DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8079 and GPATCH2L

DIOPT Version :9

Sequence 1:	NP_611023.1	Gene:	CG8079 / 36689	FlyBaseID:	FBgn0034002	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_016876916.1	Gene:	GPATCH2L / 55668	HGNCID:	20210	Length:	495	Species:	Homo sapiens

Alignment Length:	487	Identity:	82/487 - (16%)
Similarity:	141/487 - (28%)	Gaps:	192/487 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 IQDL-----ETCEQQQLLQYVEKLHGIIRKYDTKLASY--KQKLLHYVSREEKVSCDKASQATES 82
            :.||     :|.||.:|.:..|::....|:...:|...  :::...:....|...|  .|:|:||
Human    18 VHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCC--YSEASES 80

  Fly    83 ELQECQYSMENDEDTNKKDQPNDLSATDAFSFVDEMRQAAKHAENLNNFVYEHTSGMYYDPKTGY 147
            .|         ||.|  || ..:::....||..|:...|.:|.. ||..|
Human    81 SL---------DEAT--KD-CREVAPVTNFSDSDDTMVAKRHPA-LNAIV--------------- 117

  Fly   148 YYNAEYGLYYDGNNGCYYSYDHAKDSYEFHSQAQVQANDAAKPESEDEDLEVQFDELGGVITDHE 212
                                  ....:.:|.......|...:|                 :....
Human   118 ----------------------KSKQHSWHESDSFTENAPCRP-----------------LRRRR 143

  Fly   213 TLKKIKAE-----KQKAKDQAEKSKRKAKKKKSKKHS---------------------------K 245
            .:|::.:|     :||.|......:|..:.|.:||..                           .
Human   144 KVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLS 208

  Fly   246 KRSKKERRHKSKKRHRHSDDERSNDAEEGELSQSSDSSSDSSNEDSSSNTEDSS-------VPVF 303
            |..:|||........:...||..::.|...:..|||:...:::|....:.|.|.       ||.|
Human   209 KTGRKERMECETDEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGF 273

  Fly   304 ---------------------KAAGRFQDIAKKYP--PS-----------------------LRI 322
                                 ....:|.|.....|  |:                       .|:
Human   274 TVPNLLPKWAPDHCSEVERMDSGLDKFSDSTFLLPSRPAQRGYHTRLNRLPGAAARCLRKGRRRL 338

  Fly   323 IVQETNVESLKVGSL-HLIT-----YKGGSLGREGAHDVIIPDVNVSKCHLKFKYENKLGIYQCL 381
            :.:||::.:|....: |:|:     .|..:|..:..|        :|.|..:|   |.|.....|
Human   339 VGKETSINTLGTERISHIISDPRQKEKNKALASDFPH--------ISACAHEF---NPLSPLYSL 392

  Fly   382 DL--------------GSRNGTILNGSPMSSD 399
            |:              .:|...:..|.|.|.|
Human   393 DVLADASHRRCSPAHCSARQANVHWGPPCSRD 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8079	NP_611023.1	OCRE_VG5Q	124..177	CDD:293883	4/52 (8%)
		OCRE repeat 1	129..136	CDD:293883	2/6 (33%)
		OCRE repeat 2	137..144	CDD:293883	0/6 (0%)
		OCRE repeat 3	145..152	CDD:293883	0/6 (0%)
		OCRE repeat 4	153..159	CDD:293883	0/5 (0%)
		OCRE repeat 5	162..169	CDD:293883	0/6 (0%)
		FHA	346..411	CDD:278899	14/68 (21%)
		G-patch	516..560	CDD:279867
GPATCH2L	XP_016876916.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900