------IMGELGLSAHVADDN---TKFLIGAPGINTWR--------------------------- 231
                  |...|..|..:.||:   .|..|.....|.|:
Zfish   153 QGPGTEIAFVLDGSGSIQDDDFQKAKDFIYNVMSNVWKTCFDCNFAIVQYGSLIRTELSLLDNED 217

  Fly   232 --GSVILYRQVDPVDNPTASRRDTSKALRRTYRDVDSNDYTPEHYAPEIPTPGLWGQEEDSYFGY 294
              ||::..:|:..:.|.|    .|:.|:.....|:    :.||:           |.:::|....
Zfish   218 RVGSLLKVKQIKQIYNLT----KTASAINHVLTDI----FIPEN-----------GSKDNSAKII 263

  Fly   295 AVSSGFFDSSNPTKLLYVATAPQANKQSGEAYIFDVRGKSIHKYHVFRGEQF------------- 346
            .|.|......:|..|..|...||.              |.:.:|.:..|:..
Zfish   264 IVLSDGKILGDPMTLDEVLNKPQM--------------KGVTRYSIGVGDGILKNLDATEEMMQI 314

  Fly   347 ---GEYFGYSVLAEDLNGDGKTDVIVSAPQHALEDSHDNGAIYVFINKG---------------F 393
               |:|:..|.. ..||.      |||:.:..:..:.|.|....|:..|               .
Zfish   315 ADPGKYYNVSSY-RALND------IVSSLERGIIGTKDPGTEIAFVLDGSGSIQDDDFQKAKDFI 372

  Fly   394 FNFERQILRSPVE---TMARFGTAL----------SRLGD-------------------INHDGY 426
            :|....:.::..:   .:.::|:.:          .|.|.                   ||| ..
Zfish   373 YNVMSNVWKTCFDCNFAIVQYGSLIRTELLLLDNEDRAGSLLKVKQIKQIYNLTKTASAINH-VL 436

  Fly   427 NDVAVGAPFAGNGTVFIYLGSENGLRDQPSQRLDAPSQQPSKYGSHMFGHGLSRGSDIDGNGFND 491
            .|:.:....:.|.|..|.:...:|...:....||....:|...|...:..|:       |:|.
Zfish   437 TDIFIPEKGSKNNTAKIIIVLSDGEILEDPMTLDEVLNKPQMKGVTRYSIGV-------GDGI-- 492

  Fly   492 FAIGAPNA 499
              :..|||
Zfish   493 --LKKPNA 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	10/51 (20%)
		FG-GAP	350..388	CDD:280083	8/37 (22%)
		Int_alpha	409..459	CDD:214549	11/78 (14%)
		Int_alpha	473..>515	CDD:214549	6/27 (22%)
		Integrin_alpha2	507..829	CDD:285619
itgae.1	XP_002664631.3	vWFA	157..332	CDD:294047	36/214 (17%)
		vWFA	348..523	CDD:294047	24/163 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740