DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and lipa

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	406	Identity:	152/406 - (37%)
Similarity:	229/406 - (56%)	Gaps:	26/406 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LVVQLIAVFLSLGLANALP--------------ADTGRASSVTTVTIVRGHGYEIEEHEVQTSDG 52
            |:|.:.|:..::.|.:.:|              ||.....:::  .::|..||..||:||.|.||
Frog     8 LLVAVTALIPAVALTDDVPSRIRHGVAGDLLYSADPEATMNIS--ELIRYRGYPSEEYEVLTEDG 70

  Fly    53 YILTMHRIPYSKNTGYDGPRPVVFLMHGLLCSSSDWVLAGPHSGLAYLLSEAGYDVWMGNARGNT 117
            |||:::|||:......:||:|||||.||||...|:||....::.|.::|::||||||:||:||||
Frog    71 YILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNT 135

  Fly   118 YSKRHASKSPLLQPFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLTYVGHSQGTTSFFVLNSMIPR 182
            :|::|.|.||..:.||.|.:.::...||||::|::...|...|:.|||||||||..|:..|.:|:
Frog   136 WSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQ 200

  Fly   183 FKSRIRSAHLLAPVAWMEHMESPLATVGGPLLGQPNAFV-ELFGSAEFLPNTQLMNLFGALLCSD 246
            ...:|:....|||||.::..:||||.:|  :|  |...: ||||..||||.|.|:.......|:
Frog   201 LAKKIKMYFGLAPVATVKFSKSPLAKLG--VL--PEFLIEELFGKGEFLPQTYLITWLATHFCT- 260

  Fly   247 EAISQFMCTNTLFLLGGWNSPYINETLLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGSTR 311
            .||:..:|.|..|||.|:|...:|.:.:....:..|||.||..:.|:.|...||..:.||:|:..
Frog   261 HAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKG 325

  Fly   312 NKKEYSSKTPPEYDVEGIDVPTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHID 376
            |...|:..|||.|.|..:.|||.|:...||:.|...||..|...::    ...|......|.|:|
Frog   326 NMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQVS----NLVYHKEIPDWEHLD 386

  Fly   377 FLWGLNIKEILYDRVI 392
            |:|||:..|.:|:.:|
Frog   387 FIWGLDAPERMYNEII 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	148/397 (37%)
		Abhydro_lipase	31..92	CDD:282003	30/60 (50%)
		Abhydrolase_5	74..>214	CDD:289465	63/139 (45%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	30/62 (48%)
		PLN02872	50..409	CDD:215470	145/364 (40%)
		Abhydrolase_5	91..>229	CDD:289465	64/139 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I2528
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2899
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm47739
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080