Protein Alignment scb and itga3b

DIOPT Version :10

• Sequence 1: NP_523750.2
• Gene: scb / 36692
• FlyBaseID: FBgn0286785
• Length: 1115
• Species: Drosophila melanogaster
• Sequence 2: NP_001177238.1
• Gene: itga3b / 100331874
• ZFINID: ZDB-GENE-050411-55
• Length: 1041
• Species: Danio rerio
• Alignment Length: 1205
• Identity: 295/1205 - (24%)
• Similarity: 502/1205 - (41%)
• Gaps: 279/1205 - (23%)

  Fly    10 HIFLALLALISHIEAFNFMPRPSRVINSPKHLKFHI---NQTRSSYFGYTLVI-RQTS------I 64
            |:.:.::..|.....||.            .::|.:   .:|:.|.||:::.: :||.      :
Zfish     7 HLCVFVICAIQTNTGFNI------------DVQFPVIKEGKTKGSLFGFSVALHKQTEKAKKNLL 59

  Fly    65 IVGAP--RAQSTLESQRTINETGAIYRCSLTNGVCSPYVLDSRGNVD---APYSEYTFDSERKDF 124
            :||||  :||..| |:..||||||:|.|.:|..      ||..|::|   .|.|     ::..:.
Zfish    60 LVGAPQEKAQPQL-SKFKINETGAVYYCPITVN------LDDCGSMDLISPPKS-----TDMLEG 112

  Fly   125 QWLG----GSMDGGTKDTDKLLVCAPRFYAP---SSRDNHLHGVCYWVNNTVASTPQHVTRISPL 182
            .|||    ...:||     ::|.|..|:...   :.....:.|.||...|.::..|....:....
Zfish   113 MWLGVTVASQRNGG-----RVLACGHRYVKKLLGAEEQQRMVGKCYVRGNDLSYDPSDYWQSETY 172

  Fly   183 RLKSEQVKEEDNGNKASFFYIMGELGLSAHVADDNTKFLIGAPGINTWRGSVILYRQVDPVDNPT 247
            .|......::..|        |..:|:|..:.:.:..|  |.||..||:|:|
Zfish   173 ELCDFNHDQDLEG--------MCNMGISGGMTEKDVYF--GTPGSFTWQGTV------------- 214

  Fly   248 ASRRDTSKALRRTYRDVDSNDYTPEHYAPEIPTPGLWGQEE-DSYFGYAVSSGFFDSSNPTKLL- 310
                      ....||.|| ||..:......   |..|::: :.|.||:|....       |||
Zfish   215 ----------HMKCRDTDS-DYAGDANDRSF---GKLGEDKFNIYIGYSVLEDI-------KLLD 258

  Fly   311 -----YVATAPQANKQSGEAYIFDVRGKSIHKYHVFRGEQFGEYFGYSVLAEDLNGDGKTDVIVS 370
                 .|..||: ::..|...:.|.:...:.:.....|||.|.|||..:...|||.|...|:||.
Zfish   259 RSVFTVVMGAPR-DEFKGSVILADKQDLILKQLMNITGEQIGSYFGSCLAVTDLNNDDWNDLIVG 322

  Fly   371 APQHALEDSHDNGAIYVFINKGFFNFERQ---ILRSPVETMARFGTALSRLGDINHDGYNDVAVG 432
            ||.:......:.||:|:|:|:. .:|:::   :|:.  :..:.||.|::.:||:|.||:.|:|||
Zfish   323 APFYFDRYKEEGGAVYIFMNEN-GSFQKKASLVLKG--KKGSGFGFAIAAVGDVNQDGFQDIAVG 384

  Fly   433 APFAGNGTVFIYLGSENGLRDQPSQRLDAPSQQPSKYGSHMFGHGLSRGSDIDGNGFNDFAIGAP 497
            |||..:|.|:|::||::|:..:|||.::..|..||  |...||:.||.|.|:|||.:.|..:|:.
Zfish   385 APFQDSGKVYIWMGSKSGITKEPSQVIEGKSLGPS--GFQTFGYSLSGGMDMDGNDYPDILVGSL 447

  Fly   498 NAEAVYLYRAYPVVKVHATVKSESREIKPEQ-----EKVKITACYRLSTTSTDKLVQEQELAIRI 557
            : :.:.|.|:.||:.:......|.:.:.|.|     .|||:...|.||..:::   ..:|:.::.
Zfish   448 D-DRIALLRSRPVIHLSKNFTVEPKIVIPSQCGNSCIKVKVCFSYTLSNGNSN---FRKEITVKF 508

  Fly   558 AMD----KQLKRVKF----TQTQTNEISFKVNANFGEQCRDFETQVRYSEKDIFTPIDLEMHYEL 614
            .:|    ::..||:|    ..|.|..:||..::     |::.|..|.....|...||...::..|
Zfish   509 TIDADQNRRGARVRFIDNKQSTFTGLLSFSASS-----CQELELSVNNPVTDKLQPIVFSLNVSL 568

  Fly   615 TKKVPDSEEFCETCAIVDPTEPKVSTQNII-------FSTGCATD-VCTADLQLRSKDVSPTYIL 671
            .::..:::   :|...:| :.|.:|.|.|:       |...|..| .|:::|||:::.....|..
Zfish   569 NQQKAEAQ---QTLQSLD-SFPVLSGQQILTDKAEINFHKECGDDNRCSSNLQLKARFADENYNP 629

  Fly   672 GSADTLR---------LNYEITNI------GETAYLPQFNVTSTSRLAFAQV--PG----NCKVV 715
            ..:.||.         |..|::|.      .|.|:....|::....|.::.|  |.    .|...
Zfish   630 FPSQTLEFSSNVKKLVLMVEVSNTADENKPAEDAHQATLNISIPYSLKYSGVRPPAGFDMECSAD 694

  Fly   716 DAVMVCDLNRGRPLAKGDTDSVTISFDV-----------SQLSGQSLIIHAEVFSTGYEQNPTDN 769
            :|| :|||  |.|.......|..|.|:.           |||...::...|::|......|..:.
Zfish   695 EAV-ICDL--GNPFKSNQKVSFIIIFETSGITLYTEQIQSQLQLSTISEQADLFPVLVTLNVKNT 756

  Fly   770 RQTNVIGLKEFTEIDASG---GQT--NSQIDLEHYSNSAEIVNNYEIKSNGPSVIEQLTVSFYIP 829
            ..|.....|...:...||   |::  :|..|:   .:..|.|...::.......:..|.:.|..|
Zfish   757 ILTTFSLEKLIIDTSFSGNVIGESAMSSTSDV---GSPLEFVFRVQVLGEPLGDLGTLVIDFDWP 818

  Fly   830 IAYKVAGSTAIIPIINVTSLKMQASYDSQLLSIDLYDQNNTMLVVDPVEVTTTLSGGLERTVITQ 894
              |.||....   ::.:|.:.::.|.:|.              .|.|..:...|:..|.:....:
Zfish   819 --YAVANGKW---LLYLTEIVIKGSSESH--------------CVPPGNIVNYLNLTLSKEGTKR 864

  Fly   895 NRQSYDIHTSG--HVHQTMEVLDTSMVATASMSRKRRDLKALTANREQYARISNVKAHDLLSDDF 957
            |::..|   ||  |...::.||.|..|                             ||.|   |.
Zfish   865 NKREVD---SGFPHAEASVTVLATRKV-----------------------------AHFL---DC 894

  Fly   958 KGKLPVNRTIVFNCRDPEMTICVRAEMRVHFRP---------EKSINLNMRYSVDLNEVNAILVD 1013
            ..|..:.:|  |:|  |.:.:..:||:||..|.         .|::.:.::....|.
Zfish   895 SKKTALCQT--FSC--PLLNMSTQAEVRVRARVWNGTLLEDYAKALRVEVKGQATLR-------- 947

  Fly  1014 PWEYFVILTDLKLQKKGDPTSTSFSINRRIEPNIISKHQETGLPIWIIIVSVIGGLLLLSAISYL 1078
                  :||| |...|.|..:..||:|  |:| ::.:.....:|:|||||:.:.|:|||..||.:
Zfish   948 ------LLTD-KPAIKMDNQTREFSVN--IDP-VLGEETPYEVPLWIIIVAAVAGILLLGIISLI 1002

  Fly  1079 LYKFGFFNRTKKDELDRLVQQN---PVEP-EAENL 1109
            |:|.|||.|..:.|:.....|.   .::| |.|.|
Zfish  1003 LWKCGFFRRASRREMYEAKSQKAEIKIQPSETERL 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scb	NP_523750.2	Int_alpha	51..103	CDD:214549	22/60 (37%)
		FG-GAP	350..388	CDD:460357	14/37 (38%)
		Int_alpha	409..459	CDD:214549	24/49 (49%)
		Int_alpha	473..>515	CDD:214549	15/41 (37%)
		Integrin_alpha2	509..829	CDD:462478	80/377 (21%)
itga3b	NP_001177238.1	Int_alpha	38..101	CDD:214549	26/69 (38%)
		Int_alpha	298..346	CDD:214549	18/48 (38%)
		Int_alpha	360..411	CDD:214549	24/50 (48%)
		Integrin_alpha2	457..906	CDD:462478	107/522 (20%)