DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and lipf

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_998569.1	Gene:	lipf / 406713	ZFINID:	ZDB-GENE-040426-2737	Length:	396	Species:	Danio rerio

Alignment Length:	399	Identity:	146/399 - (36%)
Similarity:	219/399 - (54%)	Gaps:	17/399 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLVVQLIAVFLSLGLA----NALPADTGRASSV--TTVTIVRGHGYEIEEHEVQTSDGYILTMHR 59
            ||.:.|..|.|:.||.    :||.. ||....|  ....|:|..||..||.||.|.|||||:::|
Zfish     1 MLWLVLSLVILTSGLVQYGQSALDG-TGLDPEVNMNISEIIRHWGYPAEEFEVVTEDGYILSINR 64

  Fly    60 IPYSKNTGYDGPRPVVFLMHGLLCSSSDWVLAGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHAS 124
            ||:......:..:|||||.||||.:.|:||...|::.|.::|::||:|||:||:||||:|.:|.|
Zfish    65 IPHGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVS 129

  Fly   125 KSPLLQPFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRS 189
            ..|..:.:|.|...::...||||:::::...|...|:.|||||||||..|:..|.:|...|:|:.
Zfish   130 LDPRQKEYWKFSHDEMAKKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELASKIKM 194

  Fly   190 AHLLAPVAWMEHMESPLATVGGPLLGQPNAFV-ELFGSAEFLPNTQLMNLFGALLCSDEAISQFM 253
            ...|||||.:...:||:.    .|...|...: :|||..:|.|..:|:..|....||.:.:| .:
Zfish   195 FFALAPVATVGMTKSPMT----KLSVIPEFLIWDLFGQKDFFPQNELIKFFATEFCSRKPLS-VL 254

  Fly   254 CTNTLFLLGGWNSPYINETLLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGSTRNKKEYSS 318
            |.|..|||.|::...:|.:..|...|..|||.||..:.|:.|...|.....:|||...|...|:.
Zfish   255 CGNVFFLLCGFDEKNLNMSRTPVYTAHCPAGTSVQNMIHWAQAVKSSKLMAYDYGRAGNMAHYNQ 319

  Fly   319 KTPPEYDVEGIDVPTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNI 383
            .|||.|:::.:.|||.::....|..|...|| .|..|..|   |..|:...:.|.|:||:||::.
Zfish   320 STPPLYNIQDMMVPTAVWSGGQDTLADPKDV-ALLLTQIP---KLVYKRDIKHWEHLDFIWGMDA 380

  Fly   384 KEILYDRVI 392
            .:.:|:::|
Zfish   381 PQEMYEKMI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	142/389 (37%)
		Abhydro_lipase	31..92	CDD:282003	29/60 (48%)
		Abhydrolase_5	74..>214	CDD:289465	58/139 (42%)
lipf	NP_998569.1	PLN02872	4..393	CDD:215470	144/396 (36%)
		Abhydro_lipase	36..97	CDD:282003	29/60 (48%)
		Abhydrolase_5	78..242	CDD:289465	67/167 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574728
Domainoid	1	1.000	205	1.000	Domainoid score	I2877
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3034
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810