DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and CG6753

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_650219.2	Gene:	CG6753 / 41557	FlyBaseID:	FBgn0038070	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	396	Identity:	161/396 - (40%)
Similarity:	236/396 - (59%)	Gaps:	5/396 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVQLIAVFLSLGLANALPADTGRASSVT-TVTIVRGHGYEIEEHEVQTSDGYILTMHRIP-YSKN 65
            ||.|....|.|...:.......|...:| .|..::..||.:|.|.|.|.|||:||:|||| ....
  Fly     6 VVLLCLALLGLQQVSRATLRQSREIIITDAVRRIQNDGYNVERHSVTTKDGYVLTLHRIPQVDPE 70

  Fly    66 TGYDGPRPVVFLMHGLLCSSSDWVLAGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHASKSPLLQ 130
            .|....||||||:.||..||..|:|.|....|||||..||||||:||.|||.|.:::..::...:
  Fly    71 LGSLLRRPVVFLLSGLYASSDVWLLNGREDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTER 135

  Fly   131 PFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRSAHLLAP 195
            .||:|.||::|:|||||.:||||..|....:.:||.|||.|.|.|||||:|::.:..:||.||||
  Fly   136 EFWDFSWHEMGVYDLPAQVDYVLRTTGQKAMHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAP 200

  Fly   196 VAWMEHMESPLATVGGPLLGQPNAFVELFGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLFL 260
            ||::.:.:|.||.|.||:||..|...::....|.....:....|.::.|.:.. ...:|.:.|:.
  Fly   201 VAYVSNTKSGLAKVIGPVLGTRNYVSKMLEGVEMFSTNKFFKKFLSMTCLENE-KPLVCISRLWP 264

  Fly   261 LGGWNSPYINETLLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGSTRNKKEYSSKTPPEYD 325
            ..|:::.::|:|||||:||..|||.||.|:.||.|.|.|..|||:|||..||...|....||||.
  Fly   265 AVGYDTRFLNKTLLPDLMANFPAGGSVKQLMHYFQGYVSTRFRQYDYGPERNWLHYQQLEPPEYA 329

  Fly   326 VEGIDVPTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILYDR 390
            :|.:..|..:::|:|||..:..|:.|| .|..|: :::.|::|.::|||.||:.||.::|.::|.
  Fly   330 LENVSTPVTVFFSENDYIVAPADIWRL-LTRLPN-VEAVYKVPWKRWNHFDFICGLGVREYIFDN 392

  Fly   391 VINDIN 396
            ::..:|
  Fly   393 IVLSMN 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	157/384 (41%)
		Abhydro_lipase	31..92	CDD:282003	29/61 (48%)
		Abhydrolase_5	74..>214	CDD:289465	71/139 (51%)
CG6753	NP_650219.2	PLN02872	39..394	CDD:215470	152/357 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471661
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900