DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8079 and Y55D9A.2

DIOPT Version :9

Sequence 1:	NP_611023.1	Gene:	CG8079 / 36689	FlyBaseID:	FBgn0034002	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_502415.1	Gene:	Y55D9A.2 / 178216	WormBaseID:	WBGene00013224	Length:	511	Species:	Caenorhabditis elegans

Alignment Length:	522	Identity:	125/522 - (23%)
Similarity:	213/522 - (40%)	Gaps:	87/522 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 SFVDEMRQAAKHA------------ENLNNFVYEHTSGMYYDPKTGYYYNAE----YGLYYDGNN 161
            |..:.:|:||...            .|...: :.|..||:|:|.|..:|..|    |.|..:|:.
Worm     3 SMEEMLREAANEVLQSRIPPGYVLYPNYEQY-WSHEHGMFYNPDTEQFYRPEDKTVYQLNAEGSE 66

  Fly   162 GCYYSYDHAKDSYEFHSQAQVQAND---AAKPESEDEDLEVQFDELGGVITDHETLKKIKAEKQK 223
              |...:..|.:|......:.:|.|   :|:.:..|:: ||...|:...:.|    |.||.|:.:
Worm    67 --YVLVERRKPTYWASRSYRKRAIDLLGSAEFKKFDQN-EVNICEIAFGMVD----KVIKGEEME 124

  Fly   224 AKDQAEKSKRKAKKKKSKKHSKKRSKKERRHKSKKRHRHSDDERSNDAEEGELSQS-----SDSS 283
            .:.:..:|....|....:....|..|..||.|:..|...::.:.|:...|..|...     .|:.
Worm   125 KEKEYLRSIANNKVALMQHRINKVFKGNRRRKNPHRQYVANVDESSGHVEYTLQVDDYFDWEDAY 189

  Fly   284 SDSSNEDSSSNTEDSSVPVFKAAGRFQDIAKKYPPSLRIIVQETNVESLKVGSLHLITYKGGSLG 348
            .|:|:::.|.  :|....:....|..|      ||.:|:      :::|:  .||:||..||.||
Worm   190 EDNSDDEFSE--KDEQAVLMHQEGFDQ------PPCMRV------MDALR--RLHIITISGGYLG 238

  Fly   349 REGAHDVIIPDVNVSKCHLKFKYENKLGIYQCLDLGSRNGTILNGSPM-SSDAMDLVHGSVITLG 412
            .:...::::.:..:.:...:..|..:...|....|.......:||:.: :|..:||..|..|.|.
Worm   239 SDRDCEIVVSNQLLPERCAEIVYSEEAQCYSIEKLEDACILQVNGNNVKTSSPVDLCQGDSILLS 303

  Fly   413 QTRLLCHVHEGNSTCGLCEPGLL--IENSPPVVAAVASSTASVLSHKEQLKKLQRKYGLE----- 470
            ..|...|||.|::||..|||||.  .::..||....|.:....::.::.||::.:.||:.
Worm   304 GERFDVHVHNGSNTCPGCEPGLQQGDDDIAPVTTVPAKNIRGEVARRKNLKQMMKSYGIRPDDVL 368

  Fly   471 NEKFVDTSGNGQSNYNDRAATRRVQVGSSTD-------KEKTE---------------VACVNTE 513
            :|........|.|..|   ..|....|||:|       |...|               .|.....
Worm   369 SEPIRKRPATGPSEMN---IHRSEAPGSSSDMYGSCAAKPMPEGQRKFDLPSTSAAVAAAAAPKP 430

  Fly   514 IGSSNKGFKMLSKLGWQKGEKLGKTNASAGLLEPINVVANEGTSGLGNSD---PVLS-SSRTIDK 574
            :.|.|.|||:|..:||.:|:.|||  ...|.:||:.........|||.::   |..| ..:.::|
Worm   431 LDSGNVGFKLLKSMGWSEGQGLGK--EKQGHVEPVATEVKNNRKGLGANEKEPPTKSYKDQVLEK 493

  Fly   575 RK 576
            .|
Worm   494 TK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8079	NP_611023.1	OCRE_VG5Q	124..177	CDD:293883	15/68 (22%)
		OCRE repeat 1	129..136	CDD:293883	0/6 (0%)
		OCRE repeat 2	137..144	CDD:293883	3/6 (50%)
		OCRE repeat 3	145..152	CDD:293883	2/6 (33%)
		OCRE repeat 4	153..159	CDD:293883	2/5 (40%)
		OCRE repeat 5	162..169	CDD:293883	1/6 (17%)
		FHA	346..411	CDD:278899	12/65 (18%)
		G-patch	516..560	CDD:279867	16/43 (37%)
Y55D9A.2	NP_502415.1	OCRE	17..70	CDD:293880	13/55 (24%)
		OCRE repeat 1	22..29	CDD:293880	0/6 (0%)
		OCRE repeat 2	30..37	CDD:293880	0/7 (0%)
		OCRE repeat 3	38..45	CDD:293880	3/6 (50%)
		OCRE repeat 4	46..52	CDD:293880	2/5 (40%)
		OCRE repeat 5	54..61	CDD:293880	1/6 (17%)
		G_patch	431..477	CDD:197727	18/47 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	103	1.000	Inparanoid score	I3536
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D334272at33208
OrthoFinder	1	1.000	-	-		FOG0006982
OrthoInspector	1	1.000	-	-		oto19479
orthoMCL	1	0.900	-	-		OOG6_106578
Panther	1	1.100	-	-	LDO	PTHR23106
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4438
SonicParanoid	1	1.000	-	-		X5069
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.930